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Temperature effects on incidence of surgery for acute type A aortic dissection in the Nordics

We aimed to investigate a hypothesised association between daily mean temperature and the risk of surgery for acute type A aortic dissection (ATAAD). For the period of 1 January 2005 until 31 December 2019, we collected daily data on mean temperatures and date of 2995 operations for ATAAD at 10 Nordic cities included in the Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD) collaborati

Optical cavity-mediated exciton dynamics in photosynthetic light harvesting 2 complexes

Strong light-matter interaction leads to the formation of hybrid polariton states and alters the photophysical dynamics of organic materials and biological systems without modifying their chemical structure. Here, we experimentally investigated a well-known photosynthetic protein, light harvesting 2 complexes (LH2) from purple bacteria under strong coupling with the light mode of a Fabry-Perot opt

The Harald Breivik lecture 2022. Pathophysiology in persistent severe pain after groin hernia repair

The transition from a healthy to a persistent severe pain state following otherwise successful elective surgery is a feared complication. Groin hernia repair, previously considered minor surgery, is a standard surgical procedure annually performed on 2,000 individuals per one million residents. A trajectory into persistent severe pain is, unfortunately, seen in 2-4%, severely impeding physical and

Progression models for repeated measures : Estimating novel treatment effects in progressive diseases

Mixed models for repeated measures (MMRMs) are ubiquitous when analyzing outcomes of clinical trials. However, the linearity of the fixed-effect structure in these models largely restrict their use to estimating treatment effects that are defined as linear combinations of effects on the outcome scale. In some situations, alternative quantifications of treatment effects may be more appropriate. In

Synthesis and experimental study of improved double perovskite-type PrBaCo2O5+δ materials to produce oxygen-enriched CO2 for oxyfuel combustion application

Perovskite oxides are promising oxygen carrier materials to produce O2/CO2 gas for oxyfuel combustion application. In this study, PrBaCo2O5+δ double perovskite oxide was prepared by the EDTA sol-gel method and first applied as oxygen carrier for oxygen production. The oxygen adsorption/desorption performance of PrBaCo2O5+δ perovskite was carrried out in a fixed-bed set-up. The operating factors of

The Pitfalls of Enhanced Cooperation : The case of the European public prosecutor

There has been a public debate among academics and politicians of whether Hungary should be required to join the European Public Prosecutor’s Office as a condition to receive EU funds according to the different milestones. As the EPPO is tasked with investigating fraud and mismanagement of EU funds, it is well-placed to address the allegations of serious corruption that the Hungarian Government is

Backyard buzz : human population density modifies the value of vegetation cover for insect pollinators in a subtropical city

Urbanisation drives overall declines in insect pollinators. Although urban green spaces can provide suitable habitat for pollinators much remains to be learned about how urban landscapes either promote or negatively impact pollinators. We investigated how backyard design, local (100 m) and landscape (500 m) scale vegetation cover and human population density were associated with non-eusocial nativ

Observation of the Multilayer Growth Mode in Ternary InGaAs Nanowires

Au-seeded semiconductor nanowires have classically been considered to only grow in a layer-by-layer growth mode, where individual layers nucleate and grow one at a time with an incubation step in between. Recent in situ investigations have shown that there are circumstances where binary semiconductor nanowires grow in a multilayer fashion, creating a stack of incomplete layers at the interface bet

Muscle mass and quality as predictors for complications, recurrence and length of hospital stay in acute uncomplicated diverticulitis: a retrospective cohort study

ObjectivesThe aim of this study was to investigate the potential correlation between muscle mass/muscle quality and risk of complications or recurrence in patients presenting with acute uncomplicated diverticulitis. It was also to study if low muscle mass/quality correlated to prolonged hospital stay.Materials and methodsThe study population comprised 501 patients admitted to Helsingborg Hospital

Clinical, economic, and health-related quality of life burden associated with von Willebrand disease in adults and children : Systematic and targeted literature reviews

Introduction: Debilitating clinical complications in von Willebrand disease (VWD) can affect health-related quality of life (HRQoL), increase healthcare costs and cause long-lasting consequences. However, the magnitude of these burdens needs to be more fully explored. Aim: To estimate the prevalence and burden of clinical complications, the impact on HRQoL and the economic burden associated with V

Mapping exercise and status update of eight established registries within the TREatment of ATopic eczema Registry Taskforce

Background: The TREatment of ATopic eczema (TREAT) Registry Taskforce is a collaborative international network of registries collecting data of atopic eczema (AE) patients receiving systemic and phototherapy with the common goal to provide long-term real-world data on the effectiveness, safety and cost-effectiveness of therapies. A core dataset, consisting of domains and domain items with correspo

Genomic trajectories of a near-extinction event in the Chatham Island black robin

Background: Understanding the micro-­evolutionary response of populations to demographic declines is a major goal in evolutionary and conservation biology. In small populations, genetic drift can lead to an accumulation of deleterious mutations, which will increase the risk of extinction. However, demographic recovery can still occur after extreme declines, suggesting that natural selection may pu

Infarct quantification with cardiovascular magnetic resonance using "standard deviation from remote" is unreliable : validation in multi-centre multi-vendor data

Background: The objective of the study was to investigate variability and agreement of the commonly used image processing method “n-SD from remote” and in particular for quantifying myocardial infarction by late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR). LGE-CMR in tandem with the analysis method “n-SD from remote” represents the current reference standard for infarct qu

Surface guided 3DCRT in deep-inspiration breath-hold for left sided breast cancer radiotherapy : implementation and first clinical experience in Iran

Background: The aim of the study is to evaluate the overall accuracy of the surface-guided radiotherapy (SGRT) workflow through a comprehensive commissioning and quality assurance procedures and assess the potential benefits of deep-inspiration breath-hold (DIBH) radiotherapy as a cardiac and lung dose reduction approach for left-sided breast cancer irradiation. Materials and methods: Accuracy and

The relationship between retail stores and public safety in disadvantaged areas in Sweden

This paper contributes to previous research on retail safety by extending the concept of safety beyond the retail store. To this end, the aim of the research is to examine the mutual relationship between retail stores and public safety in disadvantaged urban environments. The goal is to demonstrate the potential of physical retail establishments in urban environments for creating resilient and soc

Syncope in hypertrophic cardiomyopathy (part II) : An expert consensus statement on the diagnosis and management

Syncopal events in patients with hypertrophic cardiomyopathy (HCM) are of concern as they are a vital consideration in algorithms for risk stratification for sudden cardiac death (SCD) and ICD implantation. However, the cause of syncope is often under-investigated and/or unexplained. Current syncope guidelines do not provide a detailed definition of unexplained syncope. To address this important g