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The role of the clinical departments for understanding patient heterogeneity in one-year mortality after a diagnosis of heart failure : A multilevel analysis of individual heterogeneity for profiling provider outcomes

PURPOSE: To evaluate the general contextual effect (GCE) of the hospital department on one-year mortality in Swedish and Danish patients with heart failure (HF) by applying a multilevel analysis of individual heterogeneity.METHODS: Using the Swedish patient register, we obtained data on 36,943 patients who were 45-80 years old and admitted for HF to the hospital between 2007 and 2009. From the Dan

Constraining a terrestrial biosphere model with remotely sensed atmospheric carbon dioxide

We present two novel earth observation products derived from the BESD and EMMA XCO2 products which were respectively retrieved from SCIAMACHY and GOSAT observations within the GreenHouse Gas project of ESA's Climate Change Initiative (GHG-CCI). These products are inferred by a Carbon Cycle Data Assimilation System (CCDAS) and consist of net and gross biosphere-atmosphere fluxes of carbon dioxide o

Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers

IMPORTANCE The clinical management of BRCA1 and BRCA2 mutation carriers requires accurate, prospective cancer risk estimates. OBJECTIVES To estimate age-specific risks of breast, ovarian, and contralateral breast cancer for mutation carriers and to evaluate risk modification by family cancer history and mutation location. DESIGN, SETTING, AND PARTICIPANTS Prospective cohort study of 6036 BRCA1 and

Lower age increases the risk of revision for stemmed and resurfacing shoulder hemi arthroplasty : A study from the Swedish shoulder arthroplasty register

Background and purpose — The number of patients where shoulder hemiarthroplasty (SHA) is an option is still substantial. Descriptive analyses performed by the Swedish Shoulder Arthroplasty Registry (SSAR) showed that while patients receiving SHA designs, i.e. resurfacing hemi (RH) and stemmed hemi (SH), reported similar shoulder functionality and quality of life, the revision rate for RH (12%) was

The impact of ethnic communities on immigrant entrepreneurship : evidence from Sweden

This paper seeks to provide novel insights into the effects of ethnic communities on immigrants’ entrepreneurial activities. We investigate to what extent the decision of an employed immigrant to become an entrepreneur is associated with his or her embeddedness in ethnic networks in the host region. We capture such embeddedness through various mechanisms. Using longitudinal-registered data from Sw

Anthropometric and metabolic improvements in human type 2 diabetes after introduction of an Okinawan-based Nordic diet are not associated with changes in microbial diversity or SCFA concentrations

The Okinawan-based Nordic (O-BN) diet improves anthropometry and metabolism in type 2 diabetes mellitus (T2DM) patients. The aim of this study was to study mechanisms behind improvements by examining Enterobacteriaceae abundance, microbial diversity, and concentrations of short-chain fatty acids (SCFAs). A secondary aim was exploring if metformin treatment affects microbiota or SCFAs. Thirty T2DM

Gotlands – Nationen som försvann

Kort historik om den på 1700-talet verksamma Gotlands nation vid Lunds universitet samt uppgifter om några av dess medlemmars senare öden.

Insight into the reaction mechanism of lipoyl synthase : a QM/MM study

Lipoyl synthase (LipA) catalyses the final step of the biosynthesis of the lipoyl cofactor by insertion of two sulfur atoms at the C6 and C8 atoms of the protein-bound octanoyl substrate. In this reaction, two [4Fe4S] clusters and two molecules of S-adenosyl-l-methionine are used. One of the two FeS clusters is responsible for the generation of a powerful oxidant, the 5′-deoxyadenosyl radical (5′-

On the Characterization of Triebel–Lizorkin Type Spaces of Analytic Functions

We consider different characterizations of Triebel–Lizorkin type spaces of analytic functions on the unit disc. Even though our results appear in the folklore, detailed descriptions are hard to find, and in fact we are unable to discuss the full range of parameters. Without additional effort we work with vector-valued analytic functions, and also consider a generalized scale of function spaces, in

Development and validation of a new assessment tool for suturing skills in medical students

Background: In recent years, emphasis has been put on that medical student should demonstrate pre-practice/pre-registration core procedural skills to ensure patient safety. Nonetheless, the formal teaching and training of basic suturing skills to medical students have received relatively little attention and there is no standard for what should be tested and how. The aim of this study was to devel

Histone profiling reveals the H1.3 histone variant as a prognostic biomarker for pancreatic ductal adenocarcinoma

Background: Epigenetic alterations have been recognized as important contributors to the pathogenesis of PDAC. However, the role of histone variants in pancreatic tumor progression is still not completely understood. The aim of this study was to explore the expression and prognostic significance of histone protein variants in PDAC patients. Methods: Liquid chromatography-tandem mass spectrometry (

"From resistance to challenge" : Child health service nurses experiences of how a course in group leadership affected their management of parental groups

Background: All parents in Sweden are invited to child health service (CHS) parental groups, however only 49% of the families participate. The way the parental groups are managed has been shown to be of importance for how parents experience the support and CHS nurses describe feeling insecure when running the groups. Lack of facilitation, structure and leadership might jeopardise the potential ben

Timing of oral anticoagulant therapy in acute ischemic stroke with atrial fibrillation : Study protocol for a registry-based randomised controlled trial

Background: Oral anticoagulation therapy is recommended for the prevention of recurrent ischemic stroke in patients with atrial fibrillation (AF). Current guidelines do not provide evidence-based recommendations on optimal time-point to start anticoagulation therapy after an acute ischemic stroke. Non-vitamin K antagonist oral anticoagulants (NOACs) may offer advantages compared to warfarin becaus

Arterial stiffness and incidence of diabetes : A population-based cohort study

Objective: Diabetes is known to be associated with increased arterial stiffness. However, the temporal association between increased carotid-femoral pulse wave velocity (c-f PWV) and diabetes is unclear. The aim of this study is to explore the relationship between arterial stiffness, as determined by c-f PWV, and incidence of diabetes. Research Design and Methods: The study population included par

Utvärdering av utvecklingsstatus för fuktanalysmetoder : Utvärdering och uppföljning av projektet CONMOD del II

Rapporten avser följa upp och utvärdera de resultat som kom från projektet CONMOD rörande fuktanalyser. I de sju rapporterna som har utgjort underlag för denna undersökning har står det generellt sett väldigt lite om fukt med två undantag. De två rapporter där det står mest om fukt och fuktmodellering, är dels i bilaga A5.4, i rapporten ”Barsebäck NPP- Material testing project”, Materialanalyser a

Determinants of variable resource use for multidisciplinary team meetings in cancer care

Background: Multidisciplinary team meetings (MDTMs) have developed into standard of care to provide expert opinion and to grant evidence-based recommendations on diagnostics and treatment of cancer. Though MDTMs are associated with a range of benefits, a growing number of cases, complex case discussion and an increasing number of participants raise questions on cost versus benefit. We aimed to det

Verifiering av struktur och fuktmekaniska beräkningsverktyg : Tillämpning på reaktorinneslutningars betongkonstruktioner, Vercors Fas 1

Électricité de France har utanför Paris byggt en 1/3 skalmodell av en reaktorinneslutning motsvarande en fransk fullskalereaktor modell P4. Anläggningen möjliggör studier av hur åldringsprocesser påverkar förspända reaktorinneslutningar. Syftet är att efter de 7 år som ett övergripande forskningsprojektet vid på anläggningen pågår, uppnå påverkan motsvarande den åldring som en fullskalereaktor har

High visual acuity revealed in dogs

Humans have selectively bred and used dogs over a period of thousands of years, and more recently the dog has become an important model animal for studies in ethology, cognition and genetics. These broad interests warrant careful descriptions of the senses of dogs. Still there is little known about dog vision, especially what dogs can discriminate in different light conditions. We trained and test

Combining shock barometry with numerical modeling : Insights into complex crater formation—The example of the Siljan impact structure (Sweden)

Siljan, central Sweden, is the largest known impact structure in Europe. It was formed at about 380 Ma, in the late Devonian period. The structure has been heavily eroded to a level originally located underneath the crater floor, and to date, important questions about the original size and morphology of Siljan remain unanswered. Here we present the results of a shock barometry study of quartz-bear