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Comprehensive characterization of neutral and polar lipids of buttermilk from different sources and its milk fat globule membrane isolates

Buttermilk (BM) has recently received much attention as a source of milk fat globule membrane (MFGM) due to its high polar lipid (PL) content, which gives it functional properties and health benefits. Nevertheless BM can be obtained from two different technological processes, i) the BM from the butter oil industry (BM1) and ii) BM from the butter manufacture (BM2). Neutral lipids (NL) and PL chara

Buttermilk and Krill Oil Phospholipids Improve Hippocampal Insulin Resistance and Synaptic Signaling in Aged Rats

Impaired glucose metabolism and mitochondrial decay greatly increase with age, when cognitive decline becomes rampant. No pharmacological or dietary intervention has proven effective, but proper diet and lifestyle do postpone the onset of neurodegeneration and some nutrients are being investigated. We studied insulin signaling, mitochondrial activity and biogenesis, and synaptic signaling in the h

Modulation of miRNA expression in aged rat hippocampus by buttermilk and krill oil

The increasing incidence of age-induced cognitive decline justifies the search for complementary ways of prevention or delay. We studied the effects of concentrates of phospholipids, sphingolipids, and/or 3-n fatty acids on the expression of genes or miRNAs related to synaptic activity and/or neurodegeneration, in the hippocampus of aged Wistar rats following a 3-month supplementation. The combina

Pedobacter lusitanus sp. nov., isolated from sludge of a deactivated uranium mine

Strain NL19T is a Gram-stain-negative, aerobic bacterium that was isolated from sludge of a deactivated uranium mine in Portugal. 16S rRNA gene sequence analysis revealed that strain NL19T is a member of the genus Pedobacter and closely related to the strains Pedobacter himalayensis MTCC 6384T, Pedobacter cryoconitis DSM 14825T, Pedobacter westerhofensis DSM 19036T and Pedobacter hartonius DSM 190

Relevance of dietary glycerophospholipids and sphingolipids to human health

Glycerophospholipids and sphingolipids participate in a variety of indispensable metabolic, neurological, and intracellular signaling processes. In this didactic paper we review the biological roles of phospholipids and try to unravel the precise nature of their putative healthful activities. We conclude that the biological actions of phospholipids activities potentially be nutraceutically exploit

Antioxidant activity of phosphatidyl derivatives of hydroxytyrosol in edible oils

A comparative study of the antioxidant activity of hydroxytyrosol (HT) and phosphatidyl derivatives of hydroxytyrosol (PHT) added at increasing concentrations to diverse edible oils (lard oil, refined olive oil, and diacylglycerol-rich oil) was performed. Antioxidant activity index was estimated as the ratio of induction time in presence of the compounds to induction time in their absence, after o

The emerging alliance of sphingosine-1-phosphate signaling and immune cells: from basic mechanisms to implications in hypertension.

The immune system plays a considerable role in hypertension. In particular, T-lymphocytes are recognized as important players in its pathogenesis. Despite substantial experimental efforts, the molecular mechanisms underlying the nature of T-cell activation contributing to an onset of hypertension or disease perpetuation are still elusive. Amongst other cell types, lymphocytes express distinct prof

Extracellular and intracellular calcium sources mediating contractile responses of smooth muscle in bovine ovarian follicle and ovarian artery

The relative importance of extracellular and intracellular calcium sources mediating smooth muscle contraction in ovarian follicle and ovarian artery was assessed in experiments on the influence of nifedipine, D-600, amrinone, diethylstilbestrol (DES), lanthanum and/or calcium removal on contractions induced by K+ depolarization, by noradrenaline, histamine and acetylcholine. The K+-induced respon

Is serotonin involved in the ovulatory process of the rat ovary perfused in vitro?

The presence of 5‐HT (serotonin) in ovarian tissue and its varying concentrations during the oestrous cycle suggests that it takes part in ovarian function and in the ovulatory process as one of several mediators of the inflammatory‐type reaction preceding follicular rupture. With the aid of a recirculating perfusion model, in which the central stimulatory action of 5‐HT was avoided, its direct ov

Fundamental limits on low-temperature quantum thermometry with finite resolution

While the ability to measure low temperatures accurately in quantum systems is important in a wide range of experiments, the possibilities and the fundamental limits of quantum thermometry are not yet fully understood theoretically. Here we develop a general approach to low-temperature quantum thermometry, taking into account restrictions arising not only from the sample but also from the measurem

Autonomous conversion of information to work in quantum dots

We consider an autonomous implementation of Maxwell's demon in a quantum dot architecture acting on a system without changing its number of particles or its energy. As in the original thought experiment, only the second law of thermodynamics is seemingly violated when disregarding the demon. The autonomous architecture allows us to compare descriptions in terms of information to a more traditional

Anti-windup scheme for networked proportional-integral control

We propose an anti-windup scheme for a class of control problems. This class, includes networked systems, where each node contains a subsystem and each edge comprise a control action. The networked anti-windup control system is proposed to address the issues caused by integrator state saturation. We show that the suggested control scheme is input-output stable. Furthermore, we provide a numerical

Measuring next of kin’s experience of participation in the care of older people in nursing homes

Background Lack of conceptual clarity and measurement methods have led to underdeveloped efforts to measure experience of participation in care by next of kin to older people in nursing homes. Objective We sought to assess the measurement properties of items aimed at operationalizing participation in care by next of kin, applied in nursing homes. Methods A total of 37 items operationalizing partic

Local Synchronization of Two DC/AC Converters Via Matching Control

We address the problem of local synchronization of two DC/AC converters connected via a RL line in closed-loop with machine matching control by pursuing a novel approach for the assessment of small-signal stability. Our method is defined using an oblique projection. We use this Lyapunov function to obtain a local stability certificate in the neighborhood of a well-defined set of equilibria charact

Game-Theoretic Network Bandwidth Distribution for Self-Adaptive Cameras

Devices sharing a network compete for bandwidth, being able to transmit only a limited amount of data. This is for example the case with a network of cameras, that should record and transmit video streams to a monitor node for video surveillance. Adaptive cameras can reduce the quality of their video, thereby increasing the frame compression, to limit network congestion. In this paper, we exploit

Gendering Objects at the V&A and Vasa Museums

This article presents two case studies, which are the result of the application of a gendered interpretative tool to the collections at the Victoria & Albert Museum (London) and the Vasa Museum (Stockholm). Objects and their gendered narratives within the museums’ collections were researched across their lifecycle, from commission and manufacture to consumption and display in a museum setting.

Thinking with Performance : Research-Based Aesthetics in Times of Conflict and Crisis

Thinking with Performance: Research-Based Aesthetics in Times of Conflict and Crisis is an artistic research project in which I examine how to critically think with performance. My main thesis is that research-based performance uses research to respond to conflict and crisis and to create spaces for thinking where artist and audience can reflect on the represented material. As such the research-ba

Reclaim Challenge : Rethinking the Critical Impact of an Education of Performance Art in Denmark

As the Danish National School of Performing Arts merged nine schools into one institution, the momentum for establishing a national, state-funded education in performance art was missed and the continuation of “traditional” profiles within performing arts education was kept. As such, the future of performance art can be seen as a kind of “supplementary technique” to otherwise acting- and text-base

Look-Locker FAIR TrueFISP for arterial spin labelling on mouse at 9.4 T

Pulsed arterial spin labelling remains a non-invasive and highly used method for the study of rodent cerebral blood flow (CBF). Flow-sensitive alternating inversion recovery (FAIR) is one of the most commonly used MR-sequences for this purpose and exists with many different strategies to record the images. This study investigates Look-Locker (LL) TrueFISP readout for FAIR as an alternative to the