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Popular Abstract in Swedish Hjärt- och kärlsjukdomar är den främsta orsaken till en för tidig död för både män och kvinnor i dagens industrialiserade samhällen. I det akuta förloppet av dessa sjukdomar spelar blodplätten (trombocyten) en viktig roll då den är inblandad i bildandet av blodproppar. Den kärnlösa och kortlivade trombocytens roll är vanligen en annan och central i läkningsprosessen av Platelets are central for the primary haemostatis. The platelet has surface bound receptors that are vital for the platelet activation. One of these receptors, the purinergic ADP-activated G-protein coupled receptor (GPCR) P2Y12 is a key receptor for platelet activation, and thus for thrombus formation, which makes P2Y12 a target in pharmaceutical antiplatelet therapies. As a complement during rev

1/f noise is studied in dual-gated InAs nanowire transistors consisting of an omega top gate with high-k atomic layer deposited dielectric and silicon dioxide to substrate back gate. Noise spectra at varying gate bias combinations are compared from devices with differing top-gate lengths to separate the noise contributions of the top-gated channel from the ungated access portion, including the met

Popular Abstract in Swedish Rökning är den vanligaste och viktigaste riskfaktorn för att få sänkt lungfunktion. Kroniskt obstruktiv lungsjukdom (KOL) orsakas oftast av rökning, men drabbar inte alla som röker. Det är en sjukdom som ger försämrad lungfunktion och de som drabbas upplever andfåddhet och hosta, ibland med slemproduktion. För att ställa diagnosen KOL krävs att lungfunktionen har undersSmoking is the most common and important risk factor for reduced lung function. Chronic Obstructive Pulmonary Disease (COPD) affects mainly smokers and is characterized by airflow obstruction, assessed using one of two major diagnostic spirometric criteria. Aspects of lung function besides spirometry in smokers fulfilling none, either or both of the spirometric criteria for COPD are not well known

Background Increased levels of thyroglobulin (Tg) and thyroid-stimulating hormone (TSH) are associated with differentiated thyroid carcinoma (TC) risk, but strong epidemiological evidence is lacking. Methods Three hundred fifty-seven incident TC case patients (n = 300 women and 57 men; mean age at blood collection = 51.5 years) were identified in the EPIC cohort study and matched with 2 (women) or

Objectives To determine the effect of an ultrasound training course on the performance of pattern recognition when used by less experienced examiners and to compare the performance of pattern recognition, a logistic regression model and a scoring system to estimate the risk of malignancy between examiners with different levels of experience. Methods Using ultrasound images of selected adnexal mass

Background: There is a controversy regarding the existence of a socio-economic gradient for cerebral palsy. Perinatal emergencies and preterm birth increase the risk for the offspring to develop cerebral palsy. The aim of this study was to investigate the association of socio-economic indicators with cerebral palsy (CP) and the role of perinatal health as mediator of this association. Methods: Reg

This article about Federico Fellini’s Amarcord (1973) and Ingmar Bergman’s Fanny and Alexander (1982) concerns one aspect of the directors’ childhood memories, namely how authoritarian institutions are used to disrupt otherwise fairly idyllic and nostalgic lives and worlds. The films blend detailed memories with playful fantasies, combine experiences of the directors’ alter ego Titta and Alexander

In this paper a data set of 716 radiocarbon dates from the South-Swedish Upland is presented. The dated material is charcoal found beneath clearance cairns, which originates from agricultural land clearance by fire. The chronological distribution of the calibrated dates, presented as summed probability, is interpreted in terms of agricultural fluctuations as well as long-term changes in human popu

We studied the heating efficiency of an electrically heated vest (EHV), its relationship to the microclimate temperature distribution in a three-layer clothing ensemble and the effect of an EHV on the clothing’s total thermal insulation by both theoretical analysis and thermal manikin measurements. The heat losses at different ambient conditions and heating states were recorded and the heating eff

Systematic studies of global observables in different collision systems are indispensable for mapping the QCD phase diagram. Fluctuations in these quantities can provide fundamental information relevant for the phase transitions. The following global observables relevant to critical behavior are studied: the longitudinal density correlation, K to π and p to π fluctuations, and the constituent quar

I denna artikel analyseras möteskulturer och mötesstrider mellan olika professionella i ungdomsvården, samt det starka engagemang som ägnas åt dessa möten. Artikeln bygger på en studie av ett samverkansprojekt i ungdomsvården där ett antal samordnare anställdes. Det visade sig att dessa efter hand kom att upprätthålla en administrativ hållning gentemot varandra, vilket satte det direkt arbetet medThis article concerns a large evaluation of a project concerning Swedish juvenile care. The project were set up as a “care-chain” involving various authorities, and a number of coordinators were employed to facilitate youngsters’ “after-care” when they had left the special approved homes of The National Board of Institutional Care. Even though the original goals of the project stated that the coor

Although food crop yields per hectare have generally been increasing in Cameroon since 1961, the food price crisis of 2008 and the ensuing social unrest and fatalities raised concerns about the country's ability to meet the food needs of its population. This study examines the country's potential for increasing crop yields and food production to meet this food security challenge. Fuzzy set theory

The problem of fundamental frequency estimation is considered in the context of signals where the frequencies of the harmonics are not exact integer multiples of a fundamental frequency. This frequently occurs in audio signals produced by, for example, stiff-stringed musical instruments, and is sometimes referred to as inharmonicity. We derive a novel robust method based on the subspace orthogonal

The results of a search for pair production of light top squarks are presented, using 4.7 fb(-1) of root s = 7 TeV proton-proton collisions collected with the ATLAS detector at the Large Hadron Collider. This search targets top squarks with masses similar to, or lighter than, the top quark mass. Final states containing exclusively one or two leptons (e, mu), large missing transverse momentum, ligh

Popular Abstract in Swedish Sepsis, blodförgiftning är en systemisk inflammatorisk reaktion syndrom vid en lokal eller systemisk infektion som leder till överproduktion av proinflammatoriska cytokiner och det ultimata misslyckandet av flera organsystem. Sepsis är ett potentiellt allvarligt och komplicerat kliniskt syndrom samt är en av de vanligaste orsakerna till döden på intensivvårdsavdelningarSepsis is a systemic inflammatory response syndrome to a localized or systemic infection that leads to the over production of proinflammatory cytokines and the ultimate failure of multiple organ systems. However, little is known about the potential role of Rac1 in controlling sepsis-induced intracellular signaling pathways. We hypothesized that Rac1 might be involved in sepsis mediated signaling p