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Effects of exercise training in predialytic uremic patients

We examined the effects of physical training in 10 predialytic uremic patients (7 men, 3 women, mean age 47 ± 8 years) with an average glomerular filtration (GFR) of 15 ± 7 ml/min x 1.73 m2. All 10 patients participated in an exercise programme 3 times/week for 3 months and were compared to a control group of 9 patients with comparable baseline variables. The exercise group increased its maximal e

Polarization effects in the central exclusive χc production and the J/ψ angular distributions

We discuss exclusive elastic double diffractive axial-vector χc(1+) and tensor χc(2+) mesons production for different meson polarizations in proton-(anti)proton collisions at the Tevatron energy. The amplitude for the process is derived within the kt-factorization approach using unintegrated gluon distributions. Differential cross sections for different χc polarizations are calculated. Angular dis

Precarious employment is a risk factor for poor mental health in young individuals in Sweden : A cohort study with multiple follow-ups

Background: The globalisation of the economy and the labour markets has resulted in a growing proportion of individuals who find themselves in a precarious labour market situation, especially among the young. This pertains also to the Nordic countries, despite their characterisation as well developed welfare states with active labour market policies. This should be viewed against the background of

Measuring the health-related Sustainable Development Goals in 188 countries : a baseline analysis from the Global Burden of Disease Study 2015

BACKGROUND: In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 health-related SDG indicators based on the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015).METHODS: We applied statistical methods to systematic

Exploitation of Natural Resources and Protection of Indigenous Peoples’ Communal Property over Traditional Lands and Territories : A summary of the Inter-American Court of Human Rights’ safeguards

This summary critically analyses the legal regime that protects the ancestral lands and natural resources traditionally used, the so-called traditional communal property, of indigenous and tribal peoples in the Americas. It also analyses the legal regime’s connection with indigenous and tribal people’s right to cultural identity and the right to a dignified life.The Inter-American Court of Human R

Stem cell gene expression programs influence clinical outcome in human leukemia

Xenograft studies indicate that some solid tumors and leukemias are organized as cellular hierarchies sustained by cancer stem cells (CSCs). Despite the promise of the CSC model, its relevance in humans remains uncertain. Here we show that acute myeloid leukemia (AML) follows a CSC model on the basis of sorting multiple populations from each of 16 primary human AML samples and identifying which co

Distinct differences in association of MHC class I with endoplasmic reticulum proteins in wild-type, and beta 2-microglobulin- and TAP-deficient cell lines

In this study we have compared the interaction of human MHC class I molecules with IgG heavy chain (HC) binding protein (BiP), calnexin, calreticulin, tapasin and TAP in beta(2)-microglobulin (beta(2)m)- or TAP-deficient cells, as well as in wild-type B-LCL cells. Distinct differences between the association of HC and these endoplasmic reticulum (ER) proteins were found in the three cell lines. In

Post-tsunami recovery in Thailand : Socio-cultural responses

Of all the huge natural disasters that claimed the lives of thousands in Asia, the Indian Ocean tsunami in 2004 was the largest, estimated to have killed more than 230,000 people. The scope of damage brought about by this natural disaster urges focus on recovery and post-disaster reconstruction from several perspectives. Here we find an in-depth ethnography of Thailand and the role of culture and

Elevated Plasma Angiopoietin-2 Levels Are Associated With Fluid Overload, Organ Dysfunction, and Mortality in Human Septic Shock

OBJECTIVES: Angiopoietins modulate endothelial permeability via endothelial cell junctions. Angiopoietin-2 blocks the angiopoietin-1/Tie-2 interaction that stabilizes these junctions, and elevated plasma angiopoietin-2 levels are associated with vascular leakage. We hypothesized that plasma angiopoietin-1 and angiopoietin-2 levels are associated with indirect markers of increased vascular permeabi

A Method for Assessing Margin and Sensitivity of Electricity Networks With Respect to Repair System Resources

Modern society is becoming increasingly dependent on a continuous supply of electricity. In order to maintain the safety and security of society and its citizens, it is therefore necessary that electricity networks are resilient toward disruptions whether caused by natural disasters, sinister attacks, or other. Margin and sensitivity are two crucial aspects of the resilience concept which have so

Capturing Societal Interdependencies from a Flow perspective – Part II: Application

Societal functions constitute of public and private organisations and companies that provide commodities and services that are vi-tal for the functioning of the modern society. The public are highly dependent on these vital societal services and commodities, such as power supply, health care and education. In this paper we present an application of a method for collecting and structuring data and

Glaucoma follow-up when converting from long to short perimetric threshold tests

OBJECTIVES: To study the influence of test length in automated perimetry follow-up of glaucomatous eyes and, particularly, to determine if it is possible to usefully interpret test results obtained using a testing algorithm shorter than that used for baseline testing.METHODS: Automated perimetry findings were retrospectively evaluated in 31 patients with glaucoma for whom multiple Humphrey 30-2 te

Myocardial morphology and cardiac function in rats with renal failure

The effects of chronic renal failure on cardiac performance and myocardial morphology were studied in rats: 17 with 5/6 nephrectomy (CRF rats) and 12 with sham operation (controls). Cardiac function was assessed 8 weeks postoperatively, using the Langendorff technique for an isolated working heart model. After the hemodynamic study the hearts were fixed for electron and light microscopy. In the CR

Effect of erythropoietin treatment on physical exercise capacity and on renal function in predialytic uremic patients

Anemia is already present in patients with moderate renal failure and is a major cause of the decline in exercise capacity seen in these patients. We examined the effects of erythropoietin (EPO) treatment in 12 predialytic uremic patients (EPO group: mean age 46 ± 12 years; 6 men, 6 women) with a mean glomerular filtration rate (GFR) of 10 ± 4 ml/min x 1.73 m2. These patients were compared to a co