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The built environment accounts for approximately 32 % of the global final energy use but also holds great potential for energy efficiency still to be harnessed (Lucon et al., 2014). To develop innovative policies for energy efficiency that are capable of realizing transformative changes, we argue that there is an urgent need for new systemic evaluation frameworks that provide learning and knowledg
Whole-genome sequencing (WGS) brings comprehensive insights to cancer genome interpretation. To explore the clinical value of WGS, we sequenced 254 triple-negative breast cancers (TNBCs) for which associated treatment and outcome data were collected between 2010 and 2015 via the population-based Sweden Cancerome Analysis Network-Breast (SCAN-B) project (ClinicalTrials.gov ID:NCT02306096). Applying
Semiconductor nanostructure based devices provide new opportunities for contributing to a sustainable energy usage. This includes harvesting of energy (solar cells) and saving of energy, e.g. in lighting (light-emitting diodes, LEDs) and transfer of energy (power devices). However, development and improvement of nanostructure devices requires thorough characterization and understanding on a singleSemiconductor nanostructure based devices provide new opportunities for contributing to a sustainable energy usage. This includes harvesting of energy (solar cells) and saving of energy, e.g. in lighting (light-emitting diodes, LEDs) and transfer of energy (power devices). However, development and improvement of nanostructure devices requires thorough characterization and understanding on a single
The divide between interest groups and social movement studies runs deep, but present developments call for a renewed focus on the relevance of these analytical categories. Both of these two forms of collective action relate to organisations that are assumed to follow distinctive logics and strategies for political influence. This article aims to contribute to the debates on the analytical differe
OBJECTIVES: An extended-wavelength diffuse reflectance spectroscopy (EWDRS) technique was evaluated for its ability to differentiate between and classify different skin and tissue types in an in vivo pig model.MATERIALS AND METHODS: EWDRS recordings (450-1550 nm) were made on skin with different degrees of pigmentation as well as on the pig snout and tongue. The recordings were used to train a sup
In last couple of decades the field of glycobiology has developed rapidly due to the increased understanding of glycans’ abilities to encode biological information, which may have impact on biological event and disease, such as for example tumour growth and inflammation. This development has been accompanied by an increasing focus on drug discovery revolving around a category of carbohydrate-based
Denna rapport har tagits fram inom forskningsprogrammet Mistra Sustainable Consumption – från nisch till mainstream som engagerar forskare från olika vetenskapliga discipliner och samhällspartners från offentlig sektor, näringsliv och civilsamhälle. Syftet med programmet är att stimulera en övergång till mer hållbar konsumtion. Forskningen är finansierad av Mistra, Stiftelsen för miljöstrategisk f
Bertolt Brecht (1898–1956) är en av 1900-talets stora teaterförnyare genom sitt radikala ifrågasättande av konstens relation till samhället och till skådespelarens gestaltningstradition. I den samtida teaterdiskussionen är hans historiska och politiska överblick oumbärlig och i denna essäsamling prövas styrkan i hans argument i relation till några samtida och historiska konstnärliga frågor av högs
This chapter contributes to literature on sustainable innovation by critically engaging with the concept of sustainable innovation in business models. Four types of models purported to contribute to sustainability are explored: circular business models, product–service systems, business models for collaborative consumption, and business models for collaborative production. First, we evaluate each
According to some accounts, an individual participates in joint intentional cooperative action by virtue of conceiving of him- or herself and other participants as if they were parts of a single agent or body that performs the action. I argue that this notional singularization move fails if they act as if they were parts of a single agent. It can succeed, however, if the participants act as if to
PURPOSE: Nucleophosmin 1 (NPM1) mutations are associated with a favorable prognosis in acute myeloid leukemia (AML) when an internal tandem duplication (ITD) in the fms-related tyrosine kinase 3 gene (FLT3) is absent (FLT3-ITDneg) or present with a low allelic ratio (FLT3-ITDlow). The 2017 European LeukemiaNet guidelines assume this is true regardless of accompanying cytogenetic abnormalities. We
Site-specific land management practice taking into account variability in maize yield gaps (the difference between yields in the 90th percentiles and other yields on smallholder farmers’ fields) could improve resource use efficiency and enhance yields. However, the applicability of the practice is constrained by inability to identify patterns of resource utilization to target application of resour
Whether cyclodextrins (CDs) self-aggregate or not in solution is an interesting and timely scientific question. Yet, we are far from a scientific consensus as regards the nature of the phenomenon. Those who are in favor of the formation of CD aggregates justify the phenomenon by the presence of H-bonds, occurring between the hydroxyl groups located at both rims of cyclodextrins. To gain further in
Weakly-coupled TeV-scale particles may mediate the interactions between normal matter and dark matter. If so, the LHC would produce dark matter through these mediators, leading to the familiar “mono-X” search signatures, but the mediators would also produce signals without missing momentum via the same vertices involved in their production. This document from the LHC Dark Matter Working Group sugg
The International Association of Fire Safety Science (IAFSS) is comprised of members from some 40 countries. This paper presents the Association's thinking, developed by the Management Committee, concerning pressing research needs for the coming 10 years presented as the IAFSS Agenda 2030 for a Fire Safe World. The research needs are couched in terms of two broad Societal Grand Challenges: (1) cli
