The exact workings of amelogenin (AMG) as a key-regulator in the formation of enamel is still to be determined. It has been observed however, that AMG promotes tissue-regrowth and has promotive effect on e.g., osteoblastic cells and could therefore be of interest for medical applications. This project aimed to utilize AMG’s self-assembly properties to fabricate a protein-based biomaterial for cult

Breast reconstruction is a given choice for many women following mastectomy. There are a multitude of methods available today, and thus, comparative studies are essential to match patients with suitable methods. The aim of this study was to compare 5-year outcomes following delayed breast reconstruction with expander prosthesis (EP) and with deep inferior epigastric perforator (DIEP) flaps. Sevent

The formation of metamorphic zircon after baddeleyite is a well-known reaction that can be used to date the metamorphism of igneous silica-undersaturated rocks. By contrast, metamorphic minerals formed after igneous zirconolite have rarely been reported. In this paper, we document metamorphic titanite + zircon pseudomorphs formed from the metamorphic breakdown of igneous zirconolite in syenodiorit

The ability to learn new tasks and quickly adapt to different variations or dimensions is an important attribute in agile robotics. In our previous work, we have explored Behavior Trees and Motion Generators (BTMGs) as a robot arm policy representation to facilitate the learning and execution of assembly tasks. The current implementation of the BTMGs for a specific task may not be robust to the ch

We present a geometric approach to portfolio theory with a focus on risk-adjusted returns, in particular Jensen’s alpha. We find that while the alpha/beta approach has severe limitations, especially in higher dimensions, only minor conceptual modifications (e.g., using orthogonal Sharpe ratios rather than risk-adjusted returns) are needed to identify the efficient trading strategies. We further sh

Brain cell structure and function reflect neurodevelopment, plasticity, and aging; and changes can help flag pathological processes such as neurodegeneration and neuroinflammation. Accurate and quantitative methods to noninvasively disentangle cellular structural features are needed and are a substantial focus of brain research. Diffusion-weighted MRS (dMRS) gives access to diffusion properties of

Recombinant adeno-associated viral vectors (rAAVs) have become an industry-standard technology in the field of gene therapy, but there are still challenges to be addressed in their biomanufacturing. One of the biggest challenges is the removal of capsid species other than that which contains the gene of interest. In this work, we develop a mechanistic model for the removal of empty capsids—those t

Several sources of DNA damage compromise the integrity and stability of the genome of every organism. Specifically, DNA double-strand breaks (DSBs) can have lethal consequences for the cell. To repair this type of DNA damage, the cells employ homology-directed repair pathways or non-homologous end joining. Homology-directed repair requires the activity of the RAD52 epistasis group of genes. Rad52

The food industry is vital manufacturing sector globally, with an ever-increasing reliance on digitalisation and technology-driven processes. However, this advancement introduces inherent cyberattack risks, encompassing data breaches and system disruptions, which can severely impact production and disrupt the entire food chain. Consequently, cyber threats can evoke fear and mistrust among consumer

This study investigates the effects of temperature and relative humidity (RH) on the formation of secondary organic aerosol (SOA) from Δ3-carene, a prevalent monoterpene in boreal forests. Dark ozonolysis experiments of 10 ppb Δ3-carene were conducted in the Aarhus University Research on Aerosol (AURA) atmospheric simulation chamber at temperatures of 0, 10, and 20 °C. Under dry conditions (RH < 2

Volume loading of the right ventricle (RV) in patients with atrial septal defect (ASD) and patients with repaired Tetralogy of Fallot (rToF) affects the pumping mechanics of the left ventricle (LV). Intervention of the lesion will relieve the RV volume load however quantifiable impact on exercise capacity, arrhytmias or death are limited. A possible explanation could be remaining effects on the fu

How was the scope of nuclear weapons policy change immediately after the Cold War determined? Nuclear learning and worst-case thinking are common but not satisfactory answers. On the basis of primary sources in multiple languages, we posit that a particular temporalization of nuclear events in the beginning of the 1990s took place: nonproliferation timescaping. The Iraqi case of opaque proliferati

Social workers often fail to engage fathers in child protection investigations (CPIs), especially when they involve domestic abuse (DA) by fathers. The aim of this study is to examine the strategies used by social workers to achieve cooperation with fathers in CPIs that involve the father being suspected of DA against the child's mother. With the use of qualitative methods, we conducted 31 semi-st

A competition process on Zd is considered, where two species compete to color the sites. The entities are driven by branching random walks. Specifically red (blue) particles reproduce in discrete time and place offspring according to a given reproduction law, which may be different for the two types. When a red (blue) particle is placed at a site that has not been occupied by any particle before,

Vehicular networks connect vehicles for improved road safety and efficiency with the assistance of wireless information exchange. Vehicular networks are based on the frequent broadcast of awareness messages referred to as CAM (Cooperative Awareness Messages) or BSM (Basic Safety Message) in the ETSI and SAE standards, respectively. Vehicular network technology mostly used nowadays is based on cell

This study focuses on the characterization of NaCl-induced enhancement of H+ exchange catalysis and preparation of the renewable C6 platform chemical, 5-(hydroxymethyl)furfural (5-HMF), through dehydration of fructose and glucose, C6-sugars, utilizing a heterogeneous catalyst. The effect of a catalytic amount of NaCl was explored to enhance the H+ exchange of cation exchangers, characterized on th