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Sepsis Is Underreported in Swedish Intensive Care Units: A Retrospective Observational Multicentre Study

BackgroundSepsis is a common indication for admission to the intensive care unit (ICU). Since definitions vary across studies, comparisons of prevalence and outcomes have been challenging. We aimed to compare sepsis according to ICU discharge codes with sepsis according to Sepsis‐3 criteria and to investigate the epidemiology of sepsis in the ICU. We hypothesized that sepsis using discharge codes

Perception of societal influence among civil society leaders – an elite perspective

This article explores the perception of societal influence of civil society leaders based on a survey study conducted in 2017 among leaders of Swedish civil society organizations. Civil society leaders represent organizations that are often based on and guided by religious, political, or cultural values and that often strive to achieve some sort of social change. To exercise influence on society i

Lignin Depolymerisation under Continuous-Flow Conditions : Highlights of Recent Developments

Lignin is a poly-aromatic polymer contained in the plant cell wall, and it is considered the most abundant non-carbohydrate polymer on Earth. The aromaticity and richness of its functional groups render lignin an attractive starting biomacromolecule for conversion into a variety of value-added products. The development of successful strategies for lignin valorisation infers the design of effective

Relationship between cortical iron and tau aggregation in Alzheimer's disease

A growing body of evidence suggests that the dysregulation of neuronal iron may play a critical role in Alzheimer's disease. Recent MRI studies have established a relationship between iron accumulation and amyloid-β aggregation. The present study provides further insight demonstrating a relationship between iron and tau accumulation using magnetic resonance-based quantitative susceptibility mappin

Effects of storage conditions on degradation of chlorophyll and emulsifying capacity of thylakoid powders produced by different drying methods

Thylakoid membranes isolated from spinach have previously been shown to inhibit lipase/co-lipase and prolong satiety in vivo. There is a need to develop thylakoid products that not only have the desired characteristics and functionality after processing, but also are stable and provide equivalent effect on appetite over the promised shelf life. The aim of the present study was therefore to evaluat

Assessing Radiographic Response to 223Ra with an Automated Bone Scan Index in Metastatic Castration-Resistant Prostate Cancer Patients

For effective clinical management of patients being treated with 223Ra, there is a need for radiographic response biomarkers to minimize disease progression and to stratify patients for subsequent treatment options. The objective of this study was to evaluate an automated bone scan index (aBSI) as a quantitative assessment of bone scans for radiographic response in patients with metastatic castrat

Emulsifying and anti-oxidative properties of proteins extracted from industrially cold-pressed rapeseed press-cake

One of the functional proteins in rapeseed-the amphiphilic protein oleosin-could be used to stabilize emulsions. The objectives of this study were to extract oleosins from cold-pressed rapeseed press-cake, optimize the extraction process, and investigate their emulsifying and anti-oxidative capacity. The proteins were recovered from industrially cold-pressed rapeseed press-cake at different alkali

The length and number of sedentary bouts predict fibrinogen levels in postmenopausal women

Menopause is associated with adverse changes in coagulation homeostasis. We aimed to investigate the association between objectively measured sedentary behavior (SB) and SB bouts (i.e., number and length of SB bouts) vs. fibrinogen levels in post-menopausal women. Fifty-three post-menopausal women (age 59.8 ± 6.2 years, BMI 27.3 ± 4.4) wore a multisensory device (Sensewear Mini Armband, BodyMedia,

Improving the description of multiple interactions in Herwig

The modeling of multiple parton interactions in Monte Carlo event generators is a crucial part not only for the dressing of signal processes but also to describe data with a minimum bias on the event selection. Much work has and will be put into the theoretical framework and the numerical implementation of these models. In this contribution, we document various improvements of the multiple parton

Warmer climate projections in EC-Earth3-Veg : The role of changes in the greenhouse gas concentrations from CMIP5 to CMIP6

Climate projections for the 21st century for CMIP6 are warmer than those for CMIP5 despite nominally identical instantaneous radiative forcing. Many climate modeling groups attribute the stronger warming in the CMIP6 projections to the higher climate sensitivity of the new generation of climate models, but here we demonstrate that also changes in the forcing datasets can play an important role, in

The Shape of the Correlation Function

The correlation function measured in ultrarelativistic nuclear collisions is non-Gaussian. By making use of models we discuss and assess how much various effects can influence its shape. In particular, we focus on the parametrisations expressed with the help of Lévy-stable distributions. We show that the Lévy index may deviate substantially from 2 due to non-critical effects such as non-spherical

Frequency-selective wallpaper for indoor interference reduction and MIMO capacity improvement

This paper presents the design and features of frequency-selective wallpaper-based on periodic and symmetric metallic hexagons-intended to be attached to standard walls for filtering out 5GHz signals (e.g., IEEE 802.11a systems)without blocking other selected radio communication services (e.g., cellular mobile communication signals). It analyzes the characteristics of the radio channel-as found wi

Dual-precision fixed-point arithmetic for low-power ray-triangle intersections

Ray-Triangle intersection is a fundamental computation in most ray tracing algorithms. The prohibitive cost of the ray-triangle test algorithms, however, limits the utilization of these algorithms in settings with low power budgets, such as mobile systems. In this work, we analyze the precision requirements for ray-triangle intersection and observe that for most of the rays a low-precision is suff

Closely related dinoflagellate species in vastly different habitats–an example of a marine–freshwater transition

Phytoplankton are present in a large variety of aquatic environments, ranging from small freshwater ponds to the oceans. Typically, freshwater and marine species are not closely related, indicating an ancient divergence and that salinity poses a strong dispersal barrier. Here we reveal a common recent origin of two dinoflagellates that are well adapted to different habitats. Gymnodinium baicalense

Pre-treatment allostatic load and metabolic dysregulation predict SSRI response in major depressive disorder : A preliminary report

BackgroundMajor depressive disorder (MDD) is associated with increased allostatic load (AL; a measure of physiological costs of repeated/chronic stress-responding) and metabolic dysregulation (MetD; a measure of metabolic health and precursor to many medical illnesses). Though AL and MetD are associated with poor somatic health outcomes, little is known regarding their relationship with antidepres

The changes in ENSO-induced tropical Pacific precipitation variability in the past warm and cold climates from the EC-Earth simulations

The El Niño-Southern Oscillation (ENSO) is one of the most significant climate variability signals. Studying the changes in ENSO-induced precipitation variability (ENSO precipitation) in the past climate offers a possibility to a better understanding of how they may change under future climate conditions. This study uses simulations performed with the European community Earth-System Model (EC-Eart

Conceptual Design of a Kraft Lignin Biorefinery for the Production of Valuable Chemicals via Oxidative Depolymerization

Lignin is the most abundant aromatic biopolymer on Earth, and its aromatic structure makes it a promising platform for the production of biobased chemicals and other valuable building blocks. The valorization of lignin into chemicals currently presents a challenge, and its facilitation is key in the development of viable lignocellulosic biorefinery processes. This study presents a conceptual desig