Microvascular inflammatory response in the skin
Popular Abstract in Swedish I denna avhandling studeras den akuta inflammatoriska reaktionen i huden. Akut inflammation beskrevs redan under romersk tid av Aulus Cornelius Celsus. Han karakteriserade denna reaktion med rodnad, svullnad, värme och smärta. Fysiologiskt består akut inflammation av vidgning av små blodkärl (vasodilatation) som ger upphov till rodnad samt av läckage av plasmaproteiner This thesis examines the microvascular inflammatory response in the skin. The microvascular response includes vasodilatation and plasma exudation. In the first three studies, the combined response was measured in guinea pig skin with a technique based on detection of radiolabelled protein. Transferrin was labelled in vivo by injection of 113mIn and the conversion electrons detected over the skin u