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Background: Stickler syndrome is a hereditary disorder of collagen tissues causing ocular, auditory, orofacial, and joint manifestations. Ocular findings typically include vitreous degeneration, high myopia, retinal detachment, and cataract. Many subjects demonstrate sensorineural or conductive hearing loss. The inheritance is autosomal dominant with mutations in COL2A1, COL11A1, or COL11A2 or aut
The Dapingian and lower Darriwilian graptolite succession of the Krapperup drill core from Scania, southern Sweden, provides a detailed insight into the axonophoran (biserial) graptolites and their early Palaeozoic evolutionary changes on the Scandinavian platform. Even though earliest Darriwilian axonophorans are not represented, the succession includes faunal elements of the basal Darriwilian Ar
Controlling infinite dimensional models remains a challenging task for many practitioners since they are not suitable for traditional control design techniques or will result in a high-order controller too complex for implementation. Therefore, the model or the controller need to be reduced to an acceptable dimension, which is time-consuming, requires some expertise and may introduce numerical err
Purpose: Speech-language pathologists’ (SLPs) role in tracheostomy management is well described internationally. Surveys from Australia and the United Kingdom show high clinical consistency in SLP tracheostomy management, and that practice follows guidelines, research evidence and protocols. Swedish SLPs work with tracheostomised patients, however, the content and extent of this practice, and how
Introduction: COPD is a major cause of morbidity and mortality. The prevalence, morbidity and mortality of COPD among females have increased. Previous studies indicate a possible gender bias in the diagnosis and management of COPD. The present study aims to determine if there is gender bias in the management of COPD in Sweden.Methods: This was a double-blind, randomised (1:1), controlled, parallel
Background: Asthma exacerbations are commonly associated with rhinovirus (RV) infection. Interleukin-33 (IL-33) plays an important role during exacerbation by enhancing Type 2 inflammation. Recently we showed that RV infects bronchial smooth muscle cells (BSMCs) triggering production of interferons and IL-33. Here we compared levels of RV-induced IL-33 in BSMCs from healthy and asthmatic subjects,
Interaction of immunoglobulin G (IgG)-coated latex particles with Fc receptors on myeloid leukemic blood cells and on polymorphonuclear granulocytes (PMN) from remission patients and healthy blood donors was investigated using microcalorimetry. The induced heat production by leukemic cells from 13 patients with the M2, M4 and M5 FAB groups (French-American-British classification) of acute myeloid
Increasing human impact on the environment is causing drastic changes in disturbance regimes and how they prevail over time. Of increasing relevance is to further our understanding on biological responses to pulse disturbances (short duration) and how they interact with other ongoing press disturbances (constantly present). Because the temporal and spatial contexts of single experiments often limi
The effect of granulocytes on human platelet aggregation was investigated in vitro. Platelet function was assayed by photometric technique. Incubation of platelets with latex-stimulated granulocytes for 1 h at room temperature resulted in total inhibition of arachidonic acid-induced platelet aggregation. ADP-induced platelet aggregation was suppressed, lacked secondary wave and was pursued by swif
This cross-country comparison of administrative responses to the COVID-19 pandemic in France, Germany and Sweden is aimed at exploring how institutional contexts and administrative cultures have shaped strategies of problem-solving and governance modes during the pandemic, and to what extent the crisis has been used for opportunity management. The article shows that in France, the central governme
Microcalorimetry using a 4-channel static ampoule microcalorimeter of thermopile type has been evaluated as a tool for the detection of complement-dependent cytotoxicity against the surface antigens of living cells. Cytotoxic reactions mediated by a rabbit antiserum against human white blood cells and by 2 different monoclonal antibodies recognizing a melanoma-associated antigen on a human melanom
Today, engineered nanomaterials are frequently used. Nanosized titanium dioxide (TiO2) has been extensively used for many years and graphene is one type of emerging nanomaterial. Occupational airborne exposures to engineered nanomaterials are important to ensure safe workplaces and to extend the information needed for complete risk assessments. The main aim of this study was to characterize workpl
Background: The most profound effect of vasopressin on the kidney is to increase water reabsorption through V2-receptor (V2R) stimulation, but there are also data suggesting effects on calcium transport. To address this issue, we have established an isolated perfused kidney model with accurate pressure control, to directly study the effects of V2R stimulation on kidney function, isolated from syst
Odd-frequency (odd−ω) electron pair correlations naturally appear at the interface between BCS superconductors and other materials. The detection of odd−ω pairs, which are necessarily nonlocal in time, is still an open problem. The main reason is that they do not contribute to static measurements described by time-local correlation functions. Therefore, dynamical measurements, which depend on nonl
Q-design is a powerful method for designing approximately optimal LTI controllers and assessing the achievable control performance. Unfortunately, numerical issues are often encountered in Q-design which limits its applicability. This paper warns about two numerical pitfalls in Q-design when using H 2 costs and Laguerre-type basis functions.
Elastic and scalable compute resources are a fundamental part of cloud computing. Efficient management of cloud resources is crucial in order to provide high quality services and applications. In this work we present a novel method for scaling cloud resources and provide stability guarantees. We do this by leveraging ideas and concepts from classic control theory, namely mid-range control and combElastic and scalable compute resources are a fundamental part of cloud computing. Efficient management of cloud resources is crucial in order to provide high quality services and applications. In this work we present a novel method for scaling cloud resources and provide stability guarantees. We do this by leveraging ideas and concepts from classic control theory, namely mid-range control and comb
Studies of degrowth in tourism have shed light on the phenomenon of lifestyle entrepreneurship, often highlighting these businesses as examples of alternative, non-growth oriented production. This chapter focuses on two examples of lifestyle oriented animal-based tourism in Sweden: horse-related tourism and hunting tourism. It is argued that these enterprises are engaged in decommodification pract
