This chapter examines the success and failure factors related to the implementation of an Idea Management System (IMS) to manage employees’ ideas about future products and services. The authors discuss an illustrative case involving two different geographically separated sites – South and North – belonging to the same Swedish subsidiary of a global IT firm. The introduction of IMS was a success at

Background: The standard treatment of hypothyroidism is levothyroxine (LT-4). However, there are several controversies regarding treatment of hypothyroid patients. Aim: To investigate the Swedish endocrinologists’ use of thyroid hormones in hypothyroid and euthyroid individuals. Methods: Physician members of the Swedish Endocrine Society (SEF) were invited by e-mail to participate in an online sur

INTRODUCTION: Tobacco is still one of the single most important risk factors among the lifestyle habits that cause morbidity and mortality in humans. Furthermore, tobacco has a heavy social gradient, as the consequences are even worse among disadvantaged and vulnerable groups. To reduce tobacco-related inequity in health, those most in need should be offered the most effective tobacco cessation in

Context. Hot subdwarfs experienced strong mass loss on the red giant branch (RGB) and are now hot and small He-burning objects. These stars constitute excellent opportunities for addressing the question of the evolution of exoplanetary systems directly after the RGB phase of evolution.Aims. In this project we aim to perform a transit survey in all available light curves of hot subdwarfs from space

Anaplastic thyroid carcinoma (ATC) is a lethal malignancy characterized by poor response to conventional therapies. Whole-genome sequencing (WGS) analyses of this tumor type are limited, and we therefore interrogated eight ATCs using WGS and RNA sequencing. Five out of eight cases (63%) displayed cyclin-dependent kinase inhibitor 2A (CDKN2A) abnormalities, either copy number loss (n = 4) or trunca

Purpose: Biological and/or physical assays for retrospective dosimetry are valuable tools to recover the exposure situation and to aid medical decision making. To further validate and improve such biological and physical assays, in 2019, EURADOS Working Group 10 and RENEB performed a field exercise in Lund, Sweden, to simulate various real-life exposure scenarios. Materials and methods: For the di

The UK Athena SWAN (AS) Charter was extended to Irish Higher Education Institutions (HEIs) in 2015 to provide a catalyst for change towards gender equality and to transform institutional cultures, through AS Gender Action Plans. This paper charts: the journey of Athena SWAN to Ireland; its rate of adoption by Irish HEIs; and its impact on the sector. Drawing upon the perspective and contribution o

Mantle cell lymphoma (MCL) is an aggressive B-cell neoplasm that follows a heterogeneous clinical course. Recurrent mutations have been described, but their applicability in the clinical setting is currently limited. The main reasons are challenges in the sequencing of DNA retrieved from formalin-fixed tissue commonly used for tissue collection in clinical biobanks. In this study, we sequenced 77

This paper presents a new hybrid model, called ENN-SA, for spatiotemporal drought prediction. In ENN-SA, an Elman neural network (ENN) is conjugated with simulated annealing (SA) optimization and support vector machine (SVM) classification algorithms for the standardized precipitation index (SPI) modeling at multiple stations. The proposed model could be applied to predict SPI at different time sc

The invasive yellow-fever mosquito Aedes aegypti preferentially feeds on human blood. A new study finds that human-biting in this important disease vector might just be an unfortunate side effect of breeding in human-stored water.

In the framework of the ATTRACT-uRANIA project, funded by the European Community, we are developing an innovative neutron imaging detector based on micro-Resistive WELL (μ-RWELL) technology. The μ-RWELL, based on the resistive detector concept, ensuring an efficient spark quenching mechanism, is a highly reliable device. It is composed by two main elements: A readout-PCB and a cathode. The amplifi

Background: Prior research has established evidence for self-determination enhancement as a promising intervention for youth transitioning from out-of-home care. Understanding how participants in these prior trials compare to adolescents in target contexts may inform practice by highlighting the extent to which such models are expected to benefit young people. Objective: To assess the extent to wh

CRISPR är en revolutionerande teknik som möjliggör effektiv redigering av DNA.Kliniska studier med CRISPR-baserade terapier för blodsjukdomar och cancer pågår redan.Framtida tillämpningar av CRISPR kan förväntas bli breda men förutsätter etiska, juridiska och hälsoekonomiska överväganden.

Plasma concentrations of many cardiovascular and inflammatory proteins are altered after ST-elevation myocardial infarction (STEMI) and may provide prognostic information. We conducted a large-scale proteomic analysis in patients with STEMI, correlating protein levels to infarct size and left ventricular ejection fraction (LVEF) determined with cardiac magnetic resonance imaging. We analysed 131 c

Purpose: To explore work related and personal facilitators and barriers for return to work (RTW) and stay at work after stroke. Materials and methods: Twenty individuals post-stroke (median age 52 years; seven women) were interviewed in focus groups. Data were analyzed by using qualitative content analysis. Results: An overall theme “Work conditions, support and changed personal priorities influen

An overview of housing assessment tools developed or adapted for research use in East and Southeast Asia is currently lacking. A scoping review was conducted to address this knowledge gap. PubMed, Web of Science and CINAHL were searched for relevant scientific literature, and 22 articles were selected. Besides study-specific checklists, two assessment tools validated for use in Asia and three vali

The chronology of post-last Glacial Maximum dceglaciation in the northern Antarctic Peninsula region is discussed. It is concluded that, contrary to what was earlier believed, the deglaciation process here was largely out-of-phase with that in the Northern Hemisphere. Although, for global eustatic reasons, the marine-based glaciers may have retreated simultaneously with ice-melting in the Northern

We investigate various performance indicators of ten leading journals in the field of Agricultural Economics and Policy over the period from 2000 to 2020. More specifically, we combine various data sources to derive a coherent record of indicators including acceptance rates, times between submission and first response and impact factors. We show that, for the discipline at large, the turn-around t