Starting from the assumption that grammaticalization is rooted in situated language use, the present study tests the connection between functional reanalysis and formal reduction with a synchronic approach. It investigates a case of potential (but not actuated) grammaticalization in Present-Day English, the use of epistemic phrases of the type it could/might be (that), which can serve an adverbial

Objective: Changes observed during adult GH deficiency (GHD) are most often reversed with the administration of recombinant human GH (rhGH). To avoid daily injections, a long-acting GH molecule has been obtained by covalent binding of polyethylene glycol (PEG) with rhGH (PEG-GH), allowing weekly s.c. injections. This study was designed to assess its efficacy and safety, in adult GHD subjects.Desig

Objective: The effects of GH replacement on glucose metabolism in GH-deficient (GHD) adults in clinical practice are not well defined. Therefore, we assessed GH treatment effects on fasting plasma glucose (FPG) and haemoglobin A1c (A1c) concentrations in GHD adults in a clinical setting.Design: Post-hoc analysis of the observational Hypopituitary Control and Complications Study conducted at 157 US

The exclusive production of pion pairs in the process pp→ ppπ+π- has been measured at s=7TeV with the ATLAS detector at the LHC, using 80μb-1 of low-luminosity data. The pion pairs were detected in the ATLAS central detector while outgoing protons were measured in the forward ATLAS ALFA detector system. This represents the first use of proton tagging to measure an exclusive hadronic final state at

Hålla tarmbakterier i schack hos unga möss Efter födseln exponeras ett spädbarn för den yttre miljön för första gången. Detta innebär exponering för ett stort antal bakterier och virus. Spädbarn är mer benägna att bli infekterade av bakterier och virus än vuxna. Hos vuxna kan antikroppen Immunoglobulin A (IgA) hjälpa till att hålla bakterier och virus i schack genom att omsluta dem och agera som The period after birth, when an infant is initially exposed to vast amounts of environmental and microbial antigens, sets the stage for proper immune system development ensuing lifelong immunity. Simultaneous to this first-time exposure, the nursing mother provides immune protection via antibodies in the breast milk. Secretory Immunoglobulin A, as provided by the mother or produced intrinsically i

We present measurements of the cross section and double-helicity asymmetry ALL of direct-photon production in p→+p→ collisions at s=510 GeV. The measurements have been performed at midrapidity (|η|

The honeybee Apis mellifera, with a brain of only 960,000 neurons and the ability to perform sophisticated cognitive tasks, has become an excellent model in life sciences and in particular in cognitive neurosciences. It has been used in our laboratories to investigate brain and behavioural asymmetries, i.e., the different functional specializations of the right and the left sides of the brain. It

What are we subjected to when presented with stories about art's past in the context of classrooms or collections? In order to prepare students for a profession in the humanities or in the field of artistic production and reception at large, art history courses in higher education are obliged to provide them with an understanding for the collection of texts, debates or works of art that are consid

Archaeological data repositories usually manage excavation data collections as project-level entities with restricted capacities to facilitate search or aggregation of excavation data at the sub-collection level (trenches, finds, season reports or excavation diaries etc.). More granular access to excavation data collections would enable layered querying across their informational content. In the p

Resting-state fMRI has proven to entail subject-specific signatures that can serve as a fingerprint to identify individuals. Conventional methods are based on building a connectivity matrix based on correlation between the average time course of pairs of brain regions. This approach, first, disregards the exquisite spatial detail manifested by fMRI due to working on average regional activities, se

The guiding question of this paper is how (horizontal) connections are established when new items enter the network of constructions. It presents a quantitative, corpus-based study of the development of to-contraction (e.g. want to > wanna) in American English since the 19th century. From a plethora of earlier forms, gonna, wanna and gotta emerge, first as representations of phonetic reduction, bu