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Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease

CD4+ T cells subsets have a wide range of important helper and regulatory functions in the immune system. Several studies have specifically suggested that circulating effector CD4+ T cells may play a direct role in control of HIV replication through cytolytic activity or autocrine β-chemokine production. However, it remains unclear whether effector CD4+ T cells expressing cytolytic molecules and β

A 1.8Gb/s 70.6pJ/b 128×16 link-adaptive near-optimal massive MIMO detector in 28nm UTBB-FDSOI

This work presents a 2.0mm2 128×16 massive MIMO detector IC that provides 21dB array gain and 16x multiplexing gain at the system level. The detector implements iterative expectation-propagation detection (EPD) for up to 256-QAM modulation. Tested with measured channel data [1], the detector achieves 4.3dB processing gain over state-of-the-art massive MlMo detectors [2, 3], enabling 2.7x reduction

The Genetics of Urinary Tract Infections and the Innate Defense of the Kidney and Urinary tract

The urinary tract is a sterile organ system. Urinary tract infections (UTIs) are common and often serious infections. Research has focused on uropathogen, environment, and host factors leading to UTI pathogenesis. A growing body of evidence exists implicating genetic factors that can contribute to UTI risks. In this review, we highlight genetic variations in aspects of the innate immune system cri

Consumer motivations for sustainable consumption : The interaction of gain, normative and hedonic motivations on electric vehicle adoption

Recent conceptual studies identify gain, normative and hedonic factors as three categories of motivations of consumer proenvironmental behavior. However, empirical understanding of how these motivations interact and affect proenvironmental behavior is limited. This study is based on a survey of car owners in Sweden (N = 573) and uses structural equation modeling to analyze the data. The empirical

Socioeconomic aspects of unmet healthcare needs and health outcomes - Economic conditions, social capital, unmet healthcare needs, healthcare providers and mortality

Socioeconomic status (SES) differences in health are well known. Both material and psychosocial hypotheses regarding these SES differences have been forwarded. Social capital (trust, social participation) may be seen as a contextual and social extension of this debate with access to healthcare as one of the four hypothesized mechanisms between high social capital and health. This thesis investigatSocioeconomic status (SES) differences in health are well known. Both material and psychosocial hypotheses regarding these SES differences have been forwarded. Social capital (trust, social participation) may be seen as a contextual and social extension of this debate with access to healthcare as one of the four hypothesized mechanisms between high social capital and health. This thesis investigat

Basic modelling of transport in 2D wave-mechanical nanodots and billiards with balanced gain and loss mediated by complex potentials

Non-Hermitian quantum mechanics with parity-time (PT) symmetry is presently gaining great interest, especially within the fields of photonics and optics. Here, we give a brief overview of low-dimensional semiconductor nanodevices using the example of a quantum dot with input and output leads, which are mimicked by imaginary potentials for gain and loss, and how wave functions, particle flow, coale

Thermoelectric Power Factor Limit of a 1D Nanowire

In the past decade, there has been significant interest in the potentially advantageous thermoelectric properties of one-dimensional (1D) nanowires, but it has been challenging to find high thermoelectric power factors based on 1D effects in practice. Here we point out that there is an upper limit to the thermoelectric power factor of nonballistic 1D nanowires, as a consequence of the recently est

Motion induced interplay effects for VMAT radiotherapy

The purpose of this study was to develop a method to simulate breathing motion induced interplay effects for volumetric modulated arc therapy (VMAT), to verify the proposed method with measurements, and to use the method to investigate how interplay effects vary with different patient- and machine specific parameters. VMAT treatment plans were created on a virtual phantom in a treatment planning s

Electrical and optical evaluation of n-type doping in InxGa(1-x)P nanowires

To harvest the benefits of III-V nanowires in optoelectronic devices, the development of ternary materials with controlled doping is needed. In this work, we performed a systematic study of n-type dopant incorporation in dense InxGa(1-x)P nanowire arrays using tetraethyl tin (TESn) and hydrogen sulfide (H2S) as dopant precursors. The morphology, crystal structure and material composition of the na

Learning with and from each other : promoting international and interprofessional collaborations in physiotherapy education research – a literature review

Background: Best practice in physical therapy education requires good quality and quantity of research based on authentic learning settings and teaching practices. Facilitating large multisite research and large data sets for analysis has the potential to contribute to a strong research base. Clinical research makes use of international and interprofessional consortiums to produce quantity and qua

Rituals of global health : Negotiating the World Health Assembly

The World Health Assembly is the WHO’s supreme decision-making body and consists of representatives from the 194 WHO Member States who take formal decisions on the WHO’s policies, workplan and budget. The event is also attended by representatives of non-governmental organisations, the private sector, the press and even members of the public. Based on participant observation at six World Health Ass

Submerged Landscapes in the Hanö Bay : Early Holocene shoreline displacement and human environments in the southern Baltic Basin

Under istider, när stora mängder havsvatten var bundet i inlandsisar, var den globala havsnivån lägre än idag och stora delar av kontinentalsockeln torrlagd. Den senaste istiden (cirka 115 000–12 000 år sedan) var inget undantag, då torrlagda områden utvecklades till ekologiskt rika kustområden som möjliggjorde människans spridning över världen. När inlandsisarna smältesteg havsnivån och dessa lanDuring times of lower global sea level, vast areas of the coastal shelf were exposed and converted into ecologically diverse coastal landscapes that wereattractive for human occupation. The landscapes were subsequently flooded during the deglaciation, but well-preserved remains of these landscapes andtheir inhabitants can today be found on the seafloor. In the southern Baltic Basin, where the comp