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Poor postnatal growth after preterm birth does not match the normal rapid growth in utero and is associated with preterm morbidities. Insulin-like growth factor 1 (IGF-1) axis is the major hormonal mediator of growth in utero and levels of IGF-1 are often very low after preterm birth. We reviewed the role of IGF-1 in fetal development and the corresponding preterm perinatal period to highlight the
In this study, a method was developed for determination of steroid hormones (17beta-estradiol, estrone, 17alpha-ethynylestradiol) in tap and sewage water samples from Sweden. Sample preparation and analysis were performed by a hollow-fibre microporous membrane liquid-liquid extraction (HF-MMLLE) set-up combined with gas chromatography-mass spectrometry (GC-MS). In this approach, only the organic l
Background: In children with hypoplasia or aplasia of the radius (radial longitudinal deficiency) manual activity limitations may be caused by several factors; a short and bowed forearm, radial deviation of the wrist, a non-functional or absent thumb, limited range of motion in the fingers and impaired grip strength. The present study investigates the relation between these variables and activity
This paper presents a trans-disciplinary assessment of new and innovative biorefinery concepts producing high-value chemical compounds from residues from agriculture, food and forest industries. There is a significant potential of biomass residues in Sweden suitable for the extraction of various compounds, including upgrading by biocatalytic processes, in addition to current energy generation. Two
Parkinson’s Disease (PD) is a neurodegenerative disorder where the dopamine producing neurons in the ventral mesencephalon (VM) progressively die and result in symptoms such as resting tremors, muscle rigidity, slowness and difficulties in initiating movements.Currently there is no cure for PD and the available drug treatments only offer symptomatic relief and are often associated with severe side
Studies of 1H-NMR Relaxation Dispersion in Human Brain- tissue Samples: Implications for Magnetic Resonance Relaxation Dispersion Imaging (MARDI) Bertil R.R. Persson1, Lars Malmgren1,2 and Leif G. Salford3 1Medical Radiation Physics 2MAX Laboratory 3Dept. of Neurosurgery, Lund University, Lund Sweden [Bertil R.R. Persson, Lund University, Dept. of medical radiation physics, Barngatan 2, S-22185 Lu
Semiconductor III-V nanowires are promising components of future electronic and optoelectronic devices, but they typically show a mixed wurtzite-zinc blende crystal structure. Here we show, theoretically and experimentally, that the crystal structure dominates the conductivity in such InP nanowires. Undoped devices show very low conductivities and mobilities. The zincblende segments are quantum we
This thesis deals with manifold learning techniques and their application in gene expression data analysis. Manifold learning is the study of methods that aim to infer geometrical structure from data sampled from manifolds, enabling nonlinear solutions to various machine learning tasks. Gene expression data analysis is the analysis of measurements of the abundance of gene products from a set of ge
The predicted global warming may affect freshwater systems at several organizational levels, from organism to ecosystem. Specifically, in temperate regions, the projected increase of winter temperatures may have important effects on the over-winter biology of a range of organisms and especially for fish and other ectothermic animals. However, temperature effects on organisms may be directed strong
Abstract in UndeterminedThis paper addresses the use of ethnographic methods in the field known as family studies. While ethnographic methods are fundamental in the anthropological study of kinship and family, quantitative methods have long dominated family studies. To grasp the ideas and actions of human beings, however, we must pay attention to their intentions and recognize that intentions are
The up-converting ZrO2:Yb3+,E3+ nanomaterials were prepared with the combustion and sal-gel methods. The structure of the materials was cubic except for the minor monoclinic and tetragonal impurities associated with the use of the sal-gel method. The XANES results revealed only the trivalent form for both the Yb and Er dopants. The distance distributions calculated from EXAFS confirm that Er3+ and
Alzheimer's disease (AD) is the most common neurodegenerative disease, and is clinically characterized by cognitive disturbances and the accumulation of the amyloid beta (A beta) peptides in plaques in the brain. Recent studies have shown the links between AD and the immediate-early gene Arc (activity-regulated cytoskeleton-associated protein), involved in synaptic plasticity and memory consolidat
The report offers an analysis of the R&I system in Sweden for 2014, including relevant policies and funding, with particular focus on topics critical for two EU policies: the European Research Area and the Innovation Union. The report was prepared according to a set of guidelines for collecting and analysing a range of materials, including policy documents, statistics, evaluation reports, webs
Aims/Hypothesis: HLA genes, islet autoantibodies and residual C-peptide were studied to determine the independent association of each exposure with diabetic retinopathy (DR), 15 years after the clinical onset of type 1 diabetes in 15-34 year old individuals. Methods: The cohort was identified in 1992 and 1993 by the Diabetes Incidence Study in Sweden (DISS), which investigates incident cases of di
The overall aim of this thesis was to study different aspects of health on a population based level for persons with four common forms of cancer and their partners, and from an individual level to explore the impact on the daily life situation of living with advanced colorectal cancer for persons with cancer and their partners. Population based register data was used to compare different aspects o
