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A Time and Place for Agency

Om platser verkligen är av betydelse, vilket ekonomiska geografer anser, då måste de vara som mest betydelsefulla för de människor vars liv utspelar sig på dessa platser, och upplever världen, materiellt kan kulturellt, genom den. När en kris och efterföljande osäkerheter drabbar en plats så påverkar detta främst människorna som kallar denna platsen för sitt hem. Ibland till den grad att en del avIf places indeed matter, as economic geographers believe, then it must matter most to the people who live their everyday lives in these places and experience the world materially and socially through it. When a crisis hits and uncertainty ensues, it affects people who call these places home the most. So much so, that some of them might be willing to stake a claim on its recovery, and development t

The use of collected memories : Challenges in differences

During 2020 archives and museums collected both personal memories and artifacts related to the corona outbreak. The aim was to document the unique situation and to save memories for the future. How can the experiences from this year be used in cooperation between academia and archives and museums?

[P]ers[on]a mis[ce]lanea : Works of Manuel Ponce by Bertrand Chavarría-Aldrete

This release brings together some of Ponce’s finest guitar works, carefully selected and sensitively performed by Bertrand Chavarría-Aldrete. The album opens with a Preludio written not long after Ponce arrived in Paris, characterised by modal and whole tone inflections that lend the piece an impressionistic quality. The release also includes the later set of Seis preludios cortos (‘Six short prel

The effect of tezepelumab on airway hyperresponsiveness to mannitol in asthma (UPSTREAM)

RATIONALE AND OBJECTIVES: Thymic stromal lymphopoietin (TSLP), an epithelial upstream cytokine, initiates production of type-2 (T2) cytokines with eosinophilia and possibly airway hyperresponsiveness (AHR) in asthma.This study aimed to determine whether tezepelumab (a human monoclonal antibody targeting TSLP) decreases AHR and airway inflammation in patients with symptomatic asthma on maintenance

Reinterpretation of excited states in 212Po: Shell-model multiplets rather than α-cluster states

A γ-ray spectroscopic study of 212Po was performed at the Grand Accélérateur National d'Ions Lourds, using the inverse kinematics α-transfer reaction 12C(208Pb,212Po)8Be and the AGATA spectrometer. A careful analysis based on γγ coincidence relations allowed us to establish 14 new excited states in the energy range between 1.9 and 3.3 MeV. None of these states, however, can be considered as candid

First experiments with a water-jet plasma X-ray source driven by the novel high-power-high-repetition rate L1 Allegra laser at ELI Beamlines

ELI Beamlines is a rapidly progressing pillar of the pan-European Extreme Light Infrastructure (ELI) project focusing on the development and deployment of science driven by high-power lasers for user operations. This work reports the results of a commissioning run of a water-jet plasma X-ray source driven by the L1 Allegra laser, outlining the current capabilities and future potential of the syste

Carbon Embedding of Pt Cluster Superlattices Templated by Hexagonal Boron Nitride on Ir(111)

With the goal to delevop the fabrication of a new type of Pt-nanoparticle carbon-support electrocatalyst, we investigate the carbon embedding of Pt cluster superlattices grown on the moiré of a monolayer of hexagonal boron nitride (h-BN) on Ir(111). Our combined scanning tunneling microscopy (STM) and X-ray photoelectron spectroscopy (XPS) study establishes conformal C embedding of the Pt clusters

Gatifloxacin induces S and G2-phase cell cycle arrest in pancreatic cancer cells via p21/p27/p53

Pancreatic cancer, despite being the most dreadful among gastrointestinal cancers, is poorly diagnosed, and further, the situation has been aggravated owing to acquired drug resistance against the single known drug therapy. While previous studies have highlighted the growth inhibitory effects of older generation fluoroquinolones, the current study aims to evaluate the growth inhibitory effects of

Lipid rafts in immune signalling: current progress and future perspective

Lipid rafts are dynamic assemblies of proteins and lipids that harbour many receptors and regulatory molecules and so act as a platform for signal transduction. They float freely within the liquid-disordered bilayer of cellular membranes and can cluster to form larger ordered domains. Alterations in lipid rafts are commonly found to be associated with the pathogenesis of several human diseases and

A detailed study on the micro-explosion of burning iron particles in hot oxidizing environments

As a promising carbon-free fuel, iron powder can directly combust with air and has great potential to provide clean and high-grad heat for various applications. The combustion characteristics of iron particles are of great significance for developing iron combustion model, designing efficient combustor, and optimizing combustion technologies. In this work, the micro-explosion behavior of burning i

Raman spectroscopy for characterizing porous carbon

Raman spectroscopy is performed to disclose structural properties of porous carbon samples including lignocellulosic biomass. Analysis of spectral signatures of carbon, around 1350 cm-1 and 1580 cm-1, indicates higher porosity for the biomass sample.

Factors affecting pandemic biosecurity behaviors of international travelers : Moderating roles of gender, age, and travel frequency

Research undertaken during the COVID‐19 pandemic has identified a number of significant factors that affect international travelers’ biosecurity behavior. Tourists’ age and gender as well as travel frequency have been found to have significant impacts on consumers’ non‐pharmaceutical intervention practices. However, despite the importance of age, gender, and travel frequency, such studies have ove

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

The advent of immune-checkpoint inhibitors (ICI) in modern oncology has significantly improved survival in several cancer settings. A subgroup of women with breast cancer (BC) has immunogenic infiltration of lymphocytes with expression of programmed death-ligand 1 (PD-L1). These patients may potentially benefit from ICI targeting the programmed death 1 (PD-1)/PD-L1 signaling axis. The use of tumor

Syntax-prosody mapping, topic-comment structure and stress-focus correspondence in Hungarian

This paper investigates the basic prosodic structure of Hungarian and its inter-action with information structure, in particular the following two aspects: the prosodic realization of the topic-comment partition, and the resolution of conflicts that may potentially arise between the basic algorithms of the syntax-prosody mapping on the one hand, and the prosodic requirement of the focus constituen

Innovating but still poor : The challenges of regional development in regions with mature industries

The persistence of patterns of decline or stagnation in developed countries has led to a renewed interest in the study of less developed regions. This renewed interest is informed by a variety of approaches, which range from studies on the unequal distribution of economic power and resources to analysis of regional endowments, such as human capital or quality of institutions. However, a persistent

Implementing an occupational therapy specific mental health intervention in a multi-professional context–the case of Balancing Everyday Life (BEL)

Background: The occupation-based intervention Balancing Everyday Life (BEL) was found effective under controlled conditions but should also be studied in a natural clinical practice context. Aim: The aim was to study the implementation process of BEL when provided in a multi-professional mental health team. The focus was particularly on how BEL was received and functioned. Methods: This qualitativ