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Construction of a frailty index as a novel health measure in systemic lupus erythematosus

Objective. To construct a Frailty Index (FI) as a measure of vulnerability to adverse outcomes among patients with systemic lupus erythematosus (SLE), using data from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort. Methods. The SLICC inception cohort consists of recently diagnosed patients with SLE followed annually with clinical and laboratory assessments. For thi

Butyrate producing colonic Clostridiales metabolise human milk oligosaccharides and cross feed on mucin via conserved pathways

The early life human gut microbiota exerts life-long health effects on the host, but the mechanisms underpinning its assembly remain elusive. Particularly, the early colonization of Clostridiales from the Roseburia-Eubacterium group, associated with protection from colorectal cancer, immune- and metabolic disorders is enigmatic. Here, we describe catabolic pathways that support the growth of Roseb

Unexpected varus deformity and concomitant metal ion release and MRI findings of modular-neck hip stems : descriptive RSA study in 75 hips with 8 years’ follow-up

Background and purpose — Modular-neck hip stems have been identified with corrosion-related problems from the neck–stem junction. We report an ongoing varus deformity of modular-neck hip stems with simultaneous metal ion release observed during a study comparing the migration of modular vs. standard hip stems. Patients and methods — We followed 50 patients with modular and 25 with standard neck st

Development of a spatialized atmospheric emission inventory for the main industrial sources in Brazil

In this work, atmospheric pollutant emissions of NOx, SOx, CO, particulate matter (PM), total organic compounds (TOC), and CO2 from larger stationary sources of pollutants in Brazil were inventoried and spatialized over the whole Brazilian territory for the base year 2011. The developed inventory comprises a total of 16 refining units, 1730 thermoelectric power plants (TPPs), 96 cement industries,

LES study of diesel flame/wall interaction and mixing mechanisms at different wall distances

In this paper, the flame-wall interaction of reacting diesel spray under engine like conditions is investigated using large eddy simulations. The aim of this study is to understand the influence of the distance between the wall and the spray nozzle on the air entrainment rate, which is a key variable in formation/oxidation process of soot. Three experimental cases are investigated, a free jet case

Guidelines for conducting interactive rapid reviews in software engineering -- from a focus on technology transfer to knowledge exchange

Evidence-based software engineering (EBSE) aims to improve research utilization in practice. It relies on systematic methods (like systematic literature reviews, systematic mapping studies, and rapid reviews) to identify, appraise, and synthesize existing research findings to answer questions of interest. However, the lack of practitioners' involvement in the design, execution, and reporting of th

Murverkskonstruktion : Kompendium

Kompendiet är framtaget för att användas som lärobok i murverkskonstruktion på grundnivå på civil- och högskoleingenjörsutbildningar. Kompendiet behandlar dimensionering och konstruktiv utformning av murverkskonstruktioner i enlighet med Eurokod 6 samt den svenska nationella bilagan EKS 11 och kan därmed även användas av yrkesverksamma konstruktörer. För en mer uttömmande hantering av konstruktion

Strengthened clay brick and lightweight aggregate concrete block walls tested under eccentric axial loading – a feasibility study on different strengthening techniques

Strengthening of masonry walls is a means to improve the energy performance of modern external masonry walls without further increasing their total thickness. The present paper evaluates the feasibility - here refer-ring to ease-of-application and structural performance - of several techniques aimed at strengthening mason-ry walls subjected to eccentric axial loading. Four full scale walls made of

Energi- och resurseffektiva murade ytterväggar

EUs Energieffektiviseringsdirektiv innebär en skärpning av kraven på byggnaders energiprestanda. För murverksbranschens del har man identifierat ett behov av att utveckla ytterväggskonstruktioner med 30 procent lägre U-värde jämfört med idag vanligt förekommande murade ytterväggslösningar. Utveckling av välisolerade murade ytterväggskonstruktioner med tunna, ytförstärkta bärande delar förefaller v

Ceramic Transition and Actor-Network Theory : The Gyllenkrok House, Lund

During the 12th and 13th centuries the pottery assemblages inScandinavia changed from hand-formed into wheel-thrown pottery. Thistransition has not caught much interest among scholars and has usuallybeen explained with economic and functionalistic perspectives. Usingactor-network theory, as applied by Astrid Van Oyen, this paper discussesthe problem of how and why this ceramic transition happened.

Energieffektiva murade väggar med slimmad tjocklek

Glasfibernät och stål som appliceras i putsen eller fästes mekaniskt direkt mot väggytan möjliggör en minskning av den bärande väggens tjocklek i murade ytterväggar. Det insparade utrymmet kan användas till mer isolering och därmed bygga mer energieffektiva murade ytterväggar utan att öka den totala väggtjockleken. Väggarnas klimatavtryck minskar.

Omfogning av tegelfasader

En översiktlig uppskattning visar att man i Sverige årligen lägger flera hundra miljoner kronor på omfogning av tegelfasader. Beslut om underhåll baseras ofta på generella mallar, utan hänsyn till det aktuella behovet. Detta medför onödigt stora utgifter samtidigt som omfogning är ett slitsamt arbete. Ett doktorandprojekt vid Lunds tekniska högskola avser ge utökad kunskap om när omfogning är rati

Work

Work is drudgery for a lot of people, whether physically or mentally, as they have to work a lot to make a living. Despite this, the work we do defines how we are perceived in society, while precarity of work has become the norm. A lot of work in capitalist growth-oriented economies is also environmentally and socially destructive. However, work can be different and meaningful, if radically reorga

Review: Methods for Studying Video Games and Religion

The edited volume Methods for Studying Video Games and Religion (2017) by Vít Šisler, Kerstin Radde-Antweiler, and Xenia Zeiler takes the study of religion and video games seriously and recognizes the widespread usage of religious themes in the world of games. The book can be read as an exposé of the state of research in the field of Game Studies with the specific focus on methods for researching The edited volume Methods for Studying Video Games and Religion (2017) by Vít Šisler, Kerstin Radde-Antweiler, and Xenia Zeiler takes the study of religion and video games seriously and recognizes the widespread usage of religious themes in the world of games. The book can be read as an exposé of the state of research in the field of Game Stud-ies with the specific focus on methods for researching

Health Care Staff's Experiences of Engagement When Introducing a Digital Decision Support System for Wound Management : Qualitative Study

BACKGROUND: eHealth solutions such as digital decision support systems (DDSSs) have the potential to assist collaboration between health care staff to improve matters for specific patient groups. Patients with hard-to-heal ulcers have long healing times because of a lack of guidelines for structured diagnosis, treatment, and follow-up. Multidisciplinary collaboration in wound management teams is e

Treatment of organic pollutants in high salinity wastewater : new catalysis systems

High salinity wastewater (HSW, NaCl mass fraction ≥ 1%) from industries and aquacultures contains massive organic matters with a wide variety. These organic matters have been considered as significant threaten to both human and environment. The removal and degradation of them before discharge emerge as necessity. However, the traditional treatment methods show significant drawbacks for this purpos