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Hypothalamic and Neuroendocrine Changes in Huntington's Disease.

Huntington's disease (HD) is a fatal hereditary neurodegenerative disorder without satisfactory treatments nor a cure. It is caused by a CAG repeat expansion in the huntingtin gene. The clinical symptoms involve motor-, cognitive- and psychiatric disturbances. Recent studies have shown that non-motor symptoms and signs, such as mood changes, sleep disturbances and metabolic alterations often occur

Köln E52 – Radioraritet med rörande varmt mottagande

Den kanske allra bästa radiomottagaren under andra världskriget heter Köln E52, figur 1, och konstruerades och byggdes av Telefunken. Den har med åren blivit en raritet eftersom kriget, tillsammans med tidens tand, reducerat antalet mottagare betydlig. Det var därför med stor glädje och förvåning som en sådan apparat nyligen återupptäcktes på Lunds Tekniska Högskola (LTH).

Get it Right, Now: Focus on building a successful VAR business

Although the challenges posed by convergence are many, incumbent security integrators and VARs who get it right have everything to gain. Although they might not be able to acquire the leading-edge capabilities of some of their IT competitors, the integrator’s firm grasp of all aspects of traditional security, their unique ability to integrate old with new technology, and perhaps most importantly,

Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, MSX1, Ngn2, and Pitx3.

Neurons derived from neural stem cells could potentially be used for cell therapy in neurodegenerative disorders, such as Parkinson's disease. To achieve controlled differentiation of neural stem cells, we expressed transcription factors involved in the development of midbrain dopaminergic neurons in rat and human neural progenitors. Using retroviral-mediated transgene delivery, we overexpressed L