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Scaling behaviours of deep learning and linear algorithms for the prediction of stroke severity

Deep learning has allowed for remarkable progress in many medical scenarios. Deep learning prediction models often require 105–107 examples. It is currently unknown whether deep learning can also enhance predictions of symptoms post-stroke in real-world samples of stroke patients that are often several magnitudes smaller. Such stroke outcome predictions however could be particularly instrumental i

Regulation of insulin secretion in diabetes: Molecular mechanism and applications

Diabetes is a highly ageing-related disease manifesting with a deteriorated capacity of insulin secretion and uncontrolled blood glucose-raising, hyperglycemia. In this thesis, we aim to explore the underlying roles of CaV channels and aging-associated genetic changes in the development of Type 2 diabetes (T2D).In pancreatic β-cells, the active of voltage-gated calcium (CaV) channels play an essen

Målningars påverkan av samhällsprocesser

The paper is about how society effects art when society goes through different social processes. The study is limited to the period referred to as the Vasa era and to paintings. What is meant with Vasa era is the 16th century. During that period, society goes through a social centralization in Europe and the question arises if this is, or becomes, noticeable in the art. This is another angle on so

Frankenstein and the Timelessness of Queer Identities: Teaching Mary Shelley’s Frankenstein through Queer Theory in the Upper-Secondary EFL classroom

This paper analyses the pivotal gothic novel Frankenstein by Mary Shelley through a close queer reading, focusing on excerpts featuring the artificially created creature and their maker, Victor Frankenstein. The queer perspective is applied to the gender identity and expression of the creature, which is a reading that lends itself to the teaching of the novel to Swedish upper-secondary students be

Analyses of crucibles from southern and western Sweden using handheld XRF

In this article some initial results from the projects "Bronsildems deglar" (en. "Bronze Age melting crucibles") and "Deglarna frin Bokenäs" (en. "The crucibles from Bokenäs") are presented. The aim of the projects is to expand our knowledge of the production, use and discard of technical ceramics in south Sweden using laboratory analysis. This article describes the results and conclusions made byIn this article some initial results from the projects "Bronsildems deglar" (en. "Bronze Age melting crucibles") and "Deglarna frin Bokenäs" (en. "The crucibles from Bokenäs") are presented. The aim of the projects is to expand our knowledge of the production, use and discard of technical ceramics in south Sweden using laboratory analysis. This article describes the results and conclusions made by

A Gradual Transition Toward Anaplasia in Wilms Tumor Through Tolerance to Genetic Damage

Patients with Wilms tumor (WT) in general have excellent survival, but the prognosis of patients belonging to the subgroup of WT with diffuse anaplasia (DA) is poor due to frequent resistance to chemotherapy. We hypothesized that DA WT cells might undergo changes, such as acquiring a persistent tolerance to DNA damage and copy number aberrations (CNAs), which could eventually lead to their resista

Social Status through Crucibles

This paper focuses on Bronze Age melting crucibles in southern Scandinavia. The shape and purpose of the crucibles have long been known, but the process of making one has not been studied thoroughly. The crucibles have in some cases been reconstructed in order to replicate the casting process or the finished product, but have rarely been the main subject of research. In this paper crucibles found

Wetlands as a potential multifunctioning tool to mitigate eutrophication and brownification

Eutrophication and brownification are ongoing environmental problems affecting aquatic ecosystems. Due to anthropogenic changes, increasing amounts of organic and inorganic compounds are entering aquatic systems from surrounding catchment areas, increasing both nutrients, total organic carbon (TOC), and water color with societal, as well as ecological consequences. Several studies have focused on

Impact of pre-biologic impairment on meeting domain-specific biologic responder definitions in patients with severe asthma

Background: There is little agreement on clinically useful criteria for identifying real-world responders to biologic treatments for asthma. Objective: To investigate the impact of pre-biologic impairment on meeting domain-specific biologic responder definitions in adults with severe asthma. Methods: This was a longitudinal, cohort study across 22 countries participating in the International Sever

Association between changed self-rated health and the risk of venous thromboembolism in Malmö Preventive Program : a cohort study

Poor self-rated health (SRH) is associated with incident arterial cardiovascular disease in both sexes. Studies on the association between SRH and incident venous thromboembolism (VTE) show divergent results in women and no association in men. This study focuses on the association between change in SRH and incident VTE in a cohort of 11,558 men and 6682 women who underwent a baseline examination a

Phygital time geography, or: what about technology in tourists' space-time behaviour?

Artikeln argumenterar för en förnyad relevansen för tidsgeografi iturism i ljuset av mobil teknikanvändning och allestädes närvarandedigital uppkoppling. Uppsatsen föreslår begreppet fygitalitet för attförstå hur digital teknik används i det fysiska rummet, ochhur samspelet mellan det fysiska och det digitala omformasi turisters projekt, rutter, kopplingar och begränsningar. Det teoretiskabidragetThe paper argues for the renewed relevance of time geography in tourism in light of the use of mobile technologies and ubiquitous connectivity. The paper proposes the concept of phygitality to understand how digital technologies are used in physical space, and how the interaction between the physical and the digital reconfigures tourists’ projects, paths, bundles, and constraints. The theoretical

Characterization of MdpS : an in-depth analysis of a MUC5B-degrading protease from Streptococcus oralis

Oral biofilms, comprising hundreds of bacteria and other microorganisms on oral mucosal and dental surfaces, play a central role in oral health and disease dynamics. Streptococcus oralis, a key constituent of these biofilms, contributes significantly to the formation of which, serving as an early colonizer and microcolony scaffold. The interaction between S. oralis and the orally predominant mucin

Tensions affecting law teachers’ collaborative practice around teaching : a study of beliefs and practices

Collaborative practice among teachers, where teachers collaborate around their teaching practice, is known to optimise student learning in primary and secondary schools, where they are encouraged to create shared conceptions of vision, purpose and means. In higher education, however, studies on teachers working as teams and abandoning traditional norms of isolation and individualism around teachin

Mitochondrial function in peripheral blood cells across the human lifespan

Mitochondrial dysfunction is considered a hallmark of aging. Up to now, a gradual decline of mitochondrial respiration with advancing age has mainly been demonstrated in human muscle tissue. A handful of studies have examined age-related mitochondrial dysfunction in human blood cells, and only with small sample sizes and mainly in platelets. In this study, we analyzed mitochondrial respiration in

Deep learning performance on MRI prostate gland segmentation : evaluation of two commercially available algorithms compared with an expert radiologist

PURPOSE: Accurate whole-gland prostate segmentation is crucial for successful ultrasound-MRI fusion biopsy, focal cancer treatment, and radiation therapy techniques. Commercially available artificial intelligence (AI) models, using deep learning algorithms (DLAs) for prostate gland segmentation, are rapidly increasing in numbers. Typically, their performance in a true clinical context is scarcely

Slaggrus och dammspridning från anläggningsarbete

Vid förbränning av avfall produceras stora mängder slaggrus som både är ett avfall, som kräver hantering, och en resurs, genom dess goda materialegenskaper. Slaggrus definieras i denna studie som sorterad bottenaska från avfallsförbränning. En potentiell spridningsväg för föroreningar från slaggruset vid anläggningsarbete är damning. Damning är en miljöoch hälsofara även utan föroreningar i materi

Equivalence and polyvalence : A case for the stratification of semantics

The article presents a semantic theory suggesting that equivalence and polyvalence are closely connected phenomena. The connection between them is utilised by making equivalence the basis of an argument for polyvalence within semantics, or in other terms, for a stratified semantics encompassing two levels of description. This argument from equivalence lends new support to frameworks assuming a str