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Maternal drug abuse during pregnancy is a rapidly escalating societal problem. Psychostimulants, including amphetamine, cocaine, and methamphetamine, are amongst the illicit drugs most commonly consumed by pregnant women. Neuropharmacology concepts posit that psychostimulants affect monoamine signaling in the nervous system by their affinities to neurotransmitter reuptake and vesicular transporter
Introduction: A hospital environment can be a significant burden and a health risk especially for dementia patients. Mobile x-ray equipment (ME) is used to enable imaging of these patients at home. The aim was to compare image quality (IQ) of chest, hip and pelvis images from ME to the stationary equipment (SE) used in a hospital department. Methods: We analysed examinations of the chest (n = 20),
There is a well-documented tension in many nonprofts - particularly those seeking government contracts or working in areas that compete with the private sector - between the institutional logics of business-market and nonproft-mission. This paper presents a case study of a century old Swedish nonproft. It suggests that in the presence of competing hybrid logics, organizational actors respond accor
Background: Severe inflammatory airway diseases are associated with inflammation that does not resolve, leading to structural changes and an overall environment primed for exacerbations. Objective: We sought to identify and inhibit pathways that perpetuate this heightened inflammatory state because this could lead to therapies that allow for a more quiescent lung that is less predisposed to sympto
Aim: Attention-deficit/hyperactivity disorder (ADHD) is the most common diagnosis within child- and adolescent psychiatry. Waiting lists and delayed care are major issues. The aim was to evaluate if standardized care (SC) for assessment and treatment of uncomplicated ADHD would reduce resource utilization and increase satisfaction with preserved improvement within the first year of treatment. Meth
Restraint stresses appear in structural parts which are prevented from adjusting their shape when subjected to e.g. shrinkage or thermal actions. If the restrained stresses are large, cracking might occur, which can affect the durability of the structure. In the case of restraint effects, the reinforcement required in a bridge to limit the crack widths can be difficult to determine, as the magnitu
The complement system plays an important role in varying types of disease, ranging from inflammatory and autoimmune disorders to immune deficiency states. In addition, new settings have emerged where complement analysis is of interest to monitor complement-directed therapy and aid identification of transplant complications. Therefore, it is critical that clinical laboratories offer optimized and t
Massively parallel sequencing (MPS) methods are increasingly applied in forensic casework. However, adequate validation guidelines are lacking. In this work, we describe our in-house validation of the ForenSeq DNA Signature Prep Kit (Verogen) for analysis of ancestry- and phenotype-informative SNPs. We also discuss in-house validation of MPS assays in general terms. When validating the SNP assay,
Objectives: In Sweden, pneumococcal serotype distribution in adults with community-acquired pneumonia (CAP) and potential coverage of currently licensed pneumococcal conjugate vaccines (PCVs) is unknown. Methods: During 2016–2018, patients aged ≥18 years hospitalized with radiologically confirmed (RAD+) CAP were enrolled at Skåne University Hospital in a study on the etiology of CAP in Sweden (ECA
Dynamic glucose enhanced (DGE) chemical exchange saturation transfer (CEST) MRI is an emerging imaging technique that provides a molecular-specific type of image contrast, based on magnetic labelling of exchangeable protons. The technique enables the use of biodegradable sugars as contrast agents, and such compounds are believed to have less side effects than conventional MRI contrast agents. HoweDynamic glucose enhanced (DGE) chemical exchange saturation transfer (CEST) MRI is an emerging imaging technique that provides a molecular-specific type of image contrast, based on magnetic labelling of exchangeable protons. The technique enables the use of biodegradable sugars as contrast agents, and such compounds are believed to have less side effects than conventional MRI contrast agents. Howe
Following his acclaimed earlier study on mediumship and survival, Alan Gauld providesa more complete account of about 50 years of early studies on mediumship with a select group ofmediums (e.g., Mrs. Piper, Mrs. Leonard, Mrs. Dowden). He describes in detail why many if not mostof the criticisms against extraordinarily accurate accounts by these mediums do not hold waterwhen analyzed in detail. Gau
There is limited theoretically informed research on sustainability in the space tourism market. An extended model of goal-directed behaviour (EMGB) is created and verified with individual and organizational interventions, comparing space tourism experienced and non-experienced travellers. Results revealed that individual intervention has fully significant effects on all MGB constructs, while organ
The demand for an increased number of antennas at base stations is driving research on decentralized processing schemes aimed at reducing the information volume that has to be transferred to, and processed at, a central processing unit (CPU). Some of these schemes can reduce the dimensions of the data while achieving information-lossless processing with respect to centralized architectures. Howeve
Covid-19 increased the social and economic vulnerability of island societies. Swedish islands are key tourism destinations but are also home to many island residents. Previous studies have high-lighted the impact of Covid-19 on core areas, but our knowledge of its impact on island communities is lac-king. We use phenomenology to analyse how communities in small Swedish islands perceive the impact
Impulsive noise is one of the most challenging forms of interference in an underwater acoustic environment. In this paper, we present an underwater acoustic channel deconvolution method based on a sparse representation framework. The application of the method enables a channel impulse response reconstruction that is robust to impulsive noise. By exploiting the inherent structure in the channel res
