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Climate data induced uncertainty in model-based estimations of terrestrial primary productivity

Model-based estimations of historical fluxes and pools of the terrestrial biosphere differ substantially. These differences arise not only from differences between models but also from differences in the environmental and climatic data used as input to the models. Here we investigate the role of uncertainties in historical climate data by performing simulations of terrestrial gross primary product

Identification of sequence variants influencing immunoglobulin levels

Immunoglobulins are the effector molecules of the adaptive humoral immune system. In a genome-wide association study of 19,219 individuals, we found 38 new variants and replicated 5 known variants associating with IgA, IgG or IgM levels or with composite immunoglobulin traits, accounted for by 32 loci. Variants at these loci also affect the risk of autoimmune diseases and blood malignancies and in

Prosthetic and Orthotic Rehabilitation Service in Madagascar - the Staff´s Experience at two Rehabilitation Centres

BACKGROUND Madagascar is the fourth biggest island and one of the poorest countries in the world, with more than 75 % of the 24 million inhabitants living under poverty line. The health care system in the country is under development, as well as the field of rehabilitation services and the area of prosthetic and orthotic services in specific. There is very limited published research concerning reh

Wellbeing of persons with disabilities using lower limb assistive devices devices in low-income countries

To understand what is required to improve prosthetic and orthotic provision and services for persons with disabilities in low-income countries, it is of interest to investigate their well-being in terms of quality of life, access to mobility, education, health, rehabilitation, work and employment and their experiences of attitudes in the society. Data was collected using WHOQOL questionnaires meas

Image, Imageability and the Intrepreneur : Exploring the Politics of Knowledge Work

Although previous studies have shown that image production and visibility are central aspects of knowledge work, the assumption has been that this aspect of work is focused externally to support the organizational image and or uphold relationships with clients. In contrast, this paper explores the politics of knowledge work internally by focusing on how entrepreneurial employees in innovative know

Leptin/Adiponectin Ratios Using Either Total Or High-Molecular-Weight Adiponectin as Biomarkers of Systemic Insulin Sensitivity in Normoglycemic Women

Plasma leptin/adiponectin ratio (LAR) is negatively associated with insulin sensitivity indexes. High-molecular-weight adiponectin (HMWA) was proposed as the most biologically active form of this insulin-sensitizing adipokine. There are no studies assessing the relative merits of leptin/HMWA ratio over LAR as a biomarker of systemic insulin sensitivity. A standard 2-hour oral glucose tolerance tes