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Resonant interaction between localized and extended vibrational modes in Si: O-18 under pressure

The interaction between localized and extended vibrational modes in solids is of central importance in understanding how local vibrational modes decay into phonons. Interstitial oxygen (O-i) in silicon is a model system for studying such interactions. Using hydrostatic pressure, we have brought the antisymmetric stretch mode of O-18(i) in silicon into resonance with the second harmonic of the O-18

Dissection of a locus on mouse chromosome 5 reveals arthritis promoting and inhibitory genes

Introduction In a cross between two mouse strains, the susceptible B10.RIII (H-2r) and resistant RIIIS/J (H-2r) strains, a locus on mouse chromosome 5 (Eae39) was previously shown to control experimental autoimmune encephalomyelitis (EAE). Recently, quantitative trait loci (QTL), linked to disease in different experimental arthritis models, were mapped to this region. The aim of the present study

Balance and gait performance in an urban and a rural population

OBJECTIVE: To compare the differences in standing balance and gait performance between two populations, correlated with age and physical activities of daily living. DESIGN: A cross-sectional study. SETTINGS: Malmo, the third largest city in Sweden, and Sjobo, a typical agricultural community 60 km east of Malmo. PARTICIPANTS: Participants were 570 men and women from the urban community (urban) and

Unilateral versus bilateral neck exploration for primary hyperparathyroidism - Five-year follow-up of a randomized controlled trial

Objective: To compare long-term patient outcome in a prospective randomized controlled trial between unilateral and bilateral neck exploration for primary hyperparathyroidism (pHPT). Summary Background Data: Minimal invasive and/or focused parathyroidectomy has challenged the traditional bilateral neck exploration for pHPT. Between 1997 and 2001, we conducted the first unselected randomized contro

Childhood cancer survival trends in Europe: a EUROCARE Working Group study

PURPOSE: EUROCARE collected data from population-based cancer registries in 20 European countries. We used this data to compare childhood cancer survival time trends in Europe. PATIENTS AND METHODS: Survival in 44,129 children diagnosed under the age of 15 years during 1983 to 1994 was analyzed. Sex- and age-adjusted 5-year survival trends for 10 common cancers and for all cancers combined were es

Objectifying the past - Lakota responses to western historiography

This article discusses an emergent indigenous counter-discourse. on Lakota (Sioux) Indian history. This discourse challenges the widely accepted narrative of Lakota history that sets their date of arrival in the-Black Hills of South Dakota in the 18th century. Modern Lakota historians maintain that the Lakotas have always been in the sacred Black Hills and that the conventional narrative of the La

Limitations of chromosome classification by multicolor karyotyping

Multicolor karyotyping technologies, such as spectral karyotyping (SKY) (Schrock et al.1996; Liyanage et al. 1996) and multiplex (M-) FISH (Speicher et al. 1996), have proved to be extremely useful in prenatal, postnatal, and cancer cytogenetics. However, these technologies have inherent limitations that, in certain situations, may result in chromosomal misclassification. In this report, we presen

Activation of the Human Contact System on Neutrophil Extracellular Traps

Pattern recognition is an integral part of the innate immune system. The human contact system has been shown to interact with the surface of many bacterial and fungal pathogens, and once activated leads to the generation of antimicrobial peptides and the proinflammatory mediator bradykinin. Here we show that apart from these surfaces also neutrophil extracellular traps (NETs) provide a surface tha

Paleomagnetism and Ar-40/Ar-39 geochronology of Yemeni Oligocene volcanics: Implications for timing and duration of Afro-Arabian traps and geometry of the Oligocene paleomagnetic field

A combined paleomagnetic and Ar-40/Ar-39 study was carried out along eight stratigraphically overlapping sections in the Oligocene Afro-Arabian flood volcanic province in Yemen (73 sites). The composite section covers the entire volcanic stratigraphy in the sampling region and represents five polarity zones that are correlated to the geomagnetic polarity time scale based on Ar-40/Ar-39 ages from t

Improved chip design for integrated solid-phase microextraction in on-line proteomic sample preparation

A recently introduced silicon microextraction chip (SMEC), used for on-line proteomic sample preparation, has proved to facilitate the process of protein identification by sample clean up and enrichment of peptides. It is demonstrated that a novel grid-SMEC design improves the operating characteristics for solid-phase microextraction, by reducing dispersion effects and thereby improving the sample

Bilateral deep brain stimulation in Parkinson's disease: a multicentre study with 4 years follow-up

Deep brain stimulation (DBS) is associated with significant improvement of motor complications in patients with severe Parkinson's disease after some 6-12 months of treatment. Long-term results in a large number of patients have been reported only from a single study centre. We report 69 Parkinson's disease patients treated with bilateral DBS of the subthalamic nucleus (STN, n = 49) or globus pall

Osteolytic potential of triphenyl bismuth as an alternative contrast medium in acrylic bone cement

Radiopaque cement containing barium sulfate causes significantly more bone resorption in vivo and in vitro than radiolucent cement. The aim of this study was to investigate the osteolytic potential of an alternative radiopaque agent, triphenyl bismuth (TPB). Bone cement particles containing various concentration of TPB (15 and 25 wt%) prepared by two methods, blending and dissolution, were added t

Antisense RNAs everywhere?

In recent years, systematic searches of both prokaryote and eukaryote genomes have identified a staggering number of small RNAs, the biological functions of which remain unknown. Small RNA-based regulators are well known from bacterial plasmids. They act on target RNAs by sequence complementarity; that is, they are antisense RNAs. Recent findings suggest that many of the novel orphan RNAs encoded

Global existence for parabolic systems by Lyapunov functions

We present a result on the global existence of classical solutions for quasilinear parabolic systems with homogeneous Dirichlet boundary conditions in bounded domains with a smooth boundary. Our method relies on the use of Lyapunov functions.

T-RFLP combined with principal component analysis and 16S rRNA gene sequencing: an effective strategy for comparison of fecal microbiota in infants of different ages

The fecal microbiota of two healthy Swedish infants was monitored over time by terminal restriction fragment length polymorphism (T-RFLP) analysis of amplified 16S rRNA genes. Principal component analysis (PCA) of the T-RFLP profiles revealed that the fecal flora in both infants was quite stable during breast-feeding and a major change occurred after weaning. The two infants had different sets of

Prognosis and clinical presentation of BRCA2-associated breast cancer

54 female breast cancer patients from 22 families with BRCA2 germ line mutations from Sweden and Denmark were compared with 214 age- and date of diagnosis-matched controls identified among breast cancer patients from South Sweden. At diagnosis, BRCA2-associated cases were more often node-positive (N+). OR=1.9 (95% confidence interval (CI)=1.0-3.6; P=0.036), and were more often clinical stage IV: O

Formal asymptotic models of vehicular traffic. Model closures

Formal closed models for vehicular traffic flow are obtained based on the novel equilibrium solution of the Prigogine--Herman equation. To that effect, Hilbert and Chapman--Enskog asymptotic series expansions are employed, obtaining the Euler and Navier--Stokes equivalent equations for traffic flow.