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A Continuum Theory of Phase Separation Kinetics for Active Brownian Particles

Active Brownian particles (ABPs), when subject to purely repulsive interactions, are known to undergo activity-induced phase separation broadly resembling an equilibrium (attraction-induced) gas-liquid coexistence. Here we present an accurate continuum theory for the dynamics of phase-separating ABPs, derived by direct coarse-graining, capturing leading-order density gradient terms alongside an ef

Biogeography of bacterial communities exposed to progressive long-term environmental change

The response of microbial communities to long-term environmental change is poorly understood. Here, we study bacterioplankton communities in a unique system of coastal Antarctic lakes that were exposed to progressive long-term environmental change, using 454 pyrosequencing of the 16S rDNA gene (V3-V4 regions). At the time of formation, most of the studied lakes harbored marine-coastal microbial co

Leisure repertoire among persons with a spinal cord injury: Interests, performance, and well-being

Objective: To explore and describe the leisure repertoire of persons with traumatic spinal cord injury (SCI) and how the repertoire is related to interest, performance, and well-being. Design: Cross-sectional study. Setting: A total of 97 persons with traumatic SCI were recruited from the non-profit national organization, RG Active Rehabilitation in Sweden. Outcome measure: Data were collected thr

Discriminating and Simulating Actions with the Associative Self-Organizing Map

Abstract in UndeterminedWe propose a system able to represent others' actions as well as to internally simulate their likely continuation from a partial observation. The approach presented here is the first step towards a more ambitious goal of endowing an artificial agent with the ability to recognise and predict others' intentions. Our approach is based on the associative self-organising map, a

Connecting Inflammation with Glutamate Agonism in Suicidality

The NMDA-receptor antagonist ketamine has proven efficient in reducing symptoms of suicidality, although the mechanisms explaining this effect have not been detailed in psychiatric patients. Recent evidence points towards a low-grade inflammation in brains of suicide victims. Inflammation leads to production of quinolinic acid (QUIN) and kynurenic acid (KYNA), an agonist and antagonist of the glut

Dynamic Jahn-Teller Effect in the Metastable High-Spin State of Solvated [Fe(terpy)(2)](2+)

Characterizing structural distortions in the metastable spin states of d(4)d(7) transition metal ion complexes is crucial to understand the nature of their bistability and eventually control their switching dynamics. In particular, the impact of the JahnTeller effect needs to be assessed for any electronic configuration that could be effectively degenerate, as in e.g. the high-spin (HS) manifold o

Italian and Nordic social workers’ assessments of families with children at risk

The question of how social workers view child welfare problems and what are seen as appropriate interventions has been subject of debate and research the last decades. The aim of the study is to investigate how different child welfare models influence social workers’ assessment of cases involving children at risk. This is done by identifying differences and similarities between Nordic and Italian

Structure and Function of Cu(I)- and Zn(II)-ATPases

Copper and zinc are micronutrients essential for the function of many enzymes while also being toxic at elevated concentrations. Cu(I)- and Zn(II)-transporting P-type ATPases of subclass 1B are of key importance for the homeostasis of these transition metals, allowing ion transport across cellular membranes at the expense of ATP. Recent biochemical studies and crystal structures have significantly

Visualization of subcutaneous insulin injections by x-ray computed tomography

We report how the three-dimensional structure of subcutaneous injections of soluble insulin can be visualized by x-ray computed tomography using an iodine based contrast agent. The injections investigated are performed ex vivo in porcine adipose tissue. Full tomography scans carried out at a laboratory x-ray source with a total acquisition time of about 1 min yield CT-images with an effective pixe

Allogeneic haematopoietic stem-cell transplantation with reduced intensity conditioning for advanced stage Hodgkin's lymphoma in Sweden: high incidence of post transplant lymphoproliferative disorder

Allogeneic transplantation after reduced intensity conditioning (allo-RIC) is a treatment option for patients with Hodgkin's lymphoma (HL) relapsing after autologous transplantation. In all, 23 adult patients with HL underwent allo-RIC in Sweden between 2000 and 2007. The median number of previous treatment lines was five and 20 patients (87%) were previously autografted. TRM at 100 days and at 1

Theorising intersectionality and sexuality

In the light of the critique that intersectionality demands and reproduces static identity categories, the editors of Theorising intersectionality and sexuality, Yvette Taylor, Sally Hines and Mark E. Casey, and with them the authors of the 12 texts in the book, assert the usefulness of ‘claims making, entitlements and “rights” of situated sexual citizens’ (3), if it is connected to empirical work

Transcriptome analysis of Stagonospora nodorum: gene models, effectors, metabolism and pantothenate dispensability.

The wheat pathogen Stagonospora nodorum, causal organism of the wheat disease Stagonospora nodorum blotch, has emerged as a model for the Dothideomycetes, a large fungal taxon that includes many important plant pathogens. The initial annotation of the genome assembly included 16 586 nuclear gene models. These gene models were used to design a microarray that has been interrogated with labelled tra

Phenotypic ASCO Characterisation of Young Patients with Ischemic Stroke in the Prospective Multicentre Observational sifap1 Study

Background: The prospective, multinational European 'Stroke in Young Fabry Patients' (sifap1) study collected 4,467 patients with acute ischemic cerebrovascular events aged 18-55 years. Initially, aetiologic subtyping was performed using the TOAST classification; however, recently the phenotypic ASCO classification was presented and might be more useful to identify stroke aetiologies in young pati

A Molecular Mechanism for the Water-Hydroxyl Balance during Wetting of TiO2

We show that the formation of the wetting layer and the experimentally observed continuous shift of the H2O-OH balance toward molecular water at increasing coverage on a TiO2(110) surface can be rationalized on a molecular level. The mechanism is based on the initial formation of stable hydroxyl pairs, a repulsive interaction between these pairs, and an attractive interaction with respect to water

Does Cash Flow Predict Returns?

In this paper, we propose the hypothesis that cash flow and cash flow volatility predict returns. We categorize firms listed on the New York Stock Exchange into sectors, and apply tests for both in-sample and out-of-sample predictability. While we find strong evidence that cash flow volatility predicts returns for all sectors, the evidence obtained when using cash flow as a predictor is relatively

Structure and kinetics of chemically cross-linked protein gels from small-angle X-ray scattering.

Glutaraldehyde (GA) reacts with amino groups in proteins, forming intermolecular cross-links that, at sufficiently high protein concentration, can transform a protein solution into a gel. Although GA has been used as a cross-linking reagent for decades, neither the cross-linking chemistry nor the microstructure of the resulting protein gel have been clearly established. Here we use small-angle X-r