Effect of lipase on monoolein-based cubic phase dispersion (cubosomes) and vesicles
The effect of adding a Thermomyces (formerly Humicola) lanuginosa lipase (TLL) to a cubic dispersion of the binary monoolein (MO)-(H2O)-H-2 system and to vesicles formed by the ternary MO-sodium oleate (NaO)(H2O)-H-2 system at high water content has been studied. The change in lipid aggregate structure during the lipolytic process was observed by light microscopy, cryo-TEM, and dynamic light scatt