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Timing and type of breast reconstruction in SweBRO 3 : long-term outcomes

Background: Breast reconstruction after mastectomy helps women with breast cancer feel better about their bodies and lives. There is debate about the best time and type of reconstruction (immediate versus delayed, and using own tissue versus implants). Long-term studies are rare. Aim: This study looked at long-term results of different breast reconstruction methods and timings in Swedish women who

Idrottsbiografin bortom hjältemyten

After being considered a historiographical relic in the 1960s and 1970s, there have been several recent attempts to revitalise the scientific importance of the biography genre. The results have been partially successful, still biography as a genre still faces some methodological problems. In this article, I discuss the possibilities and pitfalls of the biography genre, based on personal research e

Cryogenic temperatures promote the pressure-induced polymorphic transition in CoCrFeMnNi high entropy alloy

Pressure-induced polymorphism has recently been demonstrated in several high entropy alloys. This offers a new window into the much-debated issue of phase selection and stability in these systems. Here, we examine the effect of cryogenic temperatures on the pressure-induced transition from face centered cubic to hexagonal close-packed structures of the prototype CoCrFeMnNi (Cantor) alloy. We obser

Upscaling cargo bike sharing in cities : A comparative case study

Urban mobility transitions are essential to mitigate climate change and improve the quality of life in cities. Cargo bikes (CBs) show promise in replacing motorised vehicles due to their lower carbon intensity, space efficiency, and ability to reduce air and noise pollution. CB sharing relieves users from purchase and maintenance costs. However, it is mainly adopted by individuals with high enviro

Change in different classes of chronic back pain suspicious of axial spondyloarthritis : A latent transition analysis of the SPACE cohort

Objectives To follow up four previously identified classes 'pure axial spondyloarthritis' (axSpA) ('axial'), 'axSpA with peripheral signs' ('inflammatory back pain+peripheral'), 'axSpA at risk' and 'no spondyloarthritis' ('no SpA'). They reflect the expert-opinion-free construct or 'Gestalt' of chronic back pain suspicious of axSpA. The aim was to assess participants' transitions between these cla

A missense mutation in the barley Xan-h gene encoding the Mg-chelatase subunit I leads to a viable pale green line with reduced daily transpiration rate

Key message: The barley mutant xan-h.chli-1 shows phenotypic features, such as reduced leaf chlorophyll content and daily transpiration rate, typical of wild barley accessions and landraces adapted to arid climatic conditions. Abstract: The pale green trait, i.e. reduced chlorophyll content, has been shown to increase the efficiency of photosynthesis and biomass accumulation when photosynthetic mi

Best practices in robotic magnetic navigation-guided catheter ablation of cardiac arrhythmias, a position paper of the Society for Cardiac Robotic Navigation

Preamble: Robotic magnetic navigation (RMN)-guided catheter ablation (CA) technology has been used for the treatment of cardiac arrhythmias for almost 20 years. Various studies reported that RMN allows for high catheter stability, improved lesion formation and a superior safety profile. So far, no guidelines or recommendations on RMN-guided CA have been published. Purpose: The aim of this consensu

Characterization of somatic mutations in sporadic uveal melanoma and uveal melanoma in patients with germline BAP1 pathogenic variants

Genetic analyses were conducted on tumor samples from 88 patients with uveal melanoma (UM), 6 of whom carry pathogenic germline variants in BAP1. We assessed the frequency, pattern, and prognostic significance of somatic aberrations, and investigated differences between germline BAP1 variant carriers compared to sporadic cases. The frequency of the main oncogenic driver mutations was not significa

Sherpas and Sagarmatha : complexity theory, ‘Edge of Chaos’ and implications for tourism risk management

Sagarmatha (Everest) has long been recognised as one of the principal goals of global adventure tourism. Supported by high-altitude workers, paying climbers on Sagarmatha have the opportunity to tread in the footsteps of colonial pioneers such as George Mallory and Sir Edmund Hillary. Ever since the first attempt was made to summit Sagarmatha there has been an appreciation amongst the climbing com

Preparation and Utilization of a Highly Discriminative Absorbent Imprinted with Fetal Hemoglobin

Development in hemoglobin-based oxygen carriers (HBOCs) that may be used as alternatives to donated blood requires an extensive supply of highly pure hemoglobin (Hb) preparations. Therefore, it is essential to fabricate inexpensive, stable and highly selective absorbents for Hb purification. Molecular imprinting is an attractive technology for preparing such materials for targeted molecular recogn

Reaction mechanism of pyridine radicals with molecular oxygen : A theoretical study

Pyridine is a suitable surrogate of the fuel-nitrogen in flame studies. The goal of the present work was to extend the analysis of reactions of pyridyl radicals with O2. All reactions proceed following similar mechanisms, through the barrier-free addition of an O2 molecule and further development along two main paths: through barrier-free abstraction of an oxygen atom and through the formation of

Spatial–Temporal Assessment of Eco-Environment Quality with a New Comprehensive Remote Sensing Ecological Index (CRSEI) Based on Quaternion Copula Function

The traditional remote sensing ecological index (RSEI), based on principal component analysis (PCA) to integrate four evaluation indexes: greenness (NDVI), humidity (WET), dryness (NDBSI), and heat (LST), is insufficient to comprehensively consider the influence of each eco-environment evaluation index on eco-environment quality (EEQ). In this research, a new comprehensive remote sensing ecologica

An extreme thermal cycling reliability test of ATLAS ITk Strips barrel modules

At the end of Run 3 of the Large Hadron Collider (LHC), the accelerator complex will be upgraded to the High-Luminosity LHC (HL-LHC) in order to increase the total amount of data provided to its experiments. To cope with the increased rates of data, radiation, and pileup, the ATLAS detector will undergo a substantial upgrade, including a replacement of the Inner Detector with a future Inner Tracke

Evidence for an active ice margin during the last deglaciation : the Vimmerby Moraine, South Swedish Uplands

The Vimmerby Moraine is the only significant ice-marginal moraine on the eastern side of southern Sweden, but no detailed studies exist on its formation during the final deglaciation of the Fennoscandian Ice Sheet. Through ground-penetrating radar surveys and detailed sediment logging, we provide evidence for an active, oscillating ice margin during the formation of the Vimmerby Moraine, suggestin