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Identification PMS1 and PMS2 as potential meiotic substrates of CDK2 activity

Cyclin dependent-kinase 2 (CDK2) plays important functions during the mitotic cell cycle and also facilitates several key events during germ cell development. The majority of CDK2's known meiotic functions occur during prophase of the first meiotic division. Here, CDK2 is involved in the regulation of meiotic transcription, the pairing of homologous chromosomes, and the maturation of meiotic cross

Low temperature atomic hydrogen annealing of InGaAs MOSFETs

Recent work showing a strong quality improvement of the Si/SiO2 material system by low temperature atomic hydrogen annealing (AHA), and the fact that III-V semiconductors outperform Si in many applications makes the investigation of AHA on III-V/high-k interfaces to a very interesting topic. In this work, the potential of AHA as a low temperature annealing treatment of InGaAs metal-oxide-semicondu

Characterization of land plant-specific proteins required for mitochondrial translation initiation

Plant mitochondria produce the majority of adenosine triphosphate (ATP) – the cellular energy currency for metabolic reactions needed for plant growth, development, and maintenance. Despite a relatively thorough understanding of basic mitochondrial functions, many mitochondrial proteins and processes remain poorly understood. The aims of this thesis are to i) review and compare the mitochondrial u

Religious Enlightenment in the eighteenth-century Nordic countries : Reason and orthodoxy

This book explores the concept of religious Enlightenment in the Nordic countries during the long eighteenth century. It argues that Lutheran confessional culture became intertwined with Enlightenment ideas and practices in this European region. In the book's three parts, specialist historians explore themes central to students of the early modern era - historical writing, material culture, ecclesThis book explores the concept of religious Enlightenment in the Nordic countries during the long eighteenth century. It argues that Lutheran confessional culture became intertwined with Enlightenment ideas and practices in this European region. In the book's three parts, specialist historians explore themes central to students of the early modern era - historical writing, material culture, eccles

Whose responsibility is it to talk with children and young people about intersex/differences in sex development? : Young people’s, caregivers’ and health professionals’ perspectives

Introduction: Over the past two decades, there has been a shift from concealing diagnoses of sex development from impacted people to the broad principle of age-appropriate disclosure. This change is consistent with children’s rights and with general shifts towards giving children medical information and involving patients in medical decision-making. The present paper examines how health profession

SCA-LDPC: A Code-Based Framework for Key-Recovery Side-Channel Attacks on Post-Quantum Encryption Schemes

Whereas theoretical attacks on standardized crypto primitives rarely lead to actual practical attacks, the situation is different for side-channel attacks. Improvements in the performance of side-channel attacks are of utmost importance.In this paper, we propose a framework to be used in key-recovery side-channel attacks on CCA-secure post-quantum encryption schemes. The basic idea is to construct

Harvesting a Wide Spectral Range of Electronic Coherences with Disordered Quasi-Homo Dimeric Assemblies at Room Temperature

A wide variety of photoinduced electronic coherences are shown to be robust with respect to dephasing in ensembles of quasi-homodimers assembled with sub-nm ligands from colloidal 3 nm CdSe quantum dots (QDs) with controlled 9% size dispersion, both in solution and in solid-state. Coherence periods ranging from 40 to 300 fs are consistently characterized by multidimensional electronic spectroscopy

Parameterstudie av ventilationsbehov för vätgasinstallationer

Vätgas har en tendens att i läcka ut i små mängder i kopplingar samt även diffusera igenom de flesta material. Detta innebär, tillsammans med vätgasens utmanande förbränningsegenskaper, att normalventilation av utrymmen där vätgas hanteras är mycket viktig.I denna rapport presenteras kortfattat en ny metod för dimensionering av normalventilation baserad på multizon‐konceptet där utrymmet delas in

Influence of Sprinklers on the Thermal Exposure of a Tank Exposed to a Hydrogen Jet Flame

A high-pressure tank rupture is a challenging scenario requiring attention in most hydrogen applications. A common cause of rupture is an external fire heating the tank, causing increased internal pressure and/or reduction in the tensile strength of the tank material (with the relevance of each depending on tank material).Most of the available methods for prevention of such ruptures have been deveA high-pressure tank rupture is a challenging scenario requiring attention in most hydrogen applications. A common cause of rupture is an external fire heating the tank, causing increased internal pressure and/or reduction in the tensile strength of the tank material (with the relevance of each depending on tank material).Most of the available methods for prevention of such ruptures have been deve

Surfactant induced gelation of TEMPO-oxidized cellulose nanofibril dispersions probed using small angle neutron scattering

In this work, we studied TEMPO-oxidized cellulose nanofibril (OCNF) suspensions in the presence of diverse surfactants. Using a combination of small angle neutron scattering (SANS) and rheology, we compared the physical properties of the suspensions with their structural behavior. Four surfactants were studied, all with the same hydrophobic tail length but different headgroups: hexaethylene glycol

Cellulose Acetate Microbeads for Controlled Delivery of Essential Micronutrients

The controlled delivery of micronutrients to soil and plants is essential to increase agricultural yields. However, this is today achieved using fossil fuel-derived plastic carriers, posing environmental risks and contributing to global carbon emissions. In this work, a novel and efficient way to prepare biodegradable zinc-impregnated cellulose acetate beads for use as controlled release fertilize

Mix-and-Match Diols: Adjusting Self-Assembly of Micellar Phases in Choline Chloride Eutectics

The common Deep Eutectic Solvent (DES) ‘ethaline’ (1:2 choline chloride:ethylene glycol) was examined here as a basis for the self-assembly of the surfactant dodecyltrimethylammonium bromide (C12TAB). A phase diagram was constructed, showing evidence for a L1 (micellar) phase, confirmed by tensiometry to have a room temperature critical micelle concentration (CMC) of 1.2 wt.%. Small angle neutron

Structure and Properties of "type IV" Lanthanide Nitrate Hydrate:Urea Deep Eutectic Solvents

A series of lanthanide nitrate hydrate:urea "Type IV" deep eutectic solvents (DES; Ln = Ce, Pr, Nd) were prepared and their physical properties measured, showing very high surface tension and density, with low viscosity and glass transition temperatures. Calculated Gordon parameters were similar to water, with lower molecular volumes than "Type III" DES. The LnDES were used as reaction media for

Ibuprofen delivery into and through the skin from novel oxidized cellulose-based gels and conventional topical formulations

The delivery of ibuprofen into and through the skin from novel formulations containing TEMPO-oxidized cellulose nanofibril-based (TOCN) gels was compared to that from two conventional and commercially available products. The gels were evaluated in-vitro (using both silicone membranes, and pig skin) and in-vivo in human volunteers. All gels showed consistent behaviour in a standard in vitro release

Insights into the influence of solvent polarity on the crystallization of poly(ethylene oxide) spin-coated thin films via in situ grazing incidence wide-angle X-ray scattering

Controlling polymer thin-film morphology and crystallinity is crucial for a wide range of applications, particularly in thin-film organic electronic devices. In this work, the crystallization behavior of a model polymer, poly(ethylene oxide) (PEO), during spin-coating is studied. PEO films were spun-cast from solvents possessing different polarities (chloroform, THF, and methanol) and probed via i

Liquid structure of the choline chloride-urea deep eutectic solvent (reline) from neutron diffraction and atomistic modelling

The liquid structure of the archetypal Deep Eutectic Solvent (DES) reline, a 1:2 molar mixture of choline chloride and urea, has been determined at 303 K. This is the first reported liquid-phase neutron diffraction experiment on a cholinium DES. H/D isotopic substitution is used to obtain differential neutron scattering cross sections, and an Empirical Potential Structure Refinement (EPSR) model i

Langmuir monolayers composed of single and double tail sulfobetaine lipids

Hypothesis: Owing to structural similarities between sulfobetaine lipids and phospholipids it should be possible to form stable Langmuir monolayers from long tail sulfobetaines. By modification of the density of lipid tail group (number of carbon chains) it should also be possible to modulate the two-dimensional phase behaviour of these lipids and thereby compare with that of equivalent phospholip