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The epidemiology of total hip replacement in the Netherlands and Sweden - Present status and future needs

By combining data from the Discharge registers and the census bureaus in The Netherlands and Sweden, we calculated the age-specific incidences of primary total hip replacement (THR), studied the demographic profile of the population receiving THR and predicted demands. In the period 1986-1997, the number of THRs increased by 20% in Sweden to 10,000 operations (1131100,000 inhabitants) and by 68% t

CD-sens and clinical changes during withdrawal of Xolair after 6 years of treatment

Background: Many clinical trials with omalizumab, Xolair, have been reported but the treatment period has always been short, i.e. < 12 months. After withdrawal, the clinical symptoms tend to return. A group of patients who stopped treatment after approx. 6 years allowed studies of the long-term effects of Xolair. Methods: The patient's cat or mite allergen sensitivity was quantitated as basophil a

Paradoxical decrease in cytosolic calcium with increasing depolarization by potassium in guinea-pig mesotubarium smooth muscle

The free intracellular Ca2+ concentration ([Ca2+]i) was measured simultaneously with isometric force in strips of guinea-pig mesotubarium using the Fura-2 technique. [Ca2+]i and force were maximal at a relatively low (30 mM) concentration of extracellular K+ ([K+]o), and declined at 90 and 140 mM K+. Plateau values of both [Ca2+]i and force were higher in the presence of 5.10(-6) M ryanodine, indi

Risk of myocardial infarction in relation to plasma levels of homocysteine and inflammation-sensitive proteins: a long-term nested case-control study.

Several studies have found that the homocysteine plasma level is associated with cardiovascular disease. The authors previously described a relationship between concentrations of fibrinogen and other inflammation-sensitive plasma proteins, namely, alpha1-antitrypsin, ceruloplasmin, haptoglobin, and orosomucoid (alpha1-acid glucoprotein) and the incidence of myocardial infarction (MI). Whether leve

Binding of extracellular matrix molecules by probiotic bacteria.

Aims: The aim of this study was to investigate extracellular matrix (ECM) and mucin binding of selected bacterial isolates with probiotic features in comparison with commercially used probiotic bacteria. Methods and Results: ECM molecules were immobilized in microtitre plates ( mucin and fetuin) or on the surface of latex beads. Porcine mucin was bound by all 13 probiotic strains tested with impo

Lärares raster : innehåll i mellanrum

Popular Abstract in Swedish Studien har som syfte att beskriva lärares raster och att utifrån fältets problem generera en konkret teori om rasternas innehåll och betydelse för lärares arbete. I de inledande observationerna av lärares raster, som görs av 144 lärarstudenter på sin första praktik, beskrivs att lärare ägnar stor del av rasterna åt att fortsätta undervisa. De fortsätter att förklara ocThis study, in which a Grounded Theory approach is used, attempts to determine what happens during teachers’ recess periods and the effect these interspaces might have on the everyday work of teachers. The aim is to generate a concrete theory out of observations and interviews, simultaneously showing what’s going on in the field and taking into account the main concerns of those acting there.The f

DC bus voltage control for a distributed power system

This paper addresses voltage control of distributed dc power systems. DC power systems have been discussed as a result of the introduction of renewable, small-scale power generation units. Also, telecommunication power systems featuring UPS properties might benefit from a broader introduction of dc power systems. Droop control is utilized to distribute the load between the source converters. In or

High prevalence of osteoarthritis 14 years after an anterior cruciate ligament tear in male soccer players: a study of radiographic and patient relevant outcomes.

Objective: To identify the consequences of an anterior cruciate ligament (ACL) tear in a cohort of male soccer players 14 years after the initial injury with respect to radiographic knee osteoarthritis and patient relevant outcomes. Methods: Of 219 male soccer players with an ACL injury in 1986, 205 (94%) were available for follow up after 14 years; 75% of the cohort (154/205) answered mailed que

Fall och höftfraktur hos äldre går att förebygga

Efter snart 30 år av forskning måste även vi i Sverige tillämpa den evidens som finns för att förhindra fallolyckor, frakturer och onödigt lidande. Stora samhällsekonomiska besparingar är möjliga.

Dynamic speed adaptation based on information technology - a theoretical background

Knowledge on the factors influencing driver speed-behaviour, the relationship between speed and traffic safety and means to influence speed behaviour is systematised. Expert judgements and the high proportion of injury accidents show that improved speed adaptation has the largest safety potential in the following situations: - Road surface-, visibility and weather affected situations (e.g. slipper

European Prospective Investigation into Cancer and Nutrition (EPIC) calibration study: rationale, design and population characteristics

The European Prospective Investigation into Cancer and Nutrition (EPIC), which covers a large cohort of half a million men and women from 23 European centres in 10 Western European countries, was designed to study the relationship between diet and the risk of chronic diseases, particularly cancer. Information on usual individual dietary intake was assessed using different validated dietary assessm