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CYP1A2 plays a key role in the metabolism of both estrogen and coffee. Women with higher coffee intake and the CYP1A2*1F A/A genotype have a ratio of high 2-hydroxyestrone (2-OHE1) to 16alpha-OHE1. 2-OHE1 is a weak estrogen and may even block the estrogen receptor (ER), whereas 16alpha-OHE1 is procarcinogenic. We hypothesized that moderate to high coffee consumption (>/=2 cups per day) combined wi

The argument in this paper is that Hobbes’ theory of freedom in Leviathan allows for four ways of being free to act – corporal freedom by nature, freedom from obligation by nature, the freedom to disobey, and the freedom of no-rule – each corresponding to a particular absence, some of which make sense only in the civil state. Contrary to what some have claimed, this complexity does not commit Hobb

Widespread tree species must show physiological and structural plasticity to deal with contrasting water balance conditions. To investigate these plasticity mechanisms, a meta-analysis of Pinus sylvestris L. sap flow and its response to environmental variables was conducted using datasets from across its whole geographical range. For each site, a Jarvis-type, multiplicative model was used to fit t

BACKGROUND: Sarcoidosis has been reported to be associated with an increased risk of cancer; however, little information is available about the prognosis for sarcoidosis patients diagnosed with cancer. PATIENTS AND METHODS: A population-based cohort of sarcoidosis patients was identified from Swedish registers. Cause-specific and overall hazard ratios (HRs) were estimated by using Cox regression m

Protein E (PE) of nontypeable Haemophilus influenzae (NTHi) is involved in adhesion and activation of epithelial cells. A total of 186 clinical NTHi isolates, encapsulated H. influenzae, and culture collection strains were analyzed. PE was highly conserved in both NTHi and encapsulated H. influenzae (96.9%-100% identity without the signal peptide). PE also existed in other members of the genus Pas

Artificial neural networks (ANNs) is a nonlinear pattern recognition technique inspired by the function of the human brain. ANNs have been used successfully in analysis of complex medical relationships, for example prognostic predictions of various forms of cancer. Acute pancreatitis and pancreatic cancer are commonly recognized to be extremely difficult conditions in making diagnostic and prognos

The main objective of this investigation is to determine the effect of different physical parameters on the performance of biofilters, treating hydrophobic compounds. In this respect, the effects of irrigation and water content of packings on the removal efficiency of bed in different pollutant loading rates, and gas phase flow rates, is studied. Alpha-pinene, which is produced from variety of ind

This research report has two objectives, both focusing on the supply chain flows passing or crossing the Öresund maritime area. The first objective is to identify and describe the flows in Öresund and the risks for disturbances in those flows before and after the opening of the Öresund Link in July 2000. With the opening of the Öresund Link a new goods and passenger flow was created. As a resul

All 74 patients treated with vena cava filter insertion during 1991-2000 at Malmo University Hospital were reviewed. Thirty-nine patients (53%) died during follow-up. Indications for permanent filter insertion (n = 63, age 25-89 years, 35 men) were contraindication for or side effects of anticoagulant treatment, or pulmonary embolism during anticoagulant treatment. Temporary vena cava filters (n =

The crypt in Dalby as a batisterium – a digital reconstruction The article presents an example of the on-going research at Dalby in Scania, Sweden, focusing on the baptismal font and its original medieval context. The site and the current research are presented. Dalby was a medieval cathedral, Augustinian monastery and maybe also a royal manor. The crypt and font from the 12th C are presented. Th

Continuing on the topic presented in the last number of Ancient Planet Online (2012/2), which introduced the topic of pseudo script in the ancient quarries at Gebel el Silsila in Egypt, this article will look closer at one group of quarry marks and their symbolic association with solar religion during the Ptolemaic and early Roman periods.