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Diversity of CD1d-restricted natural killer T cells

Popular Abstract in Swedish Cellerna I vårt immunförsvar hjälper oss att eliminera olika typer av infektioner orsakade av parasiter, bakterier och virus. Ibland klarar dessa celler även av att ta bort tumörceller, kroppsegna celler som börjat att dela på sig okontrollerbart. Det måste betyda att cellerna i immunförsvaret kan se skillnad på kroppsegna celler och främmande celler och strukturer (antThe present study deals with natural killer (NK) T cells restricted to the antigen presenting molecule CD1d. NKT cells have been suggested to play a role in many diverse immunological situations such as clearance of different pathogens, protection against certain tumors, regulation of autoimmune reactions and as a link between innate and adaptive immune responses. NKT cells are in many respects un

Service stations along global knowledge pipelines - on innovation intermediaries' function in fostering globalized innovation processes

Innovation is an interactive learning process that is facilitated naturally by geographic proximity. Innovation intermediaries can serve as an extra catalyst to and facilitator of interaction and collaboration. With today’s more globalized knowledge and innovation landscape, companies and research organizations seek complementary competencies and partners with whom they can collaborate on a much b

Finding a heaviest triangle is not harder than matrix multiplication

We show that for any ε > 0, a maximum-weight triangle in an undirected graph with n vertices and real weights assigned to vertices can be found in time O(nω + n2+ε), where ω is the exponent of fastest matrix multiplication algorithm. By the currently best bound on ω, the running time of our algorithm is O(n2.376). Our algorithm substantially improves the previous time-bounds for this problem recen

An NADH-Coupled Biosensor for Engineering Redox Metabolism in Saccharomyces cerevisiae

Popular Abstract in English The work described in this thesis is in the field of industrial biotechnology, which can be defined as a branch of biotechnology aimed at sustainable production of chemicals, materials and fuels with the help of microorganisms. Microorganisms are very diverse and possess a wide variety of enzymes allowing them to transform inexpensive molecules into valuable ones, or toBaker’s yeast, Saccharomyces cerevisiae’s potential in industrial biotechnology for producing valuable products e.g. biofuels, bulk chemicals, bio-flavours and pharmaceuticals is established. In order to achieve efficient production, the intracellular balance of the NADH/NAD + redox couple must be monitored and maintained, as this influences the feasibility of over 100 reactions in the cell. My ap

Injectable calcium sulphate and calcium phosphate bone substitutes

Two formulations of biphasic injectable bone substitutes have been developed for the treatment of bone defects and stabilisation of fragility fractures. The first formulation consists of a calcium sulphate matrix with embedded hydroxyapatite (HA) particles to provide osteoconductivity. The mechanical properties of this formulation were investigated by focussing on the factors affecting the compre

Binarity of Hipparcos Main Sequence Survey Stars

Hipparcos observations of double stars, mainly A and F primaries, aremodelled in order to check the statistics of double-star solutions inthe Hipparcos Catalogue and to set quantitative limits on binarydistributions. The number of companions per primary is estimated to 0.25+/-0.05 for semi-major axes from 1 to 10 AU, and to 0.43 +/-0.20 for therange 10--100 AU. The total multiplicity found is betw

Counting Thin Subgraphs via Packings Faster Than Meet-in-the-Middle Time

Vassilevska and Williams (STOC 2009) showed how to count simple paths on k vertices and matchings on k/2 edges in an n-vertex graph in time n^{k/2+O(1)}. In the same year, two different algorithms with the same runtime were given by Koutis and Williams (ICALP 2009), and Björklund et al. (ESA 2009), via nst/2+O(1)-time algorithms for counting t-tuples of pairwise disjoint sets drawn from a given fa

Towards Bridging the Gap Between Dalvik Bytecode and Native Code During Static Analysis of Android Applications

We propose a method for statically analyzing components that can be part of Android applications and which have not been very well analyzed so far, namely native libraries. As of now, third-party native code can be seen as a black box that can be fed input parameters from the Dalvik bytecode context, and output parameters can be returned back to the bytecode context. However, the native code can s