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Protein kinase C (PKC) is a family of serine/threonine kinases which are subgrouped into classical (a, bI, bII, g), novel (d, e, h, q) and atypical (z, i/l) isoforms. It has been shown that PKCe induces neurite outgrowth in neuroblastoma cells and the effect is mediated via the regulatory domain. One aim of this study was to identify the structures in PKCe that mediate neurite outgrowth. This stu
A reaction-diffusion model was used to simulate a co-immobilized system utilizing the numerical method of orthogonal collocation. The production of ethanol from deproteinized whey using beta-galactosidase co-immobilized with Saccharomyces cerevisiae in calcium alginate gel beads was chosen as a model system. Calculated concentrations of lactose, glucose, galactose and ethanol were compared with ex
This paper deals with line-drawings, obtained from images of piecewise planar objects after edge detection. Such images are used, e.g., for navigation and recognition. In order to be a possible image of a three dimensional piecewise planar object, it has to obey some projective conditions. Criteria for a line-drawing to be correct is given in this paper, along with methods to find possible interpr
The aerobic degradation of phenanthrene by a Pseudomonas migulae strain under classical mechanical aeration and under photosynthetic oxygenation (using a Chlorella sorokiniana strain) in a two-phase partitioning bioreactor (TPPB) constructed with silicone oil as organic phase was investigated. When traditional mechanical aeration was used, an increase in the aeration and/or in the agitation rate e
In the radioimmunotherapy of malignancies the uptake of monoclonal antibodies (MoAb) is commonly low in tumors compared with normal tissue. Several methods have been suggested to increase the tumor-to-normal tissue (T/N) ratio. In this study we have investigated the biodistribution of different amounts of 125I-L6-biotin MoAb in combination with a preload of unlabeled L6 MoAb. Nude rats were inject
The alkali metal emission from materials collected in a PFB biomass gasification pilot plant has been characterized. Samples of SiC filter ash and fluidized bed particles from different operating conditions were subjected to a constant heating rate up to 1000 degrees C in a nitrogen atmosphere, and the alkali metal emission was monitored continuously by a surface ionization technique. For all samp
The utility of the PCR-based AFLP technique (polymerase chain reactions amplified fragment length polymorphisms) was explored in elucidating details of polyploid evolution in the Eurasian orchid genus Dactylorhiza. We emphasized Swedish taxa but also included some material from the British Isles and elsewhere in Europe. Three different sets of primers, amplifying different subsets of restriction f
Protein G-related alpha(2)-macroglobulin-binding (GRAB) protein is a cell wall-attached determinant of group A streptococcus (GAS) that interacts with the human protease inhibitor a 2-macroglobulin (alpha(2)-M). Of 86 clinical isolates tested, 23% could bind a alpha(2)-M. However, all strains tested contained the grab gene. High levels of anti-GRAB antibodies were found in the serum of convalescen
Introduction: Risedronate, a bisphosphonate for treatment and prevention of osteoporosis, has been shown in several clinical trials to reduce the risk of fractures in postmenopausal women with osteoporosis. The cost-effectiveness of risedronate treatment has previously been evaluated within different country settings using different model and analysis approaches. The objective of this study was to
Polychlorinated biphenyls (PCBs) and organic pesticides (i.e., DDTs) were measured in long finned eels (Anguilla dieffenbachii) in 17 streams on the west coast of South Island, New Zealand. Very low levels of PCBs and low levels of ppDDE were found. The concentrations of PCBs and ppDDE were not correlated within sites indicating that different processes determined the levels of the two pollutants
Pre-treatment of sludge before anaerobic digestion can increase methane production and degradation of organic matter. There are various pre-treatment methods for this purpose. Anaerobic digestion tests were performed for comparison of three pre-treatment methods (hygienisation, ultrasonic treatment and enzyme dosing) used separately or in combination on biosludge and mixed sludge. COD solubilisati
We compare the generation and decay dynamics of charges and excitons in a model polymer semiconductor (MEH-PPV) in solution and drop-cast thin films, by recording the sub-ps transient complex conductivity using THz time-domain spectroscopy. The results show that the quantum efficiency of charge generation is two orders of magnitude smaller in solution (~10–5) than in the solid film (~10–3). The pr
Excited states in the N=Z+1 nucleus Kr-73 have been investigated using the Ca-40(Ar-36,2pn) and Ca-40(Ca-40,alpha2pn) reactions at 145 and 160 MeV, respectively. gamma rays were detected using the Gammasphere array and events were recorded in coincidence with charged-particle and neutron detectors. The three previously observed bands were extended to high spin, and a new unfavored positive-parity
Popular Abstract in Swedish Kartering av primärproduktion i Västrafrikanska Sahel genom användning av satellitdata. I avhandlingen har utvecklats en Light Use Efficency (LUE) modell som medger kartering av bruttoprimärproduktionen (GPP) exemplifierad i ett område i Västafrikanska Sahel. Modellen utnyttjar satellitbaserad månatlig Normalised Difference Vegetation Index (NDVI) tillsammans med andraA light Use Efficiency (LUE) model is developed that allows the mapping of total growing season Gross Primary Production (GPP) for the West African Sahel, using the Normalized Difference Vegetation Index (NDVI) together with other data. Image quality may be poor in monthly NDVI maximum value composites as shown by an improved geostatistical noise estimation technique. Quality may be improved by ot
Dissociation of 6He on a lead target has been studied at 240 MeV/u. The four-momenta of the two neutrons in coincidence with greek small letter alpha-particles have been measured and used to reconstruct the three-body energy and angular correlations in the final state. For the first time, three-body correlations were included in the analysis of the 6He dissociation data, and compared with calculat
Regulation of the telomerase catalytic subunit, hTERT, is a complex process accomplished on many levels. Transcription of the hTERT gene has been widely studied but less is known about the implication of genetic variations. Recently, a functional T to C transition polymorphisin was indicated 1327 bp upstream the hTERT transcription starting site. The C-1327/C genotype was associated with shorter t
