Monoclonal antibodies for targeting cytotoxic conjugates to tumor cells are currently being evaluated together with extracorporeal affinity adsorption. The aim of the adsorption was to reduce undesired side effects in normal organs and to increase the tumor-to-normal tissue ratios. This technique is also applicable to several other therapeutic areas such as immune-mediated disorders, that is, auto

Popular Abstract in Swedish Populärvetenskaplig sammanfattning på svenska (Comprehensive summary in Swedish) Uppföljning av blodtryck (BT), medicinering och njurfunktion efter endovaskulär behandling av njurartärsteno's Bakgrund Förträngning av njuren's tillförande blodkärl, njurartärsteno's (RAS), är den vanligaste sekundära formen av högt BT (hypertension) och svarar för ca 1-5% av hypertensiRenal artery stenosis (RAS) causes hypertension, decreased glomerular filteration rate (GFR), and renal ischemia. RAS is progressive and causes 5-16% of all cases of renal failure. Prevalence of RAS in patients with hypertension is 1-5%. Today percutaneous transluminal renal angioplasty (PTRA) with or without stenting is a widely accepted treatment of RAS. Treatment of renal artery occlusion (RAO)

BACKGROUND AND PURPOSE: It is unclear whether stroke in patients with spontaneous dissection of the cervical internal carotid artery (ICAD) is due to thromboembolism or impaired hemodynamics. This study investigated the mechanism of stroke in ICAD by examining brain imaging and cerebrovascular findings of such patients. METHODS: We retrospectively evaluated the prospectively collected brain CT, MR

This paper describes a radio-tracking study of Osmoderma eremita, a large Scarabaeid beetle, living in hollow trees. The study seems to be the first in which radio telemetry has been used with a flying insect in the field. Some 74 adult beetles were tagged with radio transmitters weighing 0.48-0.52 1, and having a nominal battery life of 12-20 days. Transmissions were detected at ranges of up to 3

I denna artikel diskuteras och problematiseras nordisk forskning med inriktning mot konsumtion och fattigdom. Då forskningen inom detta fält förekommer inom flera vetenskapliga discipliner beskrivs några centrala perspektiv. Härefter problematiseras befintlig forskning, såväl i förhållande till dess innehåll som till dess hitintills svaga etablering. Vidare ges förslag på utvecklingsmöjligheter.

BCS1L is a chaperone necessary for the incorporation of Rieske Fes and Qcr10p into complex III (CIII) of the respiratory chain. Mutations in the BCS1L gene cause early fetal growth restriction and a lethal neonatal disease in humans, however, the pathogenesis remains unclear. Here, we analysed the expression of BCS1L during mouse embryonic development and compared its expression with that of the m

Interactions between two ectomycorrhizal fungal species, Piloderma croceum Erikss. and Hjortst. and Piloderma sp. 1 (found to colonise spruce roots and wood ash granules in the field), were investigated in wood ash amended substrates. The comparative ability of these fungi to colonise roots of non-mycorrhizal spruce (Picea abies (L.) Karst.) seedlings was studied in relation to factorial combinati

Department of Occupational and Environmental Medicine, Institute of Laboratory Medicine, Lund University Hospital, S-221 85 Lund, Sweden. The aim of this study was to investigate if the uptake of N-methyl-2-pyrrolidone (NMP), a widely used industrial chemical, increases after exposure to NMP in humid air compared to dry air. NMP has been described to be an airway irritant and a developmentally to