The rapid advance in our understanding of cancer biology during the past decade, as exemplified by the discovery of oncogenes and tumour suppressor genes and their interactions in tumourigenesis, has revolutionized cancer research. This rapid progress has largely been due to the use of molecular genetics techniques. However, despite the wealth of available information as to the genetic basis of ca

The bioelectrocatalytic function of two plant peroxidases, horseradish peroxidase (HRP) and a newly purified royal palm tree-leaf peroxidase (RPTP), was studied on graphite electrodes in aqueous buffer solutions, over the pH range 7.0 - 3.0, and in aqueous buffer solutions, at pH 6.0, containing different amounts of a polar organic cosolvent, i.e., ethanol and acetonitrile. The kinetics of direct

List-sequence (LS) decoding has the potential to yield significant coding gain additional to that of conventional single-sequence decoding, and it can be implemented with full backward compatibility in systems where an error-detecting code is concatenated with an error-correcting code. LS maximum-likelihood (ML) decoding provides a list of estimated sequences in likelihood order. For convolutional

Liquid chromatography mass spectrometry (LC-MS) is a valuable tool in the analysis of proteins and peptides. The combination of LC-MS with different fragmentation methods provides sequence information on components in complex mixtures. In this work, on-line packed capillary LC electrospray ionization Fourier transform ion cyclotron resonance MS was combined with two complementary fragmentation tec

The crepuscular nymphalid butterfly Manataria maculata was studied in Monteverde cloud forest, Costa Rica, during the dry season reproductive diapause. M. maculata has ears in the form of Vogel's organs located near the base of the forewings. Its behaviour in response to bursts of ultrasonic pulses (26 kHz, 110 dB SPL at 1 m) was condition-dependent. At dusk and dawn the sound consistently elicite

Fördelning av optimal värmeisolering runt en byggnads ytterhölje speciellt m h t värmeflödet mot mark.

We investigate the noise properties of a zero-dimensional InAs quantum dot (QD) embedded in a GaAs-AlAs-GaAs tunneling structure. We observe an approximately linear dependence of the Fano factor and the current as a function of bias voltage. Both effects can be linked to the scanning of the three-dimensional emitter density of states by the QD. At the current step the shape of the Fano factor is m

Popular Abstract in Swedish Avhandlingen omfattar studiet av fossila pollen och sporer (palynologi) från skånes krita (90-140 miljoner år gamla sediment). För ändamålet har tre borrkärnor provtagits; Höllviken 2, Norrevång 1 och Svedala 1, samt ytprover från överkritan på Bornholm. RESULTAT * Taxonomiska studier baserade på ca 100 arter (ca. 15 000 exemplar), har möjliggjort en stratigrafisk indeA palynological investigation of Cretaceous sequences from Höllviken 2, Svedala 1 and Norrevång 1 wells of Scania, Southern Sweden, and from the Arnager Greensand-Arnager Limestone transition on the island of Bornholm, Denmark, was conducted. Well preserved palynofloras were found in strata consisting of shaly mudstones, glauconitic sandstones (greensand) and limestone. A total of 98 palynomorph t

Jämviktsprovtagning genom membran är ett nytt koncept där porösa hålfibrer används för upprening, anrikning och mätning av polära organiska föreningar och metaller. Metoden kan användas såväl i laboratoriet som till fältprovtagning

To gain insight into the mechanisms responsible for the loss of the glucagon response to insulin-induced hypoglycemia in type 1 diabetes, glucagon responses to 4 different stimuli were examined over 3 months of diabetes in alloxan-treated mice. At 1, 6, and 12 weeks after alloxan (60 mg/kg), phloridzin (0.1 g/kg) was administered to overnight fasted diabetic mice to match the glucose levels of tho

Utgångspunkten för projektet Skåne i god form II har varit de problem på arbetsmarknaden som kan relateras till arbetsmiljön och som resulterar i hög sjukfrånvaro och svårigheter att behålla och nyrekrytera arbetskraft. Projektet har syftat till att skapa möjligheter för de anställda att tillsammans med designer granska sin egen arbetsmiljö och de arbetsuppgifter man har och utarbeta förslag på hu

If individuals occupy habitats in a way that maximizes their fitness, if they are free to occupy the habitats they choose and if fitness declines with population density, then their abundance across habitats should follow an ideal free distribution. But, if individuals are genetically related, this simple fitness-maximization mechanism breaks down. Habitat occupation should obey Hamiltons rule (na

Observations of the ultra-sharp-lined HgMn star chi Lupi made with the Goddard High Resolution Spectrograph after the Hubble Space Telescope First Servicing Mission display the effect of COSTAR corrective optics upon the spectral resolution of several observing modes. The resolution is restored to levels expected in the absence of the telescope spherical aberration for all observations made throug

In a large variety of disciplines, fundamental studies often straddle in self-referential situations, in need of relativization to language and complementaristic resolution. In such attempts, the languages at play are hardly visible themselves. Only shadows of language, somewhat characteristic of the various disciplines, become visible and tractable. We select two domains, quantum mechanics and cy

Intramuscular triacylglycerol is an important energy store and is also related to insulin resistance. The mobilization of fatty acids from this pool is probably regulated by hormone-sensitive lipase (HSL), which has recently been shown to exist in muscle and to be activated by both adrenaline and contractions. Adrenaline acts via cAMP-dependent protein kinase (PKA). The signalling mediating the ef

PURPOSE: To determine the normal values of the anterior and posterior capsular distances of the hip joint in healthy children by means of US, using MR imaging as reference, and to evaluate any possible correlation between age, length, weight and anterior capsular distance (ACD). MATERIAL AND METHODS: In our first study both hips in 14 healthy children (5-18 years old) were examined with US and MR