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On-line monitoring of a two-stage anaerobic digestion process using a BOD analyzer

A computer-controlled biochemical oxygen demand (BOD) analyzer has been developed for fast estimation of biochemical oxygen demand (BOD,,) automatically with the purpose of on-line monitoring of a process for conversion of biomass under field conditions. The instrument was tested by on-line monitoring of the connecting stream between two stages of a two-stage anaerobic process in laboratory scale.

Disentangling dysthymia from major depressive disorder in suicide attempters' suicidality, comorbidity and symptomatology.

Dysthymia and major depressive disorder (MDD) are both risk diagnoses for suicidal behaviour. The aim of the present study was to identify clinical differences between these disorders, with a special reference to dysthymia. We studied suicidal behaviour, comorbidity and psychiatric symptoms of inpatient suicide attempters with dysthymia and MDD. We used DSM III-R diagnostics, the Suicide Assessmen

Intrapleural fluid movements described by a porous flow model

We injected technetium-labeled albumin (at a concentration similar to that of the pleural fluid) in the costal region of anesthetized dogs (n = 13) either breathing spontaneously or apneic. The decay rate of labeled activity at the injection site was studied with a gamma camera placed either in the anteroposterior (AP) or laterolateral (LL) projection. In breathing animals (respiratory frequency a

Major role of human KLK14 in seminal clot liquefaction

Liquefaction of human semen involves proteolytic degradation of the seminal coagulum and release of motile spermatozoa. Several members of human kallikrein-related peptidases (KLKs) have been implicated in semen liquefaction, functioning through highly regulated proteolytic cascades. Among these, KLK3 (also known as prostate-specific antigen) is the main executor enzyme responsible for processing

High-resolution diffusion imaging using phase-corrected segmented echo-planar imaging

Diffusion magnetic resonance imaging (MRI) was performed with a high-resolution segmented echo-planar imaging technique, which provided images with substantially less susceptibility artifacts than images obtained with single-shot echo-planar imaging (EPI). Diffusion imaging performed with any multishot pulse sequence is inherently sensitive to motion artifacts and in order to reduce motion artifac

Context dependence of protein secondary structure formation: the three-dimensional structure and stability of a hybrid between chymotrypsin inhibitor 2 and helix E from subtilisin Carlsberg

The loop region of chymotrypsin inhibitor 2 from barley has been employed as a scaffold for testing the intrinsic propensity of a peptide fragment to form a secondary structure. The helix formation of the nine amino acid residue segment Lys-Gln- Ala-Val- Asp- Asn- Ala-Tyr-Ala of helix E from subtilisin Carlsberg has been studied by the construction of a hybrid consisting of chymotrypsin inhibitor

The wide world of wide-area measurement

The interest in phasor measurement technology has reached a peak in recent years, as the need for the best estimate of the power system's state is recognized to be a crucial element in improving its performance and its resilience in the face of catastrophic failures. In most countries installing the phasor measurement units (PMUs) and getting to know the PMU system behavior through continuous obse

Digital elevation data for estimation of potential wetness in ridged fields - Comparison of two different methods

The aim of this study was to develop, adjust and test two different methods for the estimation of drainage area and potential wetness in ridged fields. The methods were applied to a gridded digital elevation model (DEM) of a potato field in central Sweden. Elevation data were registered by a global positioning system (GPS) receiver. A high-precision real time kinematic (RTK) system was used to rec

Small-Angle Neutron Scattering on a Core-Shell Colloidal System: A Contrast Variation Study

Small-angle neutron scattering (SANS) measurements are reported on a sterically stabilized, coreshell colloidal system using contrast variation. Aqueous dispersions of polystyrene particles bearing grafted poly(ethylene glycol) (PEG) have been studied over a large range of particle concentrations and two different solvent conditions for the PEG polymer. SANS data are analyzed quantitatively by mod

An integrated analysis of five double-blind, randomized controlled trials evaluating the safety and efficacy of a hyaluronan product for intra-articular injection in osteoarthritis of the kneel

Objective: Five double-blind, randomized, saline-controlled trials (RCTs) were included in the United States marketing application for an intra-articular hyaluronan (IA-HA) product for the treatment of osteoarthritis (OA) of the knee. We report an integrated analysis of the primary Case Report Form (CRF) data from these trials. Method. Trials were similar in design, patient population and outcome

Changes in European ecosystem productivity and carbon balance driven by regional climate model output

Climate change resulting from the enhanced greenhouse effect together with the direct effect of increased atmospheric CO2 concentrations on vegetation growth are expected to produce changes in the cycling of carbon in terrestrial ecosystems. Impacts will vary across Europe, and regional-scale studies are needed to resolve this variability. In this study, we used the LPJ-GUESS ecosystem model drive

Genetic variants of thiazide-sensitive NaCl-cotransporter in Gitelman's syndrome and primary hypertension

Gitelman's syndrome is an autosomal recessive disorder characterized by electrolyte disturbances and low blood pressure. The disease is caused by homozygous or compound heterozygous inactivating mutations in the thiazide-sensitive NaCl-cotransporter gene leading to reduced renal sodium reabsorption. We report 4 patients with Gitelman's syndrome from southern Sweden, all in whom we identified compo

Actions downstream of cGMP/PKG can reverse PKC-mediated phosphorylation of CPI-17 and Ca2+ sensitization in smooth muscle.

Ca2+ sensitivity of smooth muscle contraction is modulated by several systems converging on myosin light chain phosphatase (MLCP). Rho-Rho kinase is considered to inhibit MLCP via phosphorylation, whereas protein kinase C (PKC) induced sensitization has been shown to be dependent on phosphorylation of the inhibitory protein CPI-17. We have explored the interaction of cGMP-dependent protein kinase

Upconversion luminescence of Eu3+ and Mn2+ in ZnS : Mn2+, Eu3+ codoped nanoparticles

Strong upconversion luminescence of both Mn2+ and Eu3+ is observed in ZnS:Mn2+, Eu3+ codoped nanoparticles. Laser power dependencies and spectroscopic data show that the upconversion emission is due to two-photon excitation of each specific dopant ion. The relative differences in two-photon excitation cross section result in different relative intensities for the Eu3+ and Mn2+ upconversion at diff