Importance: CD11b + immune cells have been implicated in the formation of choroidal neovascularization in experimental studies on animals and disease-association studies on humans. However, the clinical importance of such observations remains unknown. Objective: To investigate whether the proportion of CD11b + circulating monocytes is associated with the number of anti-vascular endothelial grow

BACKGROUND: Sacroiliac joint pain is increasingly recognized as a cause of low back pain. We compared the safety and effectiveness of minimally invasive sacroiliac joint arthrodesis using triangular titanium implants and conservative management in patients with chronic sacroiliac joint pain. METHODS: This study was a prospective, multicenter randomized controlled trial of adults with chronic sacro

Purpose: Functional outcomes vary between centers after out-of-hospital cardiac arrest (OHCA) and are partially explained by pre-existing health status and arrest characteristics, while the effects of in-hospital treatments on functional outcome are less understood. We examined variation in functional outcomes by center after adjusting for patient- and arrest-specific characteristics and evaluated

Objectives: Several studies have shown mortality and suicide risk in substance use disorders, and autopsy findings with respect to the used substances. However, there seems to be a gap in the knowledge about substances misused in life and at death at the within-person level. Methods: All consecutive, autopsied patients during 1993 to 1997, who had been in contact with the Addiction Centre in Malmö

We theoretically investigate transport signatures of quantum interference in highly symmetric double quantum dots in a parallel geometry and demonstrate that extremely weak symmetry-breaking effects can have a dramatic influence on the current. Our calculations are based on a master equation in which quantum interference enters as nondiagonal elements of the density matrix of the double quantum do

The calculated electronic band structure of graphene is relatively simple, with a Fermi surface consisting only of six Dirac cones in the first Brillouin zone - one at each K̄. In contrast, angle-resolved photoemission measurements of graphene grown on SiC(0001) often show six satellite Dirac cones surrounding each primary Dirac cone. Recent studies have reported two further Dirac cones along the

The "terminal investment" hypothesis proposes that individuals with low future survival prospects will gain from increasing investment in the current reproductive event even though it will reduce the chances of future reproduction even further. Such investments have previously been found to occur mainly during the late stages of the breeding event, that is, encompassing a short period of elevated

Sweden is often cited as one of the starkest examples of a country where corporatist policy structures and centralized wage bargaining produced remarkable economic and social outcomes in the postwar golden years. Not surprisingly, previous explanations for Sweden’s full employment period have emphasized this set of labor market institutions which was in place from the 1950s. Alternatively, tempora

Machine learning is a powerful technique, becoming increasingly popular in astrophysics. In this paper, we apply machine learning to more than a thousand globular cluster (GC) models simulated with the mocca-Survey Database I project in order to correlate present-day observable properties with the presence of a subsystem of stellar mass black holes (BHs). The machine learning model is then applied

We consider Bayesian inference for stochastic differential equation mixed effectsmodels (SDEMEMs) exemplifying tumour response to treatment and regrowth in mice. We produce an extensive study on how an SDEMEM can be fitted by using both exact inference based on pseudo-marginal Markov chain Monte Carlo sampling and approximate inference via Bayesian synthetic likelihood (BSL). We investigate a two-

Rheumatologists and general practitioners as a rule do not examine the nails when giant cell arteritis (GCA) is suspected, and may thus miss a simple yet valuable clinical sign. Splinter hemorrhage (SH) is a non-specific but significant clinical finding that can be seen in a wide range of conditions and by different medical specialists, among others: rheumatologists, infectious diseases specialist

When the Soviet Union invaded Hungary in 1956, a wave of streetlevel anti-communist protests swept overWestern Europe. These often violent protest were directed against Soviet embassies, domestic communist parties and communistnewspapers. The wave also reached Scandinavia, where the 1950’s otherwise is considered a calm and peaceful period. In Denmark and Sweden, a number of antiSoviet and anti-co

The aim of the present study is to examine and describe Swedish upper secondary students’ use of their background languages while translating a text from Italian, a language unknown to them, into either their L2 English or their L3 French or Spanish. The assumption here is that searching for similarities between these languages is a natural feature of language learning and that intercomprehension

Grundbok om kvalitativa och kvantitativa forskningsmetoder inom företagsekonomi och annan samhällsvetenskap.

Accurate histological classification and identification of fusion genes represent two cornerstones of clinical diagnostics in non-small cell lung cancer (NSCLC). Here, we present a NanoString gene expression platform and a novel platform-independent, single sample predictor (SSP) of NSCLC histology for combined, simultaneous, histological classification and fusion gene detection in minimal formali

Intern kommunikation är ett område som oftast har negligerats bland såväl forskare som praktiker. Merparten av forskningen och praktiken inom kriskommunikation har fokuserats på extern kommunikation vilket kan förklaras med att de flesta forskare inom fältet har sin bakgrund inom public relations och att den externa kommunikationen många gånger är mer tydlig för praktikerna. Men att intern kriskom

Metastatic melanoma is one of the most common deadly cancers, and robust biomarkers are still needed, e.g. to predict survival and treatment efficiency. Here, protein expression analysis of one hundred eleven melanoma lymph node metastases using high resolution mass spectrometry is coupled with in-depth histopathology analysis, clinical data and genomics profiles. This broad view of protein expres