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AIM:To study the interactions between human gastric carcinoma cell (HGCC) and human vascular endothelial cell (HVEC), and the role of KDR in these interactions. METHODS:Antisense oligodexynucleotide(ASODN) specific to KDR gene was devised and added to the culture medium of HGCC and HVEC. After the action of ASODN, the proliferation of two cells was measured by MTT method. The role of KDR in regula

Aim To investigate the association between psychosocial conditions at work, unemployment and self-reported psychological health. Methods A cross-sectional postal questionnaire for the 2000 public health survey in Scania was administered to both working and unemployed people aged 18–64 years. Logistic regression models were used to investigate the association between psychosocial factors at work/u

In recent years, small businesses have received much attention from policy makers and researchers, in that these businesses are considered important for economic growth and job creation. At the same time small businesses are assumed to face major problems in securing long-term external finance, which is regarded as restraining their development and growth. Small business managers are assumed to us

According to our recent results the alveolar surface is formed by a coherent phase, not a monolayer as has been assumed earlier. This surface phase is a tetragonal organization of the lipid bilayer which seems to follow the CLP minimal surface structure. As lipid bilayers at cooling will undergo a transition from the liquid-crystalline type of structure into a solid state structure, we have follow

Structural properties of encapsidated flexible polyelectrolytes in viral capsids with dodecahedral charge distribution have been investigated by Monte Carlo simulations using a coarse-grained model. Several capsid charge distributions ranging from a homogeneous surface charge distribution (lambda=0) to a complete dodecahedral distribution (lambda=1) at constant total capsid charge and fixed radial

At night the Namib Desert spider Leucorchestris arenicola performs long-distance homing across its sand dune habitat. By disabling all or pairs of the spiders' eight eyes we found that homing ability was severely reduced when vision was fully abolished. Vision, therefore, seems to play a key role in the nocturnal navigational performances of L. arenicola. After excluding two or three pairs of eyes

Today there is ample evidence that the Cognitive Interview (CI) enhances witnesses' memory. However, less is known about how the CI affects eyewitnesses' confidence. To address this shortcoming we conducted a study analyzing how realism in confidence was affected by the CI. All participants (n = 79) were first shown a filmed kidnapping. After 2 weeks we interviewed one-third of the participants ac

A fast and stable numerical algorithm is presented for the elastostatic problem of a linearly elastic plane with holes, loaded at infinity. The holes are free of stress. The algorithm is based on an integral equation which is intended as an alternative to the classic Sherman–Lauricella equation. The new scheme is argued to be both simpler and more reliable than schemes based on the Sherman–Laurice

As negotiations on the post-2012 climate regime are now taking off, it is time to look back and assess the experiences of the clean development mechanism (CDM) to this date. The CDM has been subject to extensive discussion in academic literature during the last few years, and this article reviews that literature in order to sum up its main themes. A common assessment is that the current structure

We present a simple and controllable method for fabricating nano-apertures in a metal film using polystyrene nano-spheres as masks during the metal evaporation. We show how the processing conditions used during deposition of the spheres such as spin velocity, nano-sphere concentration and a reduction of the surface tension interplay and control the distribution of spheres. The fabrication method i

Information storage in neural circuits depends on activity-dependent alterations in synaptic weights, such as long-term potentiation (LTP) and long-term depression (LTD). Bidirectional synaptic plasticity endows synapses with mechanisms for rapid reversibility, but it remains unclear how it correlates with reversibility in behavioral learning and whether there is a universal synaptic memory mechan

Objective. To explore situations in which parents with an ill child consult a physician and to identify trigger factors for consultation. Design and settings. Qualitative interviews with parents of young children. Parents were asked to describe the situation in which the decision to contact the physician was made. Subjects. A total of 20 families selected from a birth cohort from Frederiksborg Cou

The next generation of telescopes, the Extremely Large Telescopes (ELTs), will have a multitude Of control loops to maintain nearly diffraction-limited performance in the presence of atmospheric turbulence and external disturbances, for instance from wind. Integrated simulation models combining structural and optical modeling together with control system modeling are efficient tools for prediction

Macroporous monolithic cryogels made from poly(vinyl alcohol) (PVA) with degree of saponification 87.7% have been prepared using a crosslinking reaction with glutaralclehyde under acidic conditions at subzero ternperatures. The porous structure of the monolithic cryogels from PVA (cryoPVA), analyzed using optical microscopy, scarinina electron microscopy, and environmental scanning electron micros

Insertions and deletions of nucleotides in the genes encoding the variable domains of antibodies are natural components of the hypermutation process, which may expand the available repertoire of hypervariable loop lengths and conformations. Although insertion of amino acids has also been utilized in antibody engineering, little is known about the functional consequences of such modifications. To i

Background: The time course of infarct evolution, i.e. how fast myocardial infarction (MI) develops during coronary artery occlusion, is well known for several species, whereas no direct evidence exists on the evolution of MI size normalized to myocardium at risk (MaR) in man. Despite the lack of direct evidence, current literature often refers to the "golden hour" as the time during which myocard

With its focus on gender, the aim of this study was to investigate the role of work locus of control (WLC) for job satisfaction and health in the context of occupational stress. Data were collected from 281 women and men at both managerial and non-managerial level in a Swedish telecom company. As hypothesized, external WLC was positively related to stressors and symptoms of ill-health, whereas it