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A comment on the physiological basis for longitudinal motion of the arterial wall

The longitudinal motion and the intramural shear strain of the arterial wall increase dramatically in response to blood pressure, thereby impacting the vascular wall microenvironment. Exposure to a sedentary lifestyle has been identified as an independent risk factor for cardiovascular disease, but it has been shown that intermittent physical activity embedded into everyday life is enough to impro

Laminarins and their derivatives affect dendritic cell activation and their crosstalk with T cells

This research explores the impact of structural variations in laminarins derived from seaweed on their immunomodulatory properties. Laminarins from Laminaria digitata, L. hyperborea, and Saccharina latissima, were obtained using a two-step water extraction protocol, followed by structural characterization by FT-IR spectroscopy, 1H NMR, and MALDI-TOF MS. The laminarin backbones were confirmed as β–

”Kraftringen har blivit en belastning för Lundaborna.”

Sveriges högsta elkostnader är resultatet av Kraftringens spretighet och dess historiskt höga benägenhet att investera i allsköns misslyckade projekt långt utanför Lunds kommungräns, skriver Lars Jonung, professor emeritus i nationalekonomi på Lunds universitet och Jan Rydenfelt, tidigare finansdirektör.

Did Grandmothers Enhance Reproductive Success in Historic Populations? : Testing Evolutionary Theories on Historical Demographic Data in Scandinavia and North America

Human reproductive success requires both producing children and making investments in the development of offspring. To a large extent these investments are made by the parents of the child, but researchers are now looking beyond the nuclear family to understand how extended kin, notably grandmothers, enhance reproductive success by making transfers to progeny of different kinds. The extent to whic

Institutional Complexity in World Politics

While the post-1945 period witnessed the rise of multilateralism and the creation of numerous international institutions to deal with cross-border issues, the 21st century is marked by their contestation and transformation. The United Nations, including its specialized agencies and several other bodies, has come under heavy criticism for the inability to effectively cope with global challenges. In

Immunological biomarkers in patients with radiographic axial spondyloarthritis, an exploratory longitudinal Swedish study

Objectives: There is a need for more specific biomarkers to diagnose and predict disease course in patients with axial spondyloarthritis (axSpA). This study aimed to study immunological plasma biomarkers at different time-points in radiographic (r)-axSpA patients overall and stratified by sex and compare these biomarker patterns in r-axSpA patients concerning disease phenotypes and disease activit

Treating shock with norepinephrine administered in midline catheters in an intermediary care unit : A retrospective cohort study

Objectives A rising incidence of septic shock as well as recommendations for early vasopressor initiation has increased the number of patients eligible for norepinephrine (NE). Traditionally, NE has been administered through central lines, in intensive care units, due to the risk of extravasation in peripheral lines. The aim of the current study is to determine the rate of complications and patien

GARCH-Informed Neural Networks for Volatility Prediction in Financial Markets

Volatility, which indicates the dispersion of returns, is a crucial measure of risk and is hence used extensively for pricing and discriminating between different financial investments. As a result, accurate volatility prediction receives extensive attention. The Generalized Autoregressive Conditional Heteroscedasticity (GARCH) model and its succeeding variants are well established models for stoc

Predicting troponin biomarker elevation from electrocardiograms using a deep neural network

Background Elevated troponin levels are a sensitive biomarker for cardiac injury. The quick and reliable prediction of troponin elevation for patients with chest pain from readily available ECGs may pose a valuable time-saving diagnostic tool during decision-making concerning this patient population. Methods and results The data used included 15 856 ECGs from patients presenting to the emergency r

Effectiveness of nutritional education intervention during pregnancy on birth outcomes in sub-Saharan Africa : a protocol for a systematic review and meta-analysis

Introduction Nutritional education intervention during pregnancy is the process of teaching pregnant women about the importance of a healthy diet and how to make healthy food choices. It is an important part of public health and vital to preventing adverse birth outcomes. Therefore, synthesising available evidence on the effect of nutritional education intervention on birth outcomes is essential f

Modeling and Control of Pharmacological Systems

Personalized patient care has gained increasing attention in recent years. Precise drug dosing is critical for patient safety and good clinical outcomes, especially in intensive care units, where patients often are in critical conditions. Such treatments can include stabilizing blood pressure and heart rate or maintaining safe anesthesia levels. However, the inter-patient variability in the drug r

Use of 4 Open-Ended Text Responses to Help Identify People at Risk of Gaming Disorder : Preregistered Development and Usability Study Using Natural Language Processing

Background: Words are a natural way to describe mental states in humans, while numerical values are a convenient and effective way to carry out quantitative psychological research. With the growing interest of researchers in gaming disorder, the number of screening tools is growing. However, they all require self-quantification of mental states. The rapid development of natural language processing

Chalcogen Impurities in Silicon

If an atom of the host lattice in silicon is replaced by an atom belonging to the fifth group in the periodic table, the potential binding the extra electron to the impurity atom can, in most cases, be approximated by a hydrogen-like potential. 1 This gives rise not only to an energy level in the band gap for the impurity ground state, but, in addition, also to a series of excited states. In silic