PURPOSE OF REVIEW: The purpose of this review is to provide a comprehensive evaluation of the most important type 2 diabetes gene to date, transcription factor 7 like-2. RECENT FINDINGS: An important step to find genetic causes of type 2 diabetes in 2006 was the identification of the fact that variants in the gene encoding transcription factor 7 like-2 reproducibly increase susceptibility to type

Bröstcancer är den vanligaste cancerformen hos kvinnor i Sverige. Tio procent av den kvinnliga befolkningen får bröstcancer under sin livstid. En minoritet avlider. Operation är den vanligaste behandlingen som oftast kombineras med strålbehandling. Det är mindre känt att vissa sidoeffekter av behandlingen kan ge bestående fysisk påverkan. Sådana bieffekter är armlymfödem samt nedsatt axelrörlighet

The aim of the thesis is to highlight how children are created as subjects when their behaviour puzzles, worries or challenges staff in preschool, and how scope for, or limitations to, the children's opportunities to be, know or act differently thereby emerge. An additional purpose is to shed light on how suggestions for ways of managing and, in Foucault’s sense, governing the children and their b

In digital control systems, the state is sampled at given sampling instants and the input is kept constant between two consecutive instants. With the optimal sampling problem, we mean the selection of sampling instants and control inputs, such that a given function of the state and input is minimized. In this paper, we formulate the optimal sampling problem and we derive a necessary condition of t

One reason for the relatively small number of real-world applications of simulation in software engineering is the existing lack of guidance in creating and formulating the related models and in the isolated usage of associated techniques. In order to support both strategic and project management in software organizations, a methodology for integrated measurement, modelling and simulation (IMMoS)

InAs is an attractive channel material for III–V nanowire MOSFETs and early prototype high performance nanowire transistors have been demonstrated1. As the gate length is reduced, the nanowire diameter must be scaled quite aggressively in order to suppress short-channel effects2. However, a reduction in transconductance (gm) and drive current (ION) could be expected due to increased surface scatte

Women around 1900, emancipation, professional women.

Object Cerebral ischemia remains the key cause of disability and death in the late phase after subarachnoid hemorrhage (SAH), and its pathogenesis is still poorly understood. The purpose of this study was to examine whether the change in intracranial pressure or the extravasated blood causes the late cerebral ischemia and the upregulation of receptors or the cerebral vasoconstriction observed foll

Kulturkrönika om 2002 års Fantastisk Filmfestival i Lund och de prisvinnande filmerna.