Context: A strong association between autoimmune Addison's disease (AAD) and major histocompatibility complex class II-encoded HLA-DRB1-DQA1-DQB1 haplotypes is well known. Recent evidence from other autoimmune diseases has suggested that class I-encoded HLA-A and HLA-B gene variants confer HLA-DRB1-DQA1-DQB1-independent effects on disease. Objective: We aimed to explore AAD predisposing effects of

Clothes, culture, identity

Loss of cognitive function and hypertension are two common conditions in the elderly and both significantly contribute to loss of personal independency. Microvascular brain damage - the result of age-associated alteration in large arteries and the progressive mismatch of their cross-talk with small cerebral arteries - represents a potent risk factor for cognitive decline and for the onset of demen

Homogeneous gels represent a new type of (electro)chromatographic media possessing unique separation properties unmatched with any other chromatographic beds. It is important to emphasize that they principally differ from continuous beds, polymer rods (better known as monoliths), which are particulate separation media with pores permitting hydrodynamic flow through the columns. Monoliths, thus, ar

Landfilling is the most commonly used method for solid waste disposal in Jordan. It is an important source of pollution, which can be displayed through analysis of data for climatic conditions, hydrology and geology of the country. The migration of gas and leachate from the landfill body into the surrounding environment present a serious environmental concern, which include groundwater pollution,

This paper argues that Person interprets event participants in relation to speech participants in a parallel fashion as grammatical Tense interprets event time in relation to speech time. This understanding of Person is embedded in a general theory of speech-grammar-event matching, that is to say, an approach where speech (event) features, SF, are matched by grammatical features, GF, which in turn

OBJECTIVE: /st> To investigate the effect of tumour necrosis factor (TNF) antagonist treatment of patients with rheumatoid arthritis (RA) on sick leave (SL) and disability pension (DP) in a population-based setting in southern Sweden. METHODS: /st> All patients with RA in the South Swedish Arthritis Treatment Group register living in the county of Skåne (population 1.2 million), who started their

Brain-derived neurotrophic factor (BDNF) plays an important role in neuronal survival through activation of TrkB receptors. The trkB gene encodes a full-length receptor tyrosine kinase (TrkB.FL) and its truncated (T1/T2) isoforms. We investigated the changes in TrkB protein levels and signaling activity under excitotoxic conditions, which are characteristic of brain ischemia, traumatic brain injur

Anticipatory and predictive models are becoming very important features of robot systems. This thesis investigates some aspects of predictive modeling. Is prediction always a good thing? How important is it to anticipate what will happen in the future? Is it better to anticipate far into the future or to focus on the next few seconds? What are the requirements for predictive models? Predictive mod