This book, which presents a cognitive-semiotic theory of cultural evolution, including that taking place in historical time, analyses various cognitive-semiotic artefacts and abilities. It claims that what makes human beings human is fundamentally the semiotic and cultural skills by means of which they endow their Lifeworld with meaning. The properties that have made human beings special among ani

Since the seriousness and urgency of climate change has surfaced during the last decade, researchers, experts, and even the pope have argued that dealing with it is a moral issue. However, emissions keep rising and it seems as if few people in the north are ready and willing to make any substantial lifestyle changes to minimize the potentially catastrophic consequences, mainly to the south. Intern

The publication of 'A darker side of hypermobility' (Cohen and Gössling, 2015), which reviewed the personal and social consequences of frequent travel, led to considerable media coverage and sparking of the public imagination, particularly with regards to the impacts of business travel. It featured in more than 85 news outlets across 17 countries, engendering over 150,000 social media shares and 4

Guayusa (Ilex guayusa) is a native tree of the western Amazon region grown by indigenou farmers in traditional agroforestry systems. Its leaves are used as a drink similar to tea, which is now commercialized and marketed outside of the Amazon. To assess the impacts from theearly stages of commercial guayusa production, we conducted interviews in four commercial guayusa-producing communities with i

Deterministic lateral displacement (DLD) is a promising method for particle separation in the micrometer range, the proof of principle of which has been demonstrated to be successful in fields such as biomedicine and physics [1]. However, the enhanced particle dispersion (Figure 1 & 2) arising when separating very small particles (such as viruses and proteins) constitutes the main functional b

Context: Miniaturized instruments for percutaneous nephrolithotomy (PNL), utilizing tracts sized ≤22 Fr, have been developed in an effort to reduce the morbidity and increase the efficiency of stone removal compared with standard PNL (>22 Fr). Objective: We systematically reviewed all available evidence on the efficacy and safety of miniaturized PNL for removing renal calculi. Evidence acquisition

We make Deterministic Lateral Displacement (DLD) flexible by combining it with AC electrokinetics.

The Star-C is a new multilevel converter topology that is characterized by presenting a close to perfect sinusoidal output voltage. Its main purpose is to reduce the electromagnetic emissions that can interfere with other equipment placed nearby and to provide a high output power quality without the need of external filters. At the same time, the Star-C requires a significantly lower amount of com

Using Deterministic Lateral Displacement (DLD), we are able to separate bacteria by their size and their chain length. This separation enables the study of these properties as factors of virulence.

We have experimentally studied the conditions for acoustic particle focusing inside aqueous droplets in two-phase-systems, and confirmed our findings by theoretical analysis. The results show that the acoustic properties of the two fluids have to be matched to achieve strong acoustic resonance and focusing in the system.

During the past decade there has been a resurgence of interest in the concept of recognition in international theory. Once the narrow concern of social theorists, the concept of recognition is nowadays invoked in at least three different senses in order to explain three different things. First, it is commonly used to explain how states and their identities are shaped by interaction, and how the mo

The placenta and tumors share important characteristics, including a requirement to establish effective angiogenesis. In the case of the placenta, optimal angiogenesis is required to sustain the blood flow required to maintain a successful pregnancy, whereas in tumors establishing new blood supplies is considered a key step in supporting metastases. Therefore the development of novel angiogenesis

A combination of mesoscale hydrodynamic simulations and microfluidic experiments are used to explore the use of cells' mechanical and dynamical properties as biomarkers for separation. Dynamic behaviour of red blood cells (RBCs) within deterministic lateral displacement (DLD) devices is investigated within various array geometries and for different viscosity contrasts between the intra- and extra-

We derive an expression for the acoustic force density acting on an inhomogeneous fluid with a continuous spatial variation in density and compressibility. A key prediction of our theory, validated by confocal imaging in an acoustofluidic microchip, is that inhomogeneous fluid configurations can be stabilized in the presence of destabilizing forces due to gravity or acoustic streaming flows.

Objective: This study assessed the applicability and outcomes of the closure of unused cuffs in branched endovascular aneurysm repair (b-EVAR) of thoracoabdominal aortic aneurysm. Methods: We reviewed b-EVAR procedures at a tertiary referral center to identify patients who underwent incomplete branching and needed closure of the unused branch cuffs. An electronic database and intraoperative and fo