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A multiscale in situ time-resolved study of the nano- to millisecond structural dynamics during protein crystallization

Protein crystallization is key to determining the structure of proteins at atomic resolution. It can occur naturally, including in pathological pathways, for instance with aquaporin and γ-crystallin proteins. A fundamental understanding of the underlying crystallization process is both technologically and biologically relevant. A multitechnique approach is employed here to investigate protein crys

A digital tool for life cycle assessment in construction projects

The building and construction industry is responsible for around 40% of global greenhouse gas emissions, driving the urgent need for new regulations. As such, the life cycle assessment (LCA) methodology has become fundamental for evaluating environmental impacts. Despite the need for digital tools to support environmental performance evaluations, the lack of guidance on developing such tools hindeThe building and construction industry is responsible for around 40% of global greenhouse gas emissions, driving the urgent need for new regulations. As such, the life cycle assessment (LCA) methodology has become fundamental for evaluating environmental impacts. Despite the need for digital tools to support environmental performance evaluations, the lack of guidance on developing such tools hinde

Gender balance and inclusivity lie in the or g anizers’ hands: insights from org anizing the 7th International Induced Polarization Workshop

Our viewpoint highlights the challenges faced by women in the Induced Polarization (IP) community (and elsewhere), particularly the persistent gender imbalance in scientific workshops. This underrepresentation in leadership roles, presentations and discussions reflects broader systemic biases in academia. By sharing the experience of the 7th IP workshop, where the organizing team made deliberate eff

3-D impedance networks simulate complex resistivity spectra of sand-pyrite-water mixtures

Characterizing ore deposits or mining dumps in terms of mineral content and grain size remains a challenge. Since the 1950s the induced polarization (IP) method has been successfully applied in ore prospecting. However, reliably interpreting field survey data requires comprehensive laboratory studies to establish a link between the IP parameters from empirical or phenomenological models and the typ

A systematic meta-review: the relationship between forest structures and biodiversity in deciduous forests.

Human activities in deciduous forests over the past centuries have influenced associated species. To reduce extinction risks and mitigate population declines, there is growing interest in forest conservation and restoration, including initiatives by the European Union (EU). For resulting restoration and conservation practices to succeed, it is essential to know which forest characteristics promote

Genombrott i fuktmätning : Ingjutningsbara och trådlösa RF-prober för betong

Mätning av relativ fuktighet, RF, i betong har tagit ett stort steg framåt med hjälp av trådlösa RF-prober som kan gjutas in direkt från start. I ett nyligen avslutat projekt vid avdelning Byggnadsmaterial vid Lunds tekniska högskola har ett mätsystem för RF i betong utvärderats. En av de största utmaningarna var att säkerställa att proberna klarar ingjutning och att de ger tillförlitliga mätninga

Renovera för hela livet. Det är inte bara en fråga för fastighetsägare.

Bostadskrisen slår mot alla generationer – men lösningarna måste vara långsiktiga och inkludera de behov äldre människor har. Det skriver fyra forskare som är verksamma vid institutionen för hälsovetenskaper vid Lunds universitet och tillhörforskningscentret CASE, Centre for Ageing and Supportive Environments.

Global Distribution and Local Variation of Pre-Rain Green-Up in Tropical Dryland

Pre-rain green-up is a distinctive phenological phenomenon observed in arid and semi-arid regions, featuring the sprouting of plants before the onset of the rainy season. This phenomenon indicates the intricate controls of vegetation phenology other than precipitation, yet its global distribution patterns and underlying causes remain unclear. In this study, we used remotely sensed phenology and ra

Resilience of primary healthcare facilities : Experiences from 16 European countries during the COVID-19 pandemic. A mixed-methods study conducted by EURIPA

Background. The role of primary healthcare (PHC) during a pandemic varies across European countries. The coronavirus disease 2019 (COVID-19) pandemic has altered the working practices of family medicine doctors and impacted the resilience of healthcare systems. Objectives. This study aimed to examine European healthcare system responses to the pandemic, focusing on rural and urban differences. Mat

Antisense-mediated regulation of exon usage in the elastic spring region of Titin modulates sarcomere function

Aims Alternative splicing of Titin (TTN) I-band exons produce protein isoforms with variable size and elasticity, but the mechanisms whereby TTN splice factors regulate exon usage and thereby determining cardiomyocyte passive stiffness and diastolic function, is not well understood. Non-coding RNA transcripts from the antisense strand of protein-coding genes have been shown to regulate alternative

TinyFoA : Memory Efficient Forward-Only Algorithm for On-Device Learning

Forward-only algorithms offer a promising memory-efficient alternative to Backpropagation (BP) for on-device training. However, state-of-the-art forward-only algorithms, e.g., Forward-Forward (FF), still require a substantial amount of memory during the training process, often exceeding the limits of mobile edge and Internet of Things (IoT) devices. At the same time, existing memory-optimization t

X-ray crystallographic and hydrogen deuterium exchange studies confirm alternate kinetic models for homolog insulin monomers

Despite the crucial role of various insulin analogs in achieving satisfactory glycemic control, a comprehensive understanding of their in-solution dynamic mechanisms still holds the potential to further optimize rapid insulin analogs, thus significantly improving the well-being of individuals with Type 1 Diabetes. Here, we employed hydrogen-deuterium exchange mass spectrometry to decipher the mole

Marknadsföring, människor och interaktion

Marknadsföring är så mycket mer än strategier, marknadsundersökningar och reklamkampanjer. Den uppstår i det dagliga samspelet mellan människor. I Marknadsföring, människor och interaktion får vi ett alternativt perspektiv på marknadsföring, bortom den traditionella marketing management-logiken. Genom att utgå från symbolisk interaktionism synliggör författarna hur marknader, konsumenter, produkte

Late Medieval Shipboard Artillery on a Northern European Carvel : Gribshunden (1495)

We present the artillery of a well-preserved late medieval Danish-Norwegian carvel warship, Gribshunden. Probably built in the Netherlands in 1484, the ship served King Hans until sinking in June 1495. Of its original 50 or more guns, elements of 11 have been recovered and digitally recreated, and more remain on the wreck. Investigation of this site provides insights into the development of shipboWe present the artillery of a well-preserved late medieval Danish-Norwegian carvel warship, Gribshunden. Probably built in the Netherlands in 1484, the ship served King Hans until sinking in June 1495. Of its original 50 or more guns, elements of 11 have been recovered and digitally recreated, and more remain on the wreck. Investigation of this site provides insights into the development of shipbo

Societal Costs Associated With Pulmonary Arterial Hypertension Subgroups : A Study Utilizing Linked National Registries

Pulmonary arterial hypertension (PAH) is a heterogenic diagnosis including idiopathic and hereditary PAH (IPAH/HPAH) and groups associated to connective tissue disease (APAH-CTD) and congenital heart disease (APAH-CHD). Pre- and post-diagnosis societal costs in PAH subgroups are not well known. By linking Swedish national databases, societal costs in a national PAH cohort 5 years before and 5 year

Optimization of water intake systems : Based on water-carbon relationships and sustainable development goals

Achieving sustainable development goals requires strategically balancing the trade-off between water resource utilization and carbon emissions. It is of particular importance to systematically study the relationships between water conservation and emission reduction (water-carbon relationship) in a water intake system, and to optimize the water intake structure accordingly. This study proposes a m