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Exploring the effects of platinum compounds on RNA, adduct formation, thermal melting properties and siRNA down regulation capacity of gene targets associated

Since its discovery, RNA interference (RNAi) has turned into an invaluable research tool for regulating gene expression. Furthermore, this naturally occurring phenomenon in mammalian cells is of interest in cancer research, both as a possible therapeutic approach and a target for cancer treatment. Platinum anticancer agents like cisplatin are considered one of the most active cancer drugs used eit

Hållbara scenarier och affärsmodeller för specialistkliniker i Sverige folksjukdomen artros i Stockholms läns landsting som exempel -

Ten per cent of the population in the western world suffer from osteoarthritis – a widespread endemic disease that is estimated to cost the Swedish society equivalent to two per cent of the Swedish GNP annually, corresponding to over 50 billion SEK in 2009 in treatments and lost productivity. With an increasing aging population the incidence of osteoarthritis is expected to be further enhanced. In

Optimizing retailer inventory levels

Background & Problem: In previous years, there has been low focus on inventory control. Due to high margins on the products, a high inventory level has been kept to reduce the risk for lost sales. Today, the company is expanding, and therefore need to improve the inventory control to reduce tied-up capital. Purpose: The main purpose of this thesis is to reduce capital tied-up in inventories. B

Cavity Ring-Down Spectroscopy in Analytical Techniques

Cavity ring-down spectroscopy (CRDS) is a sensitive absorption spectroscopy technique, used in the detection of very weak transitions and trace species. A laser pulse is trapped in an optical cavity, in which the intensity decays exponentially. The decay is faster in the presence of an absorbing or scattering material. In this work the method is applied in two analytical techniques. In the first,

Quantum Dots Sensitized ZnO Nanowires Solar Cells

In this project, solar cell based on CdSe quantum dots sensitized onto ZnO nanowires was well fabricated. The following quantum dot-nanowire linker molecules were used: 3- mercaptoproponic acid (3-MPA) and 2-mercaptoproponic acid (2-MPA). The best solar cell efficiency was observed with 3-MPA linker molecule. Solar cell efficiency for different lengths of ZnO NWs and different sensitization times

Method development and applications - hollow fiber SLM extraction of mono and dicarboxylic acids

A highly sensitive (LOD= 0.04-0.4 ng/ml) method was developed for the detection and quantification of monocarboxylic and dicarboxylic acids (C3 -C10) by GC-MS. These compounds exist in trace amount as essential components of secondary organic aerosols i.e. they are important constituents of atmospheric aerosols. Membrane extraction technique was utilized for selective enrichment (1-4300 times) of

Quasi-governmental organisations - who is responsible in Laval?

I Laval målet så höll Domstolen fast att fackförbund ska hållas ansvariga för överträdelser av EU-rätten i form av blockering av den fria rörelsen för tjänster. Den här uppsatsen har som mål att undersöka det juridiska ansvaret för fackförbund och andra organisationer som är skilda från staten och som kan utöva statsliknande krafter – det jag kallar semi-statliga organisationer. De utövar vid tillIn the Laval case the Court set firm that trade unions should be held responsible for transgressions of EU law in the form of obstructing the freedom to provide services. This paper has the aim to investigate the legal responsibility of trade unions and other organisations separate from the state that can still wield state-like powers – what I call quasi-governmental organisations. They wield the

Present and prediction of China's OFDI compared with neighboring economies

China’s economic reform has opened fresh flood into global market and its recent performance in overseas investment attracts world attention. Through a comparison in motivation, location choice and market entry mode with other Asian economies, as well as theoretical explanations from institutional perspective, this study intends to discover their similarities and differences, thus how unique China

The effects of land and enterprise ownership on child labor: evidence from Mexican households

Significant amount of studies have found evidence on the effects of land ownership on child labor suggesting that land-rich households tend to employ their children more than land-poor households, this phenomenon was labeled as “the wealth paradox”. In this study we include enterprise ownership in the empirical analysis to investigate the effect of ownership and the size of such assets on child la

Optimal Tempererad Asfalt - OTA - en undersökning av asfalt med Sasobit

The concept of OptimalTempered Asphalt, OTA, stands for the best temperature all aspects considered for the bitumen and the manufacturing process as well as the end-product. This is achieved in various ways using additives, choice of manufacturing procedure and changing mixture of asphalt. This bachelor thesis is a study of the effects the additive Sasobit has on bitumen and asphalt from an OTA pe

Ekosystemtjänster från urbana grönytor – en systemstudie med fokus på kollagring och biobränsleproduktion i Lunds kommun

Urbaniseringen sker idag i snabb takt, men genom bebyggelseförtätning kan städernas utbredningshastighet avta. Behovet av att förtäta medför dock att urbana grönytor riskerar att få låg prioritet i stadsplaneringen om inte deras värden är tillräckligt tydliga. Syftet med denna studie är att tydliggöra värdet på de urbana grönytorna i Lunds kommun, samt att visa på potentialen att höja detta värde.Urbanization is a major driver of land-use change but the urban sprawl can be decreased by the densification of cities. On the other hand densification poses a threat to the urban green spaces; areas that have a high delivery of ecosystem services are essential to a high-quality living environment. The aim of this thesis is to illuminate the benefits of urban green space to raise their importance

Användandet av böcker

Thanks to the technical development, how people read text has changed drastically compared to what it used to be before. Today people don’t read books only, they also read on their mobile phones and on their computers. However, you can still see people with a physical book or books out in public; for example on a train, at a station or a library. It is also true that visual material such as advert

Wage Premiums on Education and the Increased Female University Enrollment Rate in Sweden 1970-1990

Before 1977 more men than women enrolled in university education in Sweden. The female enrollment rate started to increased compare to male in 1973 and in 1977 it surpassed the male enrollment rate. Between 1978 and 1990 women remained at a stable level of c.60% of the newly enrolled students. The years 1970-1990 also represents the time period when women greatly expanded their participation in th

Indigenous Peoples – A Hinder to Development?: The Right to Prior Consultation in Colombia and Peru

The thesis deals with the following question: Do the national legislation initiatives of Colombia and Peru, aiming at protecting the Indigenous Peoples’ right to land through their right to be consulted prior to any measures that may affect their lives and lands, reach the internationally set standards that these countries have committed to? The thesis concludes that the term Indigenous Peoples

Default Risk of Treasury Securities

The short-term paper-bill spread is studied and emphasis is put on default risk premia exclusively. An event study analysis is conducted and enhanced by independent quantitative methods. The U.S. money market is exhaustively analyzed throughout the recent global financial crisis. An extension of previous research shows how the market treats Treasury securities in severe times. Empirical results su

Consumer Participation in FMCG Crowdsourcing Contests

Thesis purpose: The purpose of this study is to contribute to the existing literature on co-creation, specifically regarding the phenomenon of consumer participation in crowdsourcing contests. By taking a consumer perspective, it is our ambition to improve the conceptualization of the phenomenon of participants motives, experiences, attitudes and feelings, in general and related to the brand, in

Att låta föremålen komma ur sina glasmontrar - En studie kring utställningen "Jordens Folk" på Danmarks Nationalmuseum

In this essay I analyze the exhibition ”Peoples of the earth”. In order to do this I have asked questions that look into the intentions of the exhibition, the experience of the visitor and the future changes that the ethnographic department is working towards. The methodology used to study these questions are my own experiences from the exhibition, an interview with museum curator Mille Gabrie

Making Business Sustainable – Closing the gap between doing good and making money

Purpose: The purpose of the project is to create a standardized assessment tool for evaluating an organization’s maturity and performance in efforts concerning of sustainability work. Method: The work process of creating the assessment tool has gone from being explorative in the initial phase of creating a theoretical framework to abductive when creating the tool. The theoretical data was collecte

Riskhantering i spannmålsodling

Syftet med studien är att undersöka möjligheter för svenska lantbrukare att hantera risker som påverkar gårdens ekonomiska resultat. Frågeställningen avser att spegla hur spannmålsodlaren utifrån risk- och produktionspreferens kan hantera riskfaktorer för att maximera sin nytta gällande ekonomisk avkastning. Dessa riskfaktorer kan delas in i två huvudgrupper: produktionsrisker och marknadsrisker,