This book illustrates the program of Logical-Informational Dynamics. Rational agents exploit the information available in the world in delicate ways, adopt a wide range of epistemic attitudes, and in that process, constantly change the world itself. Logical-Informational Dynamics is about logical systems putting such activities at center stage, focusing on the events by which we acquire informatio

Sustainable development is currently said to be an overriding development goal, also for development assistance. It requires new approaches that challenge not only economic rationality but also bureaucracies in ways that encourage political pluralism and the participation by civil society. As the gap between rich and poor increases and as the pressures on already strained systems constantly increa

This thesis focuses on the possibilities to reduce fouling by 1.Modifying the stainless steel surface. For this purpose, surfaces modified with state-of-the-art material science techniques, such as SiF3+ and MoS22+ ion implantation, Diamond-like Carbon (DLC) sputtering, DLC, DLC-Si-O and SiOx Plasma Enhanced Chemical Vapour Deposition (PECVD), autocatalytic Ni-P-PTFE and silica coating, have been

Popular Abstract in English The present work deals with fracture in structures which are exposed to relatively few cycles of static loading during their life-time (maximum some ten thousand). Structures exposed to nearly monotonic loading are rare, except for such loaded mainly by their own weight. In spite of this fact, fracture mechanic methods developed for monotone loading are commonly used onThe experimental results presented confirm the anticipation that it is extremely important not to confuse the concept of 'static loading' with the one of 'monotonic loading'. In principle three different crack configurations were investigated in: edge-cracks, internal flaws and surface cracks. The results showed that the same calculation method could be used for all the investigated crack types. T

Popular Abstract in Swedish Byggbranschen står inför stora utmaningar i att möta behovet av nya bostäder samtidigt som renoveringsbehovet av flerbostadshus är stort. Man beskylls ofta för bristande kvalitet och höga kostnader. Industriellt byggande har framförts som en lösning till problemen. I ett projekt på Lunds Universitet har två tillämpningar för industriellt byggande studerats: trähusbygganIndustrialized construction has over the years taken different expressions and gone through different phases depending on where inspiration has come from. In this project, industrialized construction has been studied in two applications: timber house manufacturing and renovation of multi-family houses. In Sweden industrialized production of timber houses is relatively strong in the housing sector

Quantum chemical and statistical mechanical methods are employed to study flexible molecular systems. Using quantum chemical methods it is demonstrated that the preference of the gauche conformation for 1,2-difluoroethane, predicted at the Hartree-Fock level, is due to a larger overlap between the singly occupied orbitals of the CFH2 radicals in the gauche conformation. The intermolecular water po

This chapter attends the history of the nature/nurture debate and asserts the constancy of biological explanations of human nature within psychiatry up to this day. It elucidates the connection between social darwinism and contemporary individualism, claiming the degeneration theory of the 19th century to be an intermediate link. Finally, it scrutinizes not only the origin of but also the conseque

Popular Abstract in Swedish Denna avhandling beskriver utvecklingen av en teknik baserad på mikrodispensering, för att skapa proteinmönster som kan användas för styrning av axoner. Samma teknik vidareutvecklades för att kunna positionera dissocierade celler, bl.a. nervceller, på cellodlingsytor. Slutligen undersöktes vilken roll galektin-3 och 8 har under nervregeneration. Avhandlingen består av fThe present thesis describes development of a microdispenser-based technique to create of protein patterns for neurite guidance. The same technique was also developed to allow direct positioning of dissociated cells, including neurons, on cell culture substrates. Finally the role of galectin-3 and 8 during nerve regeneration was investigated. The thesis consists of four papers (I-IV). Microdispen

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Popular Abstract in Swedish Defekt mismatch-reparation och familjär cancerrisk Cancer är på cellnivå en genetisk sjukdom. Förändringar i cellens arvsmassa (DNA) drabbar tre huvudtyper av gener; onkgener, tumörsuppressorgener och DNA-reparationsgener. Onkgener är en grupp gener som befrämjar cellens tillväxt. Vid cancerutveckling aktiveras onkgener via mutation eller genom ökat uttryck, vilket ledInactivation of the DNA mismatch repair (MMR) system is a tumorigenic mechanism involved in 15-20% of tumor types such as colorectal and endometrial cancer and is specifically associated with the Hereditary Nonpolyposis Colorectal Cancer (HNPCC) syndrome. These MMR defective tumors are characterized by microsatellite instability (MSI), a phenomenon that reflects alterations in length of repeated s

Popular Abstract in Swedish När en kärlskada uppstår måste skadan repareras innan alltför mycket blod hinner lämna blodbanan. Kärlet självt kan dra ihop sig till viss del för att minska blodflödet. Vid kärlskadan exponeras strukturer som normalt inte skall ha kontakt med blodet, en sådan struktur är t.ex. ämnet kollagen. Till kollagenet binds blodplättar (trombocyter) som tillfälligt täpper till sThe investigations presented in this thesis have evaluated different strategies to prevent thrombosis in an experimental model of deep arterial injury in rats. Unfractionated heparin (UFH) is often used to prevent thrombosis in microvascular surgery and in other vascular interventions, but a major drawback of UFH is increased bleeding. In the first paper the low-molecular-weight heparin (LMWH) da

Popular Abstract in Swedish Lokal läkemedelsstatistik – ett verktyg för att identifiera problemområden och att bedöma effekter av information och utbildning om läkemedel. Det finns behov att studera läkemedelsförskrivning och läkemedelsanvändning och dessas samband med och effekter på hälsa, sjuklighet och överdödlighet. Det är också önskvärt att kunna använda individdata. I Sverige är det i allmAims: 1) To assess if drug sales data indicate differences in morbidity, mortality, socio-economic conditions and deviating prescribing habits among physicians; 2) to identify areas for educational interventions and to analyse changes in prescribing after educational activities. In addition, an effort was made to estimate differences between pharmacy sales and purchases by the population, and the