PURPOSE: In the ENGOT-OV16/NOVA trial (ClinicalTrials.gov identifier: NCT01847274), maintenance therapy with niraparib, a poly(ADP-ribose) polymerase inhibitor, prolonged progression-free survival in patients with platinum-sensitive, recurrent ovarian cancer who had a response to their last platinum-based chemotherapy. The objective of the study was to assess the clinical benefit and patient-repor

Literature on familial risk of carcinomas in situ (CISs) is limited because many cancer registries do not collect information on CIS. In Sweden CISs are collected, and we used these data to analyze familial relative risks (RRs) for concordant (CIS-CIS) types of anogenital (cervical, other female and male genital and anal) and skin squamous cell CIS; additionally RRs were assessed between CIS types

Vasopressin-dependent trafficking of AQP2 in the renal collecting duct is crucial for the regulation of water homeostasis. This process involves the targeting of AQP2 to the apical membrane during dehydration as well as its removal when hydration levels have been restored. The latter involves AQP2 endocytosis and sorting into multivesicular bodies (MVB), from where it may be recycled, degraded in

In this paper, we suggest that psychology as a science, and especially as a clinical practice, can develop new ways of thinking and working with clients by including critical, feminist, and norm-critical approaches. Ethical guidelines highlight that psychologists should respect the client’s rights and dignity. New policies for evidence-based psychological practice also emphasize responsiveness to

The mobilisation of psychologists in Sweden working for lesbian, gay, bisexual, trans* and queer (LGBTQ) wellbeing and rights has so far not succeeded in creating continuity despite several attempts to establish some kind of organisation since the mid 1990s. A new attempt was made in 2013 when the Swedish LGBTQ network for psychologists was formed following a formal decision at the congress of the

Plasma accelerators present one of the most suitable candidates for the development of more compact particle acceleration technologies, yet they still lag behind radiofrequency (RF)-based devices when it comes to beam quality, control, stability and power efficiency. The Horizon 2020-funded project EuPRAXIA ("European Plasma Research Accelerator with eXcellence In Applications") aims to overcome t

In a seminal article, Fano predicts that absorption of light occurs preferably with increase of angular momentum. We generalize Fano's propensity rule to laser-assisted photoionization, consisting of absorption of an extreme-ultraviolet photon followed by absorption or emission of an infrared photon. The predicted asymmetry between absorption and emission leads to incomplete quantum interference i

Three-dimensional (3D) x-ray microscopy by ptychographic tomography requires elaborate numerical reconstructions. We describe a coupled ptychography-tomography reconstruction algorithm and apply it to an experimental ptychographic x-ray computed tomography data set of a catalyst particle. Compared to the traditional sequential algorithm, in which ptychographic projections are reconstructed to serv

Book Review: Gulag Memories. The re-discovery and com-memoration of Russia’s repressive past, Zuzanna Bogumil New York & Oxford: Berghahn Books 2018.

The use of clinical autopsy has been in decline for many years throughout healthcare systems of developed countries despite studies showing substantial discrepancies between autopsy results and pre-mortal clinical diagnoses. We conducted a study to evaluate over time the use and results of clinical autopsies in Sweden. We reviewed the autopsy reports and autopsy referrals of 2410 adult (age > 17)

OBJECTIVE: To examine how intersections of multiple sociodemographic variables explain the individual heterogeneity in risk of being diagnosed with any of following chronic rheumatic diseases (CRDs): osteoarthritis (OA), gout, rheumatoid arthritis (RA), or spondyloarthritis (SpA).METHODS: We identified people aged 40-65 years residing in Skåne, Sweden, by 31st December 2013 and having done so from