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Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis

Neutrophils are crucial mediators of host defense that are recruited to the central nervous system (CNS) in large numbers during acute bacterial meningitis caused by Streptococcus pneumoniae. Neutrophils release neutrophil extracellular traps (NETs) during infections to trap and kill bacteria. Intact NETs are fibrous structures composed of decondensed DNA and neutrophil-derived antimicrobial prote

Antiretroviral therapy coverage associated with increased co-residence between older and working-age adults in Africa

OBJECTIVES: To determine whether national antiretroviral therapy (ART) coverage is associated with changes in the living arrangements of older adults.DESIGN: Retrospective analysis using 103 nationally representative surveys from 28 African countries between 1991 and 2015.METHODS: The sample consisted of individuals aged at least 60 years. We investigated how three measures of living arrangements

Sex, hormonal factors and pancreatic cancer

Pancreatic cancer represents three percent of all incident cancer cases in developed countries, but stands the 7th most common cause of cancer related death. Worldwide, pancreatic cancer is more common among men, however in Sweden, the incidence ratio between sexes is levelling. Despite extensive research to map underlying risk factors, results are still largely inconclusive. Furthermore, there is

Massive MIMO: Prototyping, Proof-of-Concept and Implementation

Wireless communication is evolving rapidly with ever more connected devicesand significantly increasing data rates. Since the invention of the smartphoneand the mass introduction of mobile apps, users demand more andmore traffic to stream music, watch high-definition video or to simply browsethe internet. This tremendous growth is more pronounced by the introductionof the Internet of Things (IoT)

Indicators of candidates for gentrification: a spatial framework

PurposeThe purpose of this paper is to establish measurable factors that can be used as early indicators of which neighborhoods are most likely to undergo a process of gentrification in a reasonably near future.Design/methodology/approachUsing 1990 data on key demographic variables for 128 neighborhoods in Stockholm, Sweden a model that allows both for testing of spatial clustering and for spatial

Doctors as Patients : An Interpretative Study of Two Literary Narratives

Medical practice could be described as a drama in which doctors and patients are two actors with very different roles to play. While doctoring has traditionally been regarded as a rational and reliable activity, patienthood has been characterised by compliance with, and confidence, in the medical system. However, when doctors become ill this dichotomisation of medical practice is challenged. The a