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Prostate cancer polygenic risk score and prediction of lethal prostate cancer

Polygenic risk scores (PRS) for prostate cancer incidence have been proposed to optimize prostate cancer screening. Prediction of lethal prostate cancer is key to any stratified screening program to avoid excessive overdiagnosis. Herein, PRS for incident prostate cancer was evaluated in two population-based cohorts of unscreened middle-aged men linked to cancer and death registries: the Västerbott

Repair-related molecular changes during recovery phase of ischemic stroke in female rats

Background: Some degree of spontaneous recovery is usually observed after stroke. Experimental studies have provided information about molecular mechanisms underlying this recovery. However, the majority of pre-clinical stroke studies are performed in male rodents, and females are not well studied. This is a clear discrepancy when considering the clinical situation. Thus, it is important to includ

Continuous-Time Model Identification and State Estimation Using Non-Uniformly Sampled Data

This paper presents theory, algorithms and validation results for system identification of continuous-time state-space models from finite non-uniformly sampled input-output sequences. The algorithms developed are methods of model identification and stochastic realization adapted to the continuous-time model context using non-uniformly sampled input-output data. The resulting model can be decompose

Plastic policies : Contemporary opportunities and challenges in public libraries’ enactment of cultural policy

This study explores how democracy—often understood as an abstract concept or a location- transcending, intangible phenomenon—is produced, shaped and continuously reshaped through local library practices in certain places and under local conditions at a specific point in time. To better understand potential conflicts and/or tensions that might arise between the three levels of Swedish library polic

A Fast Physical NOx Model Implemented on an Embedded System

This paper offers a two-zone, physical, NOx model with low computational cost, implemented in C on an embedded system. The model is able to compute NOx-emission formation with high time resolution during an engine cycle. To do this the model takes cylinder pressure and injected fuel amount as inputs and produces NO concentration as output. The model as such is not new, nevertheless the physical ba

Subspace-Based Model Identification of Diabetic Blood Glucose Dynamics

The paper describes an on-line identification algorithm to estimate the steam production of a municipal solid waste incinerator. The algorithm has to learn on-line the system dynamics due to the heavy disturbances acting on the incineration process. The learning algorithm is based on radial basis function networks and combines the growth criterion of the resource allocating network technique with

Lärdomar om öppenhet: : EndNote-kurs som öppen lärresurs

Bakgrund: I samband med en workshop om att jobba i lärplattformen Canvas så inledde tre bibliotekarie vid Lunds universitet ett projekt att skapa en resurs för referenshanteringsprogrammet EndNote. Vi började i januari 2020 och lanserade vår Canvas-kurs med EndNote X9 i augusti 2020. Under 2021 uppdaterades hela kursen för att anpassas till EndNote 20.Syfte: Syftet var att täcka en lucka, då vi sa

Preschool Children’s Inhalation Rates Estimated from Accelerometers—A Tool to Estimate Children’s Exposure to Air Pollution

Children are particularly sensitive to air pollution exposure, and their personal exposures may differ significantly from those of adults. One key factor for understanding the personal inhaled dose of air pollutants is the respiratory minute ventilation (Ve). To estimate the amount of particles circulated through the lungs, 24 h averages of Ve are often used. These averages poorly capture variatio

Estimation and Direct Adaptive Control of Delay-Differential Systems

The problem of adaptive prediction and direct adaptive control for systems described by delay-differential systems is considered. A model reference approach to direct adaptive control is shown to be feasible for a class of 2-D systems. A reparametrization of the 2-D system description is given and the identification problem is converted into a linear estimation problem. Some necessary conditions f