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Consensus-based recommendations for diagnosis and surgical management of cranioplasty and post-traumatic hydrocephalus from a European panel

Introduction: Planning cranioplasty (CPL) in patients with suspected or proven post-traumatic hydrocephalus (PTH) poses a significant management challenge due to a lack of clear guidance. Research question: This project aims to create a European document to improve adherence and adapt to local protocols based on available resources and national health systems. Methods: After a thorough non-systema

Evaluation of Pyrophosphate‐Driven Proton Pumps in Saccharomyces cerevisiae under Stress Conditions

In Saccharomyces cerevisiae, pH homeostasis is reliant on ATP due to the use of proton-translocating ATPase (H+-ATPase) which constitutes a major drain within cellular ATP supply. Here, an exogenous proton-translocating pyrophosphatase (H+-PPase) from Arabidopsis thaliana, which uses inorganic pyrophosphate (PPi) rather than ATP, was evaluated for its effect on reducing the ATP burden. The H+-Ppas

Development of Perovskite Nanocrystal Superlattices for Studies of Collective Phenomena

Colloidal perovskite nanocrystals are building blocks for novel materials due to the property of nanocrystals to self-assemble into ordered structures (superlattices). Exemplified by a prototypical perovskite CsPbBr3, research into perovskite nanocrystal superlattices is motivated by reports of intriguing phenomena such as superfluorescence and superradiance.[1] Such cooperative luminescence arise

The chromosome resembles more a crystal than other cell organelles

Several organelles in the cell, such as mitochondria and chloroplasts, are lim-ited by one or several membranes, whereas others, like ribosomes and nucleoli have no membranes. Their shape is decided by their inner atomic coherence. The mineral crystal has no delimiting membranes built by separate atoms. Atomic self-assembly deter-mines its pattern. Remarkable is that the chromosome has no outer me

Hybridization and gene expression : Beyond differentially expressed genes

Gene expression has a key role in reproductive isolation, and studies of hybrid gene expression have identified mechanisms causing hybrid sterility. Here, we review the evidence for altered gene expression following hybridization and outline the mechanisms shown to contribute to altered gene expression in hybrids. Transgressive gene expression, transcending that of both parental species, is pervas

Birth Care Belief Practices: Traditional Mother-Child Care during Birth in Rural Punjab, Pakistan

This article analyses the birth care beliefs practiced in a Punjabi village. Birth care is an important practice that ensures a safe and uncomplicated birth for both mother and child. The study presents an in-depth exploration of the human–divine connection and its symbolic manifestation in birth care rituals in rural Muslim communities. Utilising unstructured interviews with midwives, mothers, el

HLA Class II (DR, DQ, DP) Genes Were Separately Associated With the Progression From Seroconversion to Onset of Type 1 Diabetes Among Participants in Two Diabetes Prevention Trials (DPT-1 and TN07)

OBJECTIVE: To explore associations of HLA class II genes (HLAII) with the progression of islet autoimmunity from asymptomatic to symptomatic type 1 diabetes (T1D).RESEARCH DESIGN AND METHODS: Next-generation targeted sequencing was used to genotype eight HLAII genes (DQA1, DQB1, DRB1, DRB3, DRB4, DRB5, DPA1, DPB1) in 1,216 participants from the Diabetes Prevention Trial-1 and Randomized Diabetes P

Gap Junctions May Have A Computational Function In The Cerebellum : A Hypothesis

In the cerebellum, granule cells make parallel fibre contact on (and excite) Golgi cells and Golgi cells inhibit granule cells, forming an open feedback loop. Parallel fibres excite Golgi cells synaptically, each making a single contact. Golgi cells inhibit granule cells in a structure called a glomerulus almost exclusively by GABA spillover acting through extrasynaptic GABAA receptors. Golgi cell

The Political Economy of Central Asian Law: A Law and Society Analysis

This open-access book provides fresh and much-needed insights into the interconnections between law, society and governance in Central Asia. By taking the interdisciplinary perspective of law and society, the book explores the social life of law and legal institutions in Central Asia in broader terms, encompassing not only the state legal system and institutions but also various informal (non-lega

The Public, The Police, and The Puzzle of Information

When humans are involved, things can go wrong. This is a statement as factually true and yet dramatically undefined and dangerously ambiguous as any. No matter the industry or domain, where humans interact with other humans, perfect predictability is impossible and a focus on negative outcomes can seem natural. When outcomes are anything less than ideal and when these events and outcomes are made

Towards Regenerative Supply Networks : a design framework proposal

Anthropocentrism and disciplinary research have not led to effective solutions to sustainability problems. A shift is required towards biocentric, transdisciplinarity-based solutions, to mitigate rebound effects and unintended, negative effects. In the field of Sustainable Supply Network Design, such shift implies on developing resilient solutions that maximize environmental benefits instead of mi

Method—Setups and Protocols for Operando Batteries Experiments at Variable Temperatures Applied to CaxTiS2 and Na3−xV2(PO4)3

In this paper, we present two thermalized setups for in situ operando X-ray diffraction data collection in temperature ranging from 0° to 100 °C: a modified Leriche cell and a coin cell chamber. Both setups proved proper thermalization and representative electrochemistry. While the coin cell chamber may only be used in transmission mode, the modified Leriche cell can also be used in reflection mod

Ambivalent Images of Authorship

This chapter focuses on the question of Birgitta of Sweden’s and Catherine of Siena’s status as authors with emphasis on the visual representations of the two women in the manuscripts containing their texts. Images found in the earliest extant codices portray Birgitta in the act of writing—an extremely uncommon visual rendering of a female author in the medieval period—whereas Catherine is never d

Den svenska förvaltningsmodellen och EU-rättsliga krav på oberoende myndigheter

Denna europapolitiska analys handlar om den svenska förvaltningsmodellen och hur den fungerar i förhållande till EU-rättsliga krav på oberoende myndigheter. Bakgrunden är att EU:s sekundärrätt ibland kräver att nationella förvaltningsmyndigheter som genomför EU-rätten ska vara oberoende. De tydligaste kraven handlar om tillsynsmyndigheter för dataskydd i allmänna dataskyddsförordningen (GDPR).Den

PhD Students’ Transformative Change in Teaching : A Comparative Case Study

As future academics, Doctor of Philosophy (PhD) students are be expected to employ learning-centred approach as stated in the Paris Communique (2018) by the European ministers of education. The limited research available about doctoral students’ conceptions indicates that they range from content- to learning-centred. Although a few studies explored the factors which prompt students’ transformation

Drunk Elephant: The New Toys’R’Us?

Drunk Elephant, a skincare brand known for its clean ingredients and cheerful branding, has experienced a surge in popularity driven by Gen Alpha's unexpected adoption on social media. While this newfound audience has boosted sales, concerns are mounting regarding the impact of early exposure to beauty standards and consumption habits on young children. This business case explores the challeng

A second-order perturbation method for fuzzy eigenvalue problems

Purpose - For eigenvalue problems containing uncertain inputs characterized by fuzzy basic parameters, first-order perturbation methods have been developed to extract eigen solutions, but either the result accuracy or the computational efficiency of these methods is less satisfactory. The purpose of this paper is to present an efficient method for estimation of fuzzy eigenvalues with high accuracy