Fever control interventions versus placebo, sham or no intervention in adults : a protocol for a systematic review with meta-analysis and Trial Sequential Analysis
Introduction Fever is an integral part of the inflammatory response and has therefore likely a physiological role in fighting infections. Nevertheless, whether fever in itself is beneficial or harmful in adults is unknown. This protocol for a systematic review aims at identifying the beneficial and harmful effects of fever control interventions in adults. Methods and analysis This protocol for a s