Filetype
Är åldersspecifika olikheter på proteinnivå nyckeln till nya behandlingar? Behovet av nya behandlingsmetoder för leukemi är ett faktum. I denna studien har vi undersökt leukemiceller från barn och vuxna på proteinnivå. Genom att identifiera åldersrelaterade olikheter kan dessa utnyttjas i framtida utveckling av behandlingar riktade mot särskilda varianter av leukemi för barn och vuxna. Leukemi
Avloppsreningsmetod för att rena dricksvatten Målet med dricksvattenrening är att bli av med oönskade ämnen i vattnet, så som sjukdomsframkallande bakterier och organiskt material. Detta säkerställer inte bara vattnets säkerhet utan också dess smak, lukt och utseende. Det finns flera olika metoder för att rena vatten, och vilken metod som används beror på vattnets kvalitet och ursprung, samt vilkAt the drinking water treatment plant (DWTP) at Ringsjöverket (Sweden, Stehag), where this project is executed, a process of rapid sand filter (RSF) and slow sand filter (SSF) is used as a part in treating surface water into drinking water. The Moving bed biofilm reactor (MBBR) is a simple and strong biological process that has been shown to be effective in treating polluted raw water from nitroge
Utvecklingen av digitala 3D stadsmodeller i städer har ökat de senaste åren där fokus mestadels varit på byggnader. I den här studien presenteras transportinfrastruktur med olika detaljnivåer (LoD). Det svenska verksamhetssystemet inom transport NVDB samt kommunala trafikdata länkas till en informationsmodell som heter 3CIM. Via digitaliserade ytor i form av trafikområden kopplas väglänks-ID fThe developement of digital 3D city models in cities has increased during recent years with focus on mostly buildings. In this study transport infrastructure is presented with different levels of detail (LoD). The Swedish transportationssystem NVDB and municipality trafficdata are linked to an informationmodel 3CIM. Through digitized trafficareas a road-link id is used to enrich areas with att
Detta examensarbete är en studie av mellanrum i urban miljö. Mellanrum finns överallt runt omkring oss, men de är rum de flesta av oss sällan tänker på. Genom studier i utvalda urbana områden och konstnärligt utforskande undersöker arbetet hur mellanrum kan definieras, deras betydelse för stadsmiljön och hur vi kan involvera dem i en arkitektonisk process. Projektet syftar till att öka förståelse
The buildings and construction sector plays a key role for the European Union to achieve its climate targets. Continuous failure of the sector ́s climate mitigation has brought up a rising discussion about the compatibility of infinite economic growth and long-term socio-ecological sustainability. Grounded in the concept of degrowth, this study analyzes the implicit sustainability understandings a
Amphibians are the most rapidly declining vertebrate class globally and are especially vulnerable to habitat fragmentation causing population isolation. The genetic consequences of population size reduction, inbreeding and genetic drift, can have detrimental effects on the long-term viability of amphibian species, often leading to extinction. Population genomics approaches have become a crucial to
Spatial transcriptomics, a powerful technique that merges sequencing and spatial data, offers unprecedented resolution for studying gene expression within tissues. This study focuses on developing a pipeline to design probes for Multiplexed Error-Robust Fluorescence In Situ Hybridisation (MERFISH) experiments to investigate the spatial distribution of the lung microbiome. Metagenomic data analysis
From Strands to Wires All the genetic information required to develop and maintain an organism is packed tightly into the molecule known as DNA. Determining the order of the four bases, which are the building blocks of DNA, enables the identification of a DNA segment. Modern disease diagnostics use this identification method, known as DNA sequencing, to inspect genetic integrity. Thus, it is vita
Spatial omics allows for the investigation of the Tumor Immune Microenvironment (TIME). Stratifying patients by their TIMEs contributes with insights on tumor immune escape, and help in tumor drug targeting. Tools to investigate such spatial omics approaches suffer from high costs and limited direct clinical applicability. We address this issue by proposing a Machine Learning model which learns to
The aim of this research project was to create a bioinformatic image analysis pipeline for the investigation of lymphocytes in healthy human lungs. The lung is an important organ to study as it provides a fast way for pathogens to enter the body. Therefore, the pulmonary immune system must be further investigated in both healthy and diseased tissue. In order to do comparative studies, we need to c
En fungerande stadsbyggnad och översvämningriskhantering i Quezon City, Filippinerna, ett snabbt växande område med omfattande utbredning av informella bosättningar, är avgörande med tanke på den omfattande risken för översvämningar. Detta examensarbete syftar till att bidra till strategier för stadsplanering i översvämningsdrabbade områden genom att integrera en maskininlärningsmodell med stadsbyUrban development and flood risk management in Quezon City, Philippines, a rapidly urbanising area with extensive informal settlements, are critical given the city's vulnerability to flooding. This thesis aims to contribute to the theoretical framework for urban development in flood-prone areas by integrating a machine-learning model with contextual urban planning. The model uses a Random Fore
This thesis explores reasons of the marginalization of Scanian landscape paintings in the Swedish art history between 1885–1915. The first research question will investigate the construction of the narrative of Swedish art history and how it correlates to the perceived image of Sweden at the turn of the century. The second question examines the consequences this has had for the perception of the S
Peptidläkemedel måste ofta tas som injektioner eftesom peptider är för stora för att kunna absorberas genom celler den orala rutten. Men genom att inkludera absorbtionsförbättrare (surfaktanter) så kan denna absorbtionen för bättras, vilket skulle kunna möjliggöra skapandet av peptidläkemedel i tablettform! Genom att studera interaktionerna mellan peptider och absorbtionsförbättrare så kan man få Therapeutic peptides can often not be formulated as tablets by themselves as they’re prone to enzyme degradation the oral route - they also do not present good enough passage through epithelial cells to be viable for this dosage form. But if formulated together with surfactants, e.g., sodium caprate (C10), the absorption through epithelial cells can be increased. When peptides and absorption enhan
For banks to remain resilient in times of economic instability, and what the Chair of the Supervisory Board of the European Central Bank refers to as; “radical uncertainty”, it is essential for banks to plan for the future. Challenges such as rising interest rates, climate change and geopolitical conflicts require proactive measures. Thus, accurately predicting bank revenue plays a crucial role in
This thesis work was carried out for Höganäs AB, the world leading metal powder manufacturer. The goal was to create a program that automatically compiled logged data from their heat treat ing ovens and present it graphically, based on input in the form of time intervals. The program should also be able to compare outcomes during different time intervals and outcomes in different assignments. Due
I have explored methods of rehearsing pieces in order to play them by heart. I chose to do this study as I wanted to explore if I become more present during my performances if I play by heart. I have read about several methods and tried the ones I found relevant to me which included practice with and without instruments. My choices of methods were visualization, rotating practice schedule and chun
Brasilia, Brazil’s capital, is a city designed under the modernist precepts of the 60s. Its urbanistic plan is defined in four urban scales. Each of these occupies a different location in the city and has its own characteristics, which will be explored in this work. Especially the scale of the city center, which will be the focus of this project. Regional and local analyses were key to understand
The purpose of this study is to give an insight into the archival management of six student nations at Lund University, as well as the general view of the archive amongst the members who are responsible for the student nation archives. The majority of the student nations are well over 300 years old, but there have been few or no studies about the student nations archives, a knowledge gap this stud
With the increasing demands for higher data rates and long-range wireless power transfer, the development of new methods is a necessary step to meet the heightened requirements. One such method is improving the infrastructure for wireless transmission through the use of large intelligent surfaces (LIS). To be one step closer to enabling the construction of such infrastructure, this study examines
The overarching purpose of this thesis was to explore one aspect of Chinese foreign policy known as ‘wolf warrior diplomacy’: a rhetorical and polemic tool wielded by Chinese diplomats to deflect and counter criticism commonly perceived as hostile. This (un)diplomatic approach has bewildered many, which precipitates questions of its use and pertinence especially during a timeline in which China is
