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Radiotherapy induces an immediate inflammatory reaction in malignant glioma : a clinical microdialysis study

The knowledge of response to radiation in the immuno-microenvironment of high grade gliomas is sparse. In vitro results have indicated an inflammatory response of myeloid cells after irradiation. Therefore, microdialysis was used to verify whether this is operative in tumor tissue and brain adjacent to tumor (BAT) after clinical radiotherapy of patients with high grade glioma. Stereotactic biopsie

Common cancers share familial susceptibility : Implications for cancer genetics and counselling

Background It has been proposed that cancer is more common in some families than in others, but the hypothesis lacks population level support. We use a novel approach by studying any cancers in large threegeneration families and thus are able to find risks even though penetrance is low. Methods Individuals in the nation-wide Swedish Family- Cancer Database were organised in three generations and t

Outcome of the Swedish Nationwide abdominal aortic aneurysm screening program

Background: A general abdominal aortic aneurysm (AAA) screening program, targeting 65-year-old men, has gradually been introduced in Sweden since 2006 and reached nationwide coverage in 2015. The aim of this study was to determine the outcome of this program. Methods: Data on the number of invited and examined men, screening-detected AAAs, AAAs operated on, and surgical outcome were retrieved from

Pain Sensitivity and its Relation to Spreading on the body, Intensity, Frequency, and Duration of Pain : A Cross-sectional Population-based Study (SwePain)

OBJECTIVES:: Individuals with chronic pain often report increased pain sensitivity compared to pain free individuals, so it is crucial to determine if and how different pain characteristics influence or interact with pain sensitivity. An alternative to experimental pain sensitivity testing is the self-reported pain sensitivity questionnaire (PSQ), that captures pain sensitivity in various body are

Structural pathology is not related to patientreported pain and function in patients undergoing meniscal surgery

Background The relationship between meniscal tears and other joint pathologies with patient-reported symptoms is not clear. We investigated associations between structural knee pathologies identified at surgery with preoperative knee pain and function in patients undergoing arthroscopic meniscal surgery. Methods This study included 443 patients from the Knee Arthroscopy Cohort Southern Denmark (KA

Nätverk för upptäcksresande studenter tioårsjubilerar

Varje år åker 500 studenter från Lunds Tekniska Högskola och andra europeiska lärosäten över Atlanten för att plugga i Latinamerika och Karibien. Lika många åker åt andra hållet. Utbytet sker inom ramen för nätverket Magalhães – där LTH:s vicerektor Per Warfvinge är ordförande.

Nanoteknik ger snabbare 5G-telefoni

Bättre upplösning på radarbilder och snabbare dataöverföringshastigheter inom 5G-telefoni. Det är några av resultaten som ett nytt forskningsprojekt ska åstadkomma. Projektet går under namnet INSIGHT, är finansierat av EU:s Horizon 2020 och koordineras av Lars-Erik Wernersson, professor i nanoelektronik vid Lunds Tekniska Högskola.

N-terminal prosomatostatin as a risk marker for cardiovascular disease and diabetes in a general population

Context: Somatostatin inhibits a range of hormones, including GH, insulin, and glucagon, but little is known about its role in the development of cardiometabolic disease. Objective: The objective of the study was to investigate whether fasting plasma concentration of N-terminal prosomatostatin (NT-proSST) is associated with the development of diabetes, coronary artery disease (CAD), and mortality.

The association between sleep duration, insulin sensitivity, and β-cell function : The EGIR-RISC study

Context: In the past decade, over 3 dozen studies reported a relationship between self-reported short sleep and disturbed glucose metabolism. A study with insulin sensitivity assessed according to the gold standard hyperinsulinemic-euglycemic clamp is, however, still missing. Objective: To evaluate the cross-sectional association of sleep duration with insulin sensitivity and β-cell function in th

Proposed ICDRG Classification of the Clinical Presentation of Contact Allergy

The International Contact Dermatitis Research Group proposes a classification for the clinical presentation of contact allergy. The classification is based primarily on the mode of clinical presentation. The categories are direct exposure/contact dermatitis, mimicking or exacerbation of preexisting eczema, multifactorial dermatitis including allergic contact dermatitis, by proxy, mimicking angioed

Vernacular architecture Reflections : Challenges and Future

Interest in vernacular structures has grown steadily over the past two decades. Vernacular structures around the world are the amalgamation of accumulated cultural, social and religious beliefs as well as practices. The valuable heritage embodied in the vernacular structures has served as sources of inspiration for centuries not only for architects, but also for a diverse, multi-disciplinary commu

Minus carbon and plus energy refugee shelter

This study discusses a proposal for a 37 m² refugeeearth shelter that could be built with the help of sevenpeople in 11 working days. The study is an experimental, participatory, living lab methodology for creating an eco-cycle shelter. The building’s skeleton is made from a minus carbon earth mix and is equipped with renewables that produce more energy than what the building consumes. No waste is

The circulatory system and a new cell type of the cephalocarid crustacean Hutchinsoniella macracantha

The circulatory system of Hutchinsoniella macracantha consists of a tubular heart in thoracic segments 1–6, a dorsoposterior channel, and body fluid (“haemocoelic”) sinuses. The heart, which is possibly closed anteriorly, has three paired ostia dorsolaterally in thoracic segments 2–4. The heart wall is formed by two cellular layers: an inner myocardium and an outer epicardium. The myofibrils are o

Baring it all- undressing Cambrian ´Orsten´phosphatocopine arthropods using synchrotron X-ray tomographic microscopy

Synchrotron radiation X-ray tomographic microscopy (SRXTM) was used to virtually dissect and peel the shields off of the microscopic, bivalved phosphatocopine crustaceans in the Cambrian ‘Orsten’ type of preservation of Sweden. Doing so opened up for an array of concealed internal structures to be observed in a fully enclosed specimen of Hesslandona ventrospinata and a semi-enclosed specimen of He