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Fabrication of Si-based nanoimprint stamps with sub-20 nm features

We present two alternative methods for fabrication of nanoimprint lithography stamps in SiO2 with sub-20 nm features: (a) optimized electron beam lithography (EBL) and lift-off patterning of a 15-nm thick Cr mask, and (b) aerosol deposition of W particles in the 20-nm size range. In both cases, the pattern transfer into SiO2 was performed using reactive ion etching (RIE) with CHF3 as etch gas. In

Algebraic Properties of Multilinear Constraints

In this paper the different algebraic varieties that can be generated from multiple view geometry with uncalibrated cameras have been investigated. The natural descriptor, V-n, to work with is the image of P-3 in P-2 x P-2 x ... x P-2 under a corresponding product of projections, (A(1) x A(2) x ... x A(m)). Another descriptor, the variety V-b, is the one generated by all bilinear forms between pai

Computation of combined turbulent convective and impingement heat transfer

Impingement and forced convection are preferable methods for cooling gas turbine components. However, influences of various design parameters like crossflow and surface enlargements (like ribs) are not well understood. Thus there is a request for reliable and cost effective computational prediction methods, due to the experimental difficulties. such methods could be based on the numerical solution

A photoelectron spectroscopy and photon stimulated desorption study of H2O on Si(100) 2×1

We have studied H2O adsorption on the Si(100) surface using photoelectron spectroscopy to record Si valence bands and Si 2p core level spectra; and photon stimulated desorption to record Si 2p edge total electron yield and H + -ion yield spectra. We assign the valence-band H2O induced peaks at EB=6.3 and 11.2 eV to the Si–OH and to the O–H bonds, respectively. The H2O dosed Si 2p core level spectr

Chondromodulin I Is Dispensable during Enchondral Ossification and Eye Development.

Chondromodulin I (chm-I), a type II transmembrane protein, is highly expressed in the avascular zones of cartilage but is downregulated in the hypertrophic region, which is invaded by blood vessels during enchondral ossification. In vitro and in vivo assays with the purified protein have shown chondrocyte-modulating and angiogenesis-inhibiting functions. To investigate chm-I function in vivo, we g

Clinical and biological importance of cytogenetic abnormalities in childhood and adult acute lymphoblastic leukemia

Among the approximately 7,000 cytogenetically abnormal childhood and adult B- and T-lineage acute lymphoblastic leukemias (ALL) published to date, numerous recurring chromosomal aberrations and abnormality patterns have been identified, and it has been clearly shown that the cytogenetic features often correlate closely with specific morphologic, immunophenotypic, and clinical parameters. Thus, kar

A virtual-accelerator-based verification of a Monte Carlo dose calculation algorithm for electron beam treatment planning in clinical situations.

Background and purpose The introduction of Monte Carlo (MC) techniques for treatment planning and also for verification purposes will have considerable impact on the radiation therapy planning process. The aim of this work was to use a virtual accelerator to study the performance of a MC-based electron dose calculation algorithm, implemented in a commercial treatment planning system. Methods The

Structural aspects of signal transduction in B-cells

Signal transduction in hematopoietic cells is a highly specific process. The stimulation of B cell receptor following antigen binding triggers, as a first step, phosphorylation of the cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). Src family tyrosine kinases Blk, Fyn, Lck, and Lyn as well as spleen kinase, Syk, are activated to transmit the signal further. In this review the

A repetitive sequence of Epstein-Barr virus nuclear antigen 6 comprises overlapping T cell epitopes which induce HLA-DR-restricted CD4(+) T lymphocytes

Most human adults carry the Epstein-Barr virus (EBV) and develop immunological memory against the structural and the virus-encoded cellular proteins. The EBV nuclear antigen 6 (EBNA6) elicits cytotoxic T cell responses and it also maintains a persistent antibody response. The majority of sera from EBV-seropositive individuals reacts with a synthetic peptide, p63, comprising 21 amino acids of a rep

Network analysis of the state space of discrete dynamical systems

We study networks representing the dynamics of elementary 1D cellular automata (CA) on finite lattices. We analyze scaling behaviors of both local and global network properties as a function of system size. The scaling of the largest node in-degree is obtained analytically for a variety of CA including rules 22, 54, and 110. We further define the path diversity as a global network measure. The coa

Rayleigh mixture model-based hidden Markov modeling and estimation of noise in noisy speech signals

In this paper, we propose a new statistical model for noise periodogram modeling and estimation. The proposed model is a hidden Markov model (HMM) with a Rayleigh mixture model (RMM) in each state. For this new model, we derive an expectation-maxinuzation (EM) training algorithm and a minimum meansquare error (NIMSE) noise periodogram estimator. It is shown that when compared to the Gaussian mixtu

Statistical methods for monitoring the relationship between the IFCC reference measurement procedure for hemoglobin A(1c) and the designated comparison methods in the United States, Japan, and Sweden

BACKGROUND: The American Diabetes Association (ADA)/European Association for the Study of Diabetes (EASD)/International Diabetes Federation GDFAFCC Consensus Statement on the worldwide standardization of HbA(1c) states that"...[HbA(1c)] results are to be reported world-wide in IFCC units...and derived NGSP units...,using the IFCC-NGSP master equation." METHODS: We describe statistical methods to e

Compass orientation and possible migration routes of passerine birds at high arctic latitudes

The use of celestial or geomagnetic orientation cues can lead migratory birds along different migration routes during the migratory journeys, e.g. great circle routes (approximate), geographic or magnetic loxodromes. Orientation cage experiments have indicated that migrating birds are capable of detecting magnetic compass information at high northern latitudes even at very steep angles of inclinat

Intraspecific competition in tadpoles of Rana arvalis: does it matter in nature? A field experiment

Tadpole growth and development are easily affected by intraspecific competition in tank experiments, provided treatment density is sufficiently high. Is this a phenomenon also observed in nature? A pond was divided into four tadpole-proof sections. Each year for 8 years, all spawn laid by moorfrogs (Rana arvalis) in this pond was relocated to create relative spawn and tadpole densities of 1:4:1:4.

Laboratory and field test of a sampling method for characterization of combustion aerosols at high temperatures

The objective of this study was to design and experimentally examine a sampling method for high-temperature aerosols from biomass combustion, in which nucleation and condensation from fly ash forming vapors is controlled. The sampling method includes a high-temperature probe in which the hot gas is diluted and then cooled. Laboratory results from sampling a model aerosol with known concentrations