Background:Cancer rehabilitation is central for helping patients and relatives create a functional everyday life based on the changes in life conditions. The needs are highly individual and include physical, mental, and social challenges. Cancer rehabilitation programs offer coping strategies, including guidelines on how to handle emotions.Objective:This paper presents a participatory design activ

PAH och CTEPH är sällsynta sjukdomar, präglade av andfåddhet, vilket ska utredas tidigt intill klar diagnos föreligger.Omhändertagande vid PAH och CTEPH kräver en multidisciplinär mottagning med specialistutbildade läkare samt kontaktsjuksköterskor.Samarbete mellan SveFPH och patientföreningen PAH Sverige har skapat en nationell samsyn kring PAH- och CTEPH-specialistcentrum och -mottagningar vid lThe PAH and CTEPH care in Sweden is since 2007 structured in collaboration with the Swedish Society of Pulmonary Hypertension (SveFPH) and centralized to pulmonary hypertension (PH) centers at the university hospitals. At biannual SveFPH meetings, ideas are exchanged to spread new knowledge on diagnostics and treatment in Sweden. The PAH-CTEPH centers are to be further stimulated to provide indivi

Hudlymfom är en heterogen grupp av sjukdomar där lymfomcellerna primärt uppträder i huden. T-cellslymfom utgör 70–80 procent och B-cellslymfom 20–30 procent av de primära kutana lymfomen. Mycosis fungoides är det vanligaste hudlymfomet.Den kliniska bilden vid mycosis fungoides kan vara svårtolkad och kan likna vanliga hudsjukdomar som psoriasis och eksem. De histomorfologiska förändringarna vid tiPrimary cutaneous lymphoma is a heterogeneous group of diseases where the malignant lymphocytes are primarily present in the skin at the time of diagnosis. The most common type of primary cutaneous lymphoma is mycosis fungoides. Early stages of mycosis fungoides present with flat or slightly elevated red skin lesions and can resemble eczema or psoriasis. In advanced stages erythrodermia or skin tu

The concentrations of gamma-trace and beta2-microglobulin in cerebrospinal fluid (CSF) and plasma were determined in 64 individuals of various ages without signs of organic disorder in the central nervous system (CNS). A strong connection was found between the CSF level of gamma-trace and the age of the individual, with the CSF level of newborns being 3--4 times that of adults. A similar, but less

The alkaline extract of group A streptococci type 4 was separated by electrophoresis and diffused against 27 normal human sera. One of the precipitates appeared with 85% of the sear. Addition of purified IgA myeloma protein or sera containing IgA M-components to the extract changed the electrophoretic mobility of the precipitate anodically. Purified IgG Fc-fragments or sera containing IgG M-compon

A low molecular weight glycoprotein which completely inhibited trypsin at a 1 : 1 molar ratio was isolated from human urine. It was generated from a precursor molecule which in turn derived from plasma inter-alpha-trypsin inhibitor. It had one polypeptide chain with a molecular weight of about 20 000 and a high content of half-cystine residues. Its amino-terminal amino-acid sequence was Val-Thr-Gl

Various procedures to improve the sensitivity and precision of antigen quantitation by immunocapillarymigration are investigated. The best results are obtained when using porous strips of cellulose acetate with covalently attached antibodies and when enzyme-labeled antibodies are used to expose the antigen-covered areas of the strips. Such a system has a sensitivity of 0.15 mg/liter and a precisio

A simple modification of Greiner electronics selective analyser G300 allowing direct transference of serum samples to the process tubes is described. The modified instrument permitted use of pediatric and capillary blood samples. Eight different capillary analyses were tested on the modified instrument and the results agreed with those obtained by the ordinary analytical macroprocedures of the ins

An IgG Fc-binding protein was isolated from alkaline extracts of group A streptococci type 15 by ion-exchange chromatography and immunosorption on an IgG column. Ample use of protease inhibitors was necessary to achieve successful isolation. 600 micrograms protein was obtained from 60 g bacteria (wet weight). The protein appeared homogeneous on agarose gel and sodium dodecyl sulfate polyacrylamide

Production of red blood cells relies on proper mitochondrial function, both for their increased energy demands during differentiation and for proper heme and iron homeostasis. Mutations in genes regulating mitochondrial function have been reported in patients with anemia, yet their pathophysiological role often remains unclear. PGC1β is a critical coactivator of mitochondrial biogenesis, with incr

Våra röda blodkroppar lever i genomsnitt 120 dagar och bryts därefter ner avmakrofagerna, immunsystemets medfödda städare av både främmande och egnaceller. De röda blodkropparnas uppgift är att transportera syre från lungorna tillkroppens olika vävnader och föra tillbaka koldioxid. Men vad händer om de rödablodkropparna bryts ner ovanligt snabbt eller helt enkelt inte produceras i tillräckligtsnabRed blood cells are are plentiful, flexible and essential. They are the most abundant cell in our body and their mainobject is to carry oxygen, which is essential for cellular respiration. The formation of red blood cells is callederythropoiesis. Erythropoiesis is intimately coupled to cell division and mitochondrial function. Aberrations in thesetwo processes are often associated with red blood c

We propose and experimentally demonstrate a self-calibrating detector of Cooper pair depairing in a superconductor based on a mesoscopic superconducting island coupled to normal metal leads. On average, exactly one electron passes through the device per broken Cooper pair, independent of the absorber volume, device, or material parameters. The device operation is explained by a simple analytical m

Pancreatic cancer, despite being the most dreadful among gastrointestinal cancers, is poorly diagnosed, and further, the situation has been aggravated owing to acquired drug resistance against the single known drug therapy. While previous studies have highlighted the growth inhibitory effects of older generation fluoroquinolones, the current study aims to evaluate the growth inhibitory effects of