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European Stroke Organisation (ESO) standard operating procedure for the preparation and publishing of guidelines

The first European Stroke Organization (ESO) standard operating procedure (SOP) published in 2015 aimed at the implementation the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology to provide evidence-based guidelines for stroke management. This second ESO-SOP is aiming at further increase of the practicability of ESO guidelines and its technical implications. A

The value of human data annotation for machine learning based anomaly detection in environmental systems

Anomaly detection is the process of identifying unexpected data samples in datasets. Automated anomaly detection is either performed using supervised machine learning models, which require a labelled dataset for their calibration, or unsupervised models, which do not require labels. While academic research has produced a vast array of tools and machine learning models for automated anomaly detecti

Population heterogeneity in associations between hormonal contraception and antidepressant use in Sweden : a prospective cohort study applying intersectional multilevel analysis of individual heterogeneity and discriminatory accuracy (MAIHDA)

OBJECTIVES: From a reproductive justice framework, we aimed to investigate how a possible association between hormonal contraceptive (HC) and antidepressants use (as a proxy for depression) is distributed across intersectional strata in the population. We aimed to visualise how intersecting power dynamics may operate in combination with HC use to increase or decrease subsequent use of antidepressa

Concepts as Tools of Legal Reasoning – How Pragmatics May Promote the Rationality of International Legal Discourse and the Work of Legal Scholars

Concepts are an important element of the way international lawyers think and talk about international law. They materialise as conceptual terms, such as ‘jurisdiction’, ‘self-defence’ and ‘abuse of rights’. To enable a critical evaluation of international law and legal discourse, it is important that single instances of use of such terms be fully understood. This task presupposes a full recognitioConcepts are an important element of the way international lawyers think and talk about international law. They materialise as conceptual terms, such as ‘jurisdiction’, ‘self-defence’ and ‘abuse of rights’. To enable a critical evaluation of international law and legal discourse, it is important that single instances of use of such terms be fully understood. This task presupposes a full recognitio

A noise related track maintenance tool for severe wear detection of wheel-rail contact

An on-board measurement system has been developed that in real time identifies the probability for occurrence and also the exact location of severe wear in the wheelrail contact. Noise generated by the wheel-rail contact is a troublesome side effect both when railway vehicles negotiate curves and run on straight tracks. The concept behind this project is to use this noise as an indicator of the tr

The effect of Subzero temperature and snow on the tribology of wheel-rail contact

The wheel-rail system operates in an open environment where the weather condition varies constantly. In this laboratory study, an investigation using a pin-on-disc tribometer placed in a temperature-controlled room was conducted to examine the effect of subzero temperature and snow on friction and wear at the wheel-rail contact. In temperature range from 3 to-15 °C (without snow) friction and wear

Preventing Cardiovascular Disease. Complementary precision medicine.

AbstractBackground: Non-communicable diseases are the number one killer worldwide and the leading one,cardiovascular disease (CVD), is responsible for more than 30% of all deaths. CVD is a progressive disease whichalso makes it economical, easy and effective to prevent. There are many stages of CVD that ultimately can lead tocoronary atherosclerosis, measurable as coronary artery calcification (CA

Profetian är primärt inte för de otrogna : En argumentationsanalys av 1 Kor 14:22b

Traditional analyses of 1 Cor 14:20–25 have not been able to solve the interpretational problems, especially the crux interpretum of v. 22b. Since the problem is one of argumentation it is natural to seek assistance from a method of argumentation analysis. By making use of the method by Stephen Toulmin, it can be shown that the argument may contain more information than is directly apparent. By re

Paulus argumentation i Galaterbrevet 3:6–14

Gal 3:6–14 är ett av många avsnitt i Paulus brev som är svårt att förstå p.g.a. den komplicerade argumentationen. En argumentationsanalys är därför påkallad för att reda ut argumenten och för att klargöra eventuella implicita premisser. En sådan analys ger oss en bättre uppfattning av Paulus argumentation än en traditionell exeges ensam kan ge. Analysen ger vid handen att Paulus försöker övertyga

The Gospel of Matthew as a Literary Argument

Through an argumentation analysis can one show how it is feasible to view a narrative religious text such as the Gospel of Matthew as a literary argument. The Gospel is not just “good news” but an elaborate argument for the standpoint that Jesus is the Son of God, the Messiah. It is shown why an argumentation analysis needs to be supplemented with a pragmatic literary analysis in order to describeThrough an argumentation analysis can one show how it is feasible to view a narrative religious text such as the Gospel of Matthew as a literary argument. The Gospel is not just “good news” but an elaborate argument for the standpoint that Jesus is the Son of God, the Messiah. It is shown why an argumentation analysis needs to be supplemented with a pragmatic literary analysis in order to describe

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The article analyses techniques of verbal rhetoric based on recordings of prayer meetings from the first year of the Nokia Missio Church (2008–2009). The rhetorical situation is of particular interest in this charismatic congregation. The crowd can be examined from the viewpoint of the various participant groups, drawing on Lloyd Bitzer’s idea of the life span of a rhetorical situation. Classical

A systematic literature review of user interaction with energy-efficient solutions in indoor environment

Even though the design of buildings and technologies have been mainly focused on reducing energy use, there is still a discrepancy between predicted and actual energy saving due to user behavior. There is a need of understanding the behavior and relevant factors of using energy-efficient solutions. Energy-efficient solutions in an indoor environment can be defined as building characteristics such

Genetically targeted clinical trials in parkinson’s disease : Learning from the successes made in oncology

Clinical trials in neurodegenerative disorders have been associated with high rate of failures, while in oncology, the implementation of precision medicine and focus on genetically defined subtypes of disease and targets for drug development have seen an unprecedented success. With more than 20 genes associated with Parkinson’s disease (PD), most of which are highly penetrant and often cause early

Large exchange bias in Cr substituted Fe3O4nanoparticles with FeO subdomains

Tuning the anisotropy through exchange bias in bimagnetic nanoparticles is an active research strategy for enhancing and tailoring the magnetic properties for a wide range of applications. Here we present a structural and magnetic characterization of unique FeCr-oxide nanoparticles generated from seed material with a Fe : Cr ratio of 4.71 : 1 using a physical aerosol method based on spark ablation