The ubiquitin (Ub) kinase-ligase pair PINK1-PRKN mediates the degradation of damaged mitochondria by macroautophagy/autophagy (mitophagy). PINK1 surveils mitochondria and upon stress accumulates on the mitochondrial surface where it phosphorylates serine 65 of Ub to activate PRKN and to drive mitochondrial turnover. While loss of either PINK1 or PRKN is genetically linked to Parkinson disease (PD)

The European Food Safety Authority (EFSA) är en EU myndighet med uppdrag att göra riskbedömningar för att stödja arbete med att upprätthålla livsmedelssäkerhet i EU. I denna studie undersöks hur EFSA kommunicerar osäkerhet i slutsatser från några av deras vetenskapliga bedömningar och om de följer den rekommenderade guiden som antogs av EFSA 2019 för kommunikation av osäkerhet. I studien har 15 stThe European Food Safety Authority (EFSA) is an EU agency, providing scientific advice and standards surrounding risk assessment in order to maintain food safety in Europe. The aim of this study was to investigate how EFSA communicates uncertainty in conditions of their assessment and if the recommended guidelines by EFSA 2019 is fulfilled. 15 Randomly picked scientific articles produced during th

'Can it ever be okay to kidnap a wife?’ This thesis combined fieldwork observations with narrative interviews from twenty-two kidnapped women from an ethnographic four- month research stay in Kyrgyzstan. From a starting point, the thesis took a normative framework, understanding that everyone has the right to equal rights. The framework relied on the global monitor mechanisms, CEDAW and CAT, w

Det finns flera sätt att begränsa konkurrensen, men det finns bestämmelser i nationell och EU-rätt som spelar in när man gör det. Syftet med denna uppsats är att analysera den rättsliga ramen i svensk nationell rätt kring konkurrens mot en arbetsgivare och undersöka under vilka förutsättningar en anställd får konkurrera mot en arbetsgivare. Uppsatsen kommer också att ta en titt på hur konkurrensklThere are several ways of restricting competition, but there are regulations in national and EU- law which come into play when doing so. The purpose of this essay is to analyse the legal framework in Swedish national law concerning competition against an employer and examine the conditions under which an employee is allowed to compete against an employer. The essay will also take a look at how com

“Together for belonging” : A case study in a not-for-profit group for immigrant mothers in Rosengård This essay examines how immigrant women in Malmö (Rosengård), use a not-for-profit group to find ways to navigate their everyday lives. The aim of the study is to get a deeper understanding of the functioning of the group. As an ethnographic case study, I participated as an observer during group me

I den tekniska och globaliserade värld vi lever i idag är arbetsmarknaden väldigt påverkad av olika trender runt om i världen. Tack vare detta så är arbetsmarknadens behov av flexibilitet större än någonsin. Detta gör att bemanningsbranschen har haft en enorm tillväxt de senaste åren. Med denna branschs frammarsch så kommer också utmaningar i arbetsrätten, speciellt när det kommer till trepartsförIn the technological and globalized world we live in today, the labor market is very affected by various trends around the world. Thanks to this, the labor market's need for flexibility is greater than ever. This means that the staffing industry has experienced tremendous growth in recent years. With the rise of this industry also comes challenges in labor law, especially when it comes to the

An iterative algorithm is adopted to construct approximate representations of matrices describing the scattering properties of arbitrary objects. The method is based on the implicit evaluation of scattering responses from iteratively generated excitations. The method does not require explicit knowledge of any system matrices (e.g., stiffness or impedance matrices) and is well-suited for use with m

Sverige är ett av Europiska Unionens mest digitaliserade länder och det finns mycket att vinna på en fortsatt anpassning till de nya förutsättningar som digitaliseringen skapar. Tjugo år efter antagandet av det befintliga rättsliga ramverket som idag är tillämpligt på området, har EU-kommissionen, som ett led av nya och innovativa affärsmodeller presenterat ett förslag till förordning som nu har aSweden is one of the most digitalized countries in the European Union, and there is much to gain from a continuous adaptation of the advantages which digitalization creates. Twenty years after adopting the current legal framework within the area, the European Commission, led by new and innovative business models, has presented a proposal for a regulation which is now adopted (The Digital Services

Har du någonsin öppnat en flaska juice på morgonen för att sedan upptäcka att den luktar bacon? I så fall är det möjligt att en typ av bakterie som kallas Alicyclobacillus (förkortad ACB) har börjat växa i juicen. Inom juice-industrin är ACB - tillsammans med jäst, mögel och andra bakterier som kan växa i sura miljöer - en av de främsta bovarna som gör att produkter måste slängas eller återkallaThe main concerns of food spoilage in fruit juices are the off-flavours and off-odours caused by microorganisms. In order to ensure high quality products, these microorganisms must therefore be eliminated or below a certain limit. Trials using pear concentrate, a ready-to-drink pear drink and a carbonated pear drink, were performed in order to compare two detection methods for three different grou

Transition metal dichalcogenide (TMDCs) monolayers make an excellent component in optoelectronic devices such as photodetectors and phototransistors. Selenide-based TMDCs, specifically molybdenum diselenide (MoSe2) monolayers with low defect densities, show much faster photoresponses compared to their sulfide counterpart. However, the typically low absorption of the atomically thin MoSe2 monolayer

This paper explores educational desires, parenting and shifting notions of childhood in contemporary Singapore. Singapore’s education system is globally renowned for its high academic standards and for producing students who excel in international assessment tests and rankings. At the same time, there has been a shift of attention in education policy towards social-emotional competencies and well-This paper explores educational desires, parenting and shifting notions of childhood in contemporary Singapore. Singapore’s education system is globally renowned for its high academic standards and for producing students who excel in international assessment tests and rankings. At the same time, there has been a shift of attention in education policy towards social-emotional competencies and well-

En hel del har skrivits om reklamationsplikten vid avtalsbrott. Trots det är rättsläget fortfarande oklart. Reklamationsplikten vid avtalsbrott är dock enbart en del av den inomkontraktuella reklamationsplikten. Högsta domstolen har under senare tid avgjort ett antal mål där en passivitetsprincip skapat en reklamationsplikt trots att det inte förelegat ett avtalsbrott. Högsta domstolen har i KravmA lot has been published about the obligation to notify the breaching party of a breach of contract. Despite that, the legal position is still unclear. The obligation to notify a breaching party of a breach of contract is just one element of the requirement to notify a party in a contractual relationship. The Supreme Court has delivered judgment in several cases in which a passivity principle crea

Idiopathic pulmonary fibrosis (IPF) is a fatal disease that exhibits patterns of usual interstitial pneumonia with honeycombing. IPF is characterized by damaged distal lung epithelium with excessive tissue scarring and extracellular matrix remodeling. The etiology of IPF is unknown and current therapies cannot end or reverse disease progression. Aberrant reactivation of developmental pathways is e

Syftet med studien var att undersöka det utvecklande ledarskapets positiva utfall i form av engagemang och upplevd effektivitet på ett medicintekniskt bolag. Vidare ämnade studien att utforska eventuella samband mellan det utvecklande ledarskapets dimensioner (föredömligt autentiskt handlande, personlig omtanke samt inspiration och motivation) och engagemang samt upplevd effektivitet. Det utvecklaThe purpose of this study was to examine the developmental leadership and its positive outcomes on a MedTech company, more specifically engagement and perceived effectiveness. Moreover, the study aimed to explore the developmental leadership dimension’s (exemplary model, individualized consideration, and inspiration and motivation) potential relationships with engagement and perceived effectivenes

Genom den popularisering som skett av feminismen har ett skifte skett i den marknadsföring som riktar sig till kvinnor, främst gällande framställningen av kvinnor i reklam. Dessutom vill många företag idag framställa sig som feminister, antingen för att de faktiskt är det, eller för att de vill utnyttja dess positiva påföljder. Det handlar alltså om två olika marknadsföringsstrategier; femvertisinThrough the popularization of feminism, a shift has taken place in the marketing aimed at women, mainly regarding the portrayal of women in advertising. In addition, many companies today want to present themselves as feminists, either because they are, or because they want to take advantage of its positive consequences. It is thus about two different marketing strategies: femvertising or femwashin

The aim of this study was to investigate how social workers in social service at child welfare experience and describe their work situation regarding workload and how they handle it when the workload is perceived as high. Individual qualitative semi-structured interviews were conducted with eight social workers who work with child welfare services. The empirical material that was obtained from the

Den här studien syftar till att undersöka och analysera hur genomförandet av övervakningsåtgärderna drogtestning, kameraövervakning och geopositioner kan resultera i en konflikt mellan arbetsrätten och GDPR. För att uppnå syftet kommer frågeställningar att besvara vilka rättsliga befogenheter arbetsgivaren har att genomföra kontrollåtgärder, hur GDPR begränsar genomförandet av kontrollåtgärder samThe purpose of the study is to analyze how employment law interact with GDPR when implementing the following monitoring actions of; drug test, camera surveillance and geopositioning at the workplace. This was investigated with three research questions looking at what right the employer has to implement monitoring actions, how GDPR limits the implementation of monitoring actions, and what contradic