To describe the phenotype of a novel form of autosomal dominant episodic nystagmus and to identify the potential genetic aetiology. We identified several individuals in a large Swedish family affected by episodic nystagmus. In total, 39 family members from five generations were invited to participate in the study, of which 17 were included (12 affected and 5 unaffected). The phenotype of the nysta

This paper formalizes the use of integral and differential cumulants for measurements of multiparticle event-by-event transverse momentum fluctuations, rapidity fluctuations, as well as net-charge fluctuations. This enables the introduction of multiparticle balance functions, defined based on differential correlation functions (factorial cumulants), that suppress two- and three-prong resonance dec

Poorly crystalline Al and Fe minerals have high sorption capacities for phosphate anions. However, there is still uncertainty about the molecular-level distribution of phosphorus (P) species between Al and Fe mineral phases, which can be relevant for bioavailability. The present study employed synchrotron X-ray microscopic techniques to distinguish between Al- and Fe-associated P phases in two Pod

Effects of various heating temperatures (124, 129, 134, 140 or 143 °C) and holding times (1 and 4 s) on milk quality using direct and indirect heating systems at pilot scale were investigated. Vitamin degradation was observed for both direct and indirect heating and the degradation increased with increasing temperature and holding time, however, no difference could be seen between heating systems.

Background Cranial neuropathies (CN) are a rare neuropsychiatric SLE (NPSLE) manifestation. Previous studies reported that antibodies to the kinesin family member 20B (KIF20B) (anti-KIF20B) protein were associated with idiopathic ataxia and CN. We assessed anti-KIF20B as a potential biomarker for NPSLE in an international SLE inception cohort. Methods Individuals fulfilling the revised 1997 Americ

Understanding, predicting, and controlling the phenotypic consequences of genetic and environmental change is essential to many areas of fundamental and applied biology. In evolutionary biology, the generative process of development is a major source of organismal evolvability that constrains or facilitates adaptive change by shaping the distribution of phenotypic variation that selection can act

Objective: The aim of the study was to investigate if time to start chemotherapy (TTC) after primary debulking surgery (PDS) impacted relative survival (RS) in advanced epithelial ovarian/fallopian tube/primary peritoneal cancer (EOC). Methods: Nationwide population-based study of women with EOC FIGO stages IIIC-IV, registered 2008–2018 in the Swedish Quality Register for Gynecologic Cancer, treat

Objective. To evaluate patient-reported outcomes (PROs) after initiation of tumor necrosis factor inhibitor (TNFi) treatment in European real-world patients with psoriatic arthritis (PsA). Further, to investigate PRO remission rates across treatment courses, registries, disease duration, sex, and age at disease onset. Methods. Visual analog scale or numerical rating scale scores for pain, fatigue,

We call a number representable by some given integers $a_1,\dots,a_n$, if the number can be expressed as a linear combination of $a_1,\dots,a_n$ with non-negative coefficients. This thesis explores the properties of non-representable numbers, with the main focus on the greatest such number called the Frobenius number, denoted by $g(a_1,\dots,a_n)$. We derive a simple formula when $n=2$ for the Fro

As Hamas comes into the public eye because of their attack on Israel and their civilians on 7th October 2023 so does the question on what Hamas is. Are they a resistance movement? Or are they a terrorist organization as some countries deem them? Are they something else entirely? This paper examines their original charter from 1988 through a rhetorical framework of Stephen D. O’Leary’s apocalyptic

A note with instructions for teaching the case with the same title.

The case presents Aboke-pesa, a local complementary currency in a poor rural area of Western Kenya.The reader gets an insight into the economic context of rural areas in the Global South, the work of introducing digital community currencies through farmers’ cooperatives, one of the most common designs of these currencies (mutual credit systems or LETS) as well as the particular challenges digital

Syftet med detta bidrag är alltså att kritiskt granska äldres rätt till fri rörlighetinom EU. Utgångspunkten för denna analys är artikel 3 FEU där centralavärden för EU såsom välfärd, fri rörlighet, icke-diskriminering, socialrättvisa, socialt skydd och jämställdhet mellan kvinnor och män betonas.Vårt bidrag i detta kapitel är att visa att såsom reglerna är utformade idagriskerar de att ha en kraf

Van Hove singularities (VHss) in the vicinity of the Fermi energy often play a dramatic role in the physics of strongly correlated electron materials. The divergence of the density of states generated by VHss can trigger the emergence of phases such as superconductivity, ferromagnetism, metamagnetism, and density wave orders. A detailed understanding of the electronic structure of these VHss is th

We have investigated the optical properties of heterostructured InGaN platelets aiming at red emission, intended for use as nano-scaled light-emitting diodes. The focus is on the presence of non-radiative emission in the form of dark line defects. We have performed the study using hyperspectral cathodoluminescence imaging. The platelets were grown on a template consisting of InGaN pyramids, flatte

Experimental tests of Cross Laminated Timber (CLT) under in-plane beam loading conditions are presented. The influence of the element layup, the individual lamination width, and the beam overhang at the supports on the shear force capacity was investigated. All the CLT beams had the same gross cross section, and a 4-point-bending test setup was used. The experimentally determined load-bearing capa

Due to large losses of seagrass meadows worldwide, restoration is proposed as a key strategy for increasing coastal resilience and recovery. The emergence of a seagrass meadow is expected to substantially amplify biodiversity and enhance benthic metabolism by increasing primary productivity and respiration. Nevertheless, open questions remain regarding the metabolic balance of aging seagrass meado